A genome-wide association study identifies novel risk loci for type 2 diabetes R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D Serre, P Boutin, ... Nature 445 (7130), 881-885, 2007 | 3804 | 2007 |
Islet β cell failure in type 2 diabetes M Prentki, CJ Nolan The Journal of clinical investigation 116 (7), 1802-1812, 2006 | 2359 | 2006 |
Type 2 diabetes across generations: from pathophysiology to prevention and management CJ Nolan, P Damm, M Prentki The Lancet 378 (9786), 169-181, 2011 | 1345 | 2011 |
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and-independent glucose-stimulated insulin secretion. HE Hohmeier, H Mulder, G Chen, R Henkel-Rieger, M Prentki, ... Diabetes 49 (3), 424-430, 2000 | 1070 | 2000 |
AMPK, insulin resistance, and the metabolic syndrome NB Ruderman, D Carling, M Prentki, JM Cacicedo The Journal of clinical investigation 123 (7), 2764-2772, 2013 | 988 | 2013 |
Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion M Prentki, FM Matschinsky Physiological reviews 67 (4), 1185-1248, 1987 | 970 | 1987 |
Saturated fatty acids synergize with elevated glucose to cause pancreatic β-cell death W El-Assaad, J Buteau, ML Peyot, C Nolan, R Roduit, S Hardy, E Joly, ... Endocrinology 144 (9), 4154-4163, 2003 | 780 | 2003 |
Are the β-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? M Prentki, BE Corkey Diabetes 45 (3), 273-283, 1996 | 659 | 1996 |
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in β-cell adaptation and failure in the etiology of diabetes M Prentki, E Joly, W El-Assaad, R Roduit Diabetes 51 (suppl_3), S405-S413, 2002 | 637 | 2002 |
Metabolic signaling in fuel-induced insulin secretion M Prentki, FM Matschinsky, SRM Madiraju Cell metabolism 18 (2), 162-185, 2013 | 620 | 2013 |
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome N Ruderman, M Prentki Nature reviews Drug discovery 3 (4), 340-351, 2004 | 581 | 2004 |
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia J Rung, S Cauchi, A Albrechtsen, L Shen, G Rocheleau, ... Nature genetics 41 (10), 1110-1115, 2009 | 560 | 2009 |
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA … J Buteau, R Roduit, S Susini, M Prentki Diabetologia 42, 856-864, 1999 | 560 | 1999 |
Glucagon-like peptide 1 induces pancreatic β-cell proliferation via transactivation of the epidermal growth factor receptor J Buteau, S Foisy, E Joly, M Prentki Diabetes 52 (1), 124-132, 2003 | 548 | 2003 |
Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. M Prentki, S Vischer, MC Glennon, R Regazzi, JT Deeney, BE Corkey Journal of Biological Chemistry 267 (9), 5802-5810, 1992 | 545 | 1992 |
Fatty acid signaling in the β-cell and insulin secretion CJ Nolan, MSR Madiraju, V Delghingaro-Augusto, ML Peyot, M Prentki Diabetes 55 (Supplement_2), S16-S23, 2006 | 534 | 2006 |
Metabolic fate of glucose in purified islet cells: glucose-regulated anaplerosis in β cells F Schuit, A De Vos, S Farfari, K Moens, D Pipeleers, T Brun, M Prentki Journal of Biological Chemistry 272 (30), 18572-18579, 1997 | 529 | 1997 |
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in … H Park, VK Kaushik, S Constant, M Prentki, E Przybytkowski, ... Journal of Biological Chemistry 277 (36), 32571-32577, 2002 | 501 | 2002 |
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity J Buteau, W El-Assaad, CJ Rhodes, L Rosenberg, E Joly, M Prentki Diabetologia 47, 806-815, 2004 | 488 | 2004 |
Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate M Prentki, TJ Biden, D Janjic, RF Irvine, MJ Berridge, CB Wollheim Nature 309 (5968), 562-564, 1984 | 458 | 1984 |