Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer’s disease: In vitro and in vivo studies AH Abuznait, H Qosa, BA Busnena, KA El Sayed, A Kaddoumi ACS chemical neuroscience 4 (6), 973-982, 2013 | 329 | 2013 |
Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease H Qosa, AH Abuznait, RA Hill, A Kaddoumi Journal of Alzheimer's Disease 31 (1), 151-165, 2012 | 205 | 2012 |
Paclitaxel loaded PEG5000–DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and toxicological evaluation KK Gill, S Nazzal, A Kaddoumi European Journal of Pharmaceutics and Biopharmaceutics 79 (2), 276-284, 2011 | 203 | 2011 |
Role of ABC transporters in the pathogenesis of Alzheimer’s disease AH Abuznait, A Kaddoumi ACS chemical neuroscience 3 (11), 820-831, 2012 | 169 | 2012 |
Differences in amyloid-β clearance across mouse and human blood–brain barrier models: kinetic analysis and mechanistic modeling H Qosa, BS Abuasal, IA Romero, B Weksler, PO Couraud, JN Keller, ... Neuropharmacology 79, 668-678, 2014 | 164 | 2014 |
Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model H Qosa, YS Batarseh, MM Mohyeldin, KA El Sayed, JN Keller, ... ACS chemical neuroscience 6 (11), 1849-1859, 2015 | 160 | 2015 |
Profiling gene expression in human placentae of different gestational ages: an OPRU Network and UW SCOR Study AM Mikheev, T Nabekura, A Kaddoumi, TK Bammler, R Govindarajan, ... Reproductive sciences 15 (9), 866-877, 2008 | 147 | 2008 |
Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models AK Tiwari, K Sodani, C Dai, AH Abuznait, S Singh, ZJ Xiao, A Patel, ... Cancer letters 328 (2), 307-317, 2013 | 134 | 2013 |
Mixed micelles of PEG2000-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small … KK Gill, A Kaddoumi, S Nazzal European journal of pharmaceutical sciences 46 (1-2), 64-71, 2012 | 130 | 2012 |
Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway A Wani, SB Al Rihani, A Sharma, B Weadick, R Govindarajan, SU Khan, ... Autophagy 17 (11), 3813-3832, 2021 | 119 | 2021 |
Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice H Qosa, LA Mohamed, YS Batarseh, S Alqahtani, B Ibrahim, H LeVine III, ... The Journal of Nutritional Biochemistry 26 (12), 1479-1490, 2015 | 112 | 2015 |
PEG–lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication KK Gill, A Kaddoumi, S Nazzal Journal of drug targeting 23 (3), 222-231, 2015 | 112 | 2015 |
Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway A Wani, M Gupta, M Ahmad, AM Shah, AU Ahsan, PH Qazi, F Malik, ... Autophagy 15 (10), 1810-1828, 2019 | 104 | 2019 |
Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice YS Batarseh, SS Bharate, V Kumar, A Kumar, RA Vishwakarma, ... ACS chemical neuroscience 8 (8), 1756-1766, 2017 | 100 | 2017 |
Glial cell-mediated neuroinflammation in Alzheimer’s disease NF Al-Ghraiybah, J Wang, AE Alkhalifa, AB Roberts, R Raj, E Yang, ... International journal of molecular sciences 23 (18), 10572, 2022 | 99 | 2022 |
Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease AH Abuznait, C Cain, D Ingram, D Burk, A Kaddoumi Journal of Pharmacy and Pharmacology 63 (8), 1111-1118, 2011 | 98 | 2011 |
Amyloid-β and astrocytes interplay in amyloid-β related disorders YS Batarseh, QV Duong, YM Mousa, SB Al Rihani, K Elfakhri, ... International journal of molecular sciences 17 (3), 338, 2016 | 95 | 2016 |
Experimental models for predicting drug absorption and metabolism S Alqahtani, LA Mohamed, A Kaddoumi Expert Opinion on Drug Metabolism & Toxicology 9 (10), 1241-1254, 2013 | 95 | 2013 |
Enhancement of intestinal permeability utilizing solid lipid nanoparticles increases γ-tocotrienol oral bioavailability BS Abuasal, C Lucas, B Peyton, A Alayoubi, S Nazzal, PW Sylvester, ... Lipids 47, 461-469, 2012 | 93 | 2012 |
Cellular uptake, antioxidant and antiproliferative activity of entrapped α-tocopherol and γ-tocotrienol in poly (lactic-co-glycolic) acid (PLGA) and chitosan covered PLGA … S Alqahtani, L Simon, CE Astete, A Alayoubi, PW Sylvester, S Nazzal, ... Journal of colloid and interface science 445, 243-251, 2015 | 92 | 2015 |