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Justin R Cross
Justin R Cross
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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
N Arpaia, C Campbell, X Fan, S Dikiy, J Van Der Veeken, P Deroos, H Liu, ...
Nature 504 (7480), 451-455, 2013
46242013
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
PS Ward, J Patel, DR Wise, O Abdel-Wahab, BD Bennett, HA Coller, ...
Cancer cell 17 (3), 225-234, 2010
24082010
ATP-citrate lyase links cellular metabolism to histone acetylation
KE Wellen, G Hatzivassiliou, UM Sachdeva, TV Bui, JR Cross, ...
Science 324 (5930), 1076-1080, 2009
23212009
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
CG Buffie, V Bucci, RR Stein, PT McKenney, L Ling, A Gobourne, D No, ...
Nature 517 (7533), 205-208, 2015
19772015
Toll-like receptor–induced changes in glycolytic metabolism regulate dendritic cell activation
CM Krawczyk, T Holowka, J Sun, J Blagih, E Amiel, RJ DeBerardinis, ...
Blood, The Journal of the American Society of Hematology 115 (23), 4742-4749, 2010
13432010
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
DR Wise, PS Ward, JES Shay, JR Cross, JJ Gruber, UM Sachdeva, ...
Proceedings of the National Academy of Sciences 108 (49), 19611-19616, 2011
11352011
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
BW Carey, LWS Finley, JR Cross, CD Allis, CB Thompson
Nature 518 (7539), 413-416, 2015
9772015
Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
Q Chen, A Boire, X Jin, M Valiente, EE Er, A Lopez-Soto, L S. Jacob, ...
Nature 533 (7604), 493-498, 2016
9222016
Connecting copper and cancer: from transition metal signalling to metalloplasia
EJ Ge, AI Bush, A Casini, PA Cobine, JR Cross, GM DeNicola, QP Dou, ...
Nature Reviews Cancer 22 (2), 102-113, 2022
9062022
Clinical and biological correlates of neurotoxicity associated with CAR T-cell therapy in patients with B-cell acute lymphoblastic leukemia
BD Santomasso, JH Park, D Salloum, I Riviere, J Flynn, E Mead, E Halton, ...
Cancer discovery 8 (8), 958-971, 2018
8282018
Intestinal Blautia is associated with reduced death from graft-versus-host disease
RR Jenq, Y Taur, SM Devlin, DM Ponce, JD Goldberg, KF Ahr, ...
Biology of Blood and Marrow Transplantation 21 (8), 1373-1383, 2015
7842015
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
JJ Kamphorst, JR Cross, J Fan, E De Stanchina, R Mathew, EP White, ...
Proceedings of the National Academy of Sciences 110 (22), 8882-8887, 2013
7562013
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells
C Campbell, PT McKenney, D Konstantinovsky, OI Isaeva, M Schizas, ...
Nature 581 (7809), 475-479, 2020
6502020
Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation
BR Sabari, Z Tang, H Huang, V Yong-Gonzalez, H Molina, HE Kong, ...
Molecular cell 58 (2), 203-215, 2015
5702015
Hypoxia induces production of L-2-hydroxyglutarate
AM Intlekofer, RG Dematteo, S Venneti, LWS Finley, C Lu, AR Judkins, ...
Cell metabolism 22 (2), 304-311, 2015
5032015
Commensal bacteria make GPCR ligands that mimic human signalling molecules
LJ Cohen, D Esterhazy, SH Kim, C Lemetre, RR Aguilar, EA Gordon, ...
Nature 549 (7670), 48-53, 2017
4642017
Serine catabolism regulates mitochondrial redox control during hypoxia
J Ye, J Fan, S Venneti, YW Wan, BR Pawel, J Zhang, LWS Finley, C Lu, ...
Cancer discovery 4 (12), 1406-1417, 2014
4612014
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion
J Zhang, J Fan, S Venneti, JR Cross, T Takagi, B Bhinder, H Djaballah, ...
Molecular cell 56 (2), 205-218, 2014
4352014
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
EE Govek, SE Newey, CJ Akerman, JR Cross, L Van der Veken, ...
Nature neuroscience 7 (4), 364-372, 2004
3742004
Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen
SA Vardhana, MA Hwee, M Berisa, DK Wells, KE Yost, B King, M Smith, ...
Nature immunology 21 (9), 1022-1033, 2020
3602020
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