| The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition DR Littler, SJ Harrop, WD Fairlie, LJ Brown, GJ Pankhurst, S Pankhurst, ... Journal of Biological Chemistry 279 (10), 9298-9305, 2004 | 271 | 2004 |
| The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins? DR Littler, SJ Harrop, SC Goodchild, JM Phang, AV Mynott, L Jiang, ... FEBS letters 584 (10), 2093-2101, 2010 | 226 | 2010 |
| Crystal structure of the SARS-CoV-2 non-structural protein 9, Nsp9 DR Littler, BS Gully, RN Colson, J Rossjohn Iscience 23 (7), 2020 | 203 | 2020 |
| Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence DR Littler, M Alvarez-Fernandez, A Stein, RG Hibbert, T Heidebrecht, ... Nucleic acids research 38 (13), 4527-4538, 2010 | 172 | 2010 |
| A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B W Nijenhuis, E Von Castelmur, D Littler, V De Marco, E Tromer, M Vleugel, ... Journal of Cell Biology 201 (2), 217-231, 2013 | 159 | 2013 |
| Crystal structure of the soluble form of the redox‐regulated chloride ion channel protein CLIC4 DR Littler, NN Assaad, SJ Harrop, LJ Brown, GJ Pankhurst, P Luciani, ... The FEBS journal 272 (19), 4996-5007, 2005 | 148 | 2005 |
| In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein NK Williams, P Prosselkov, E Liepinsh, I Line, A Sharipo, DR Littler, ... Journal of Biological Chemistry 277 (10), 7790-7798, 2002 | 137 | 2002 |
| Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases MPA Luna-Vargas, E Christodoulou, A Alfieri, WJ van Dijk, M Stadnik, ... Journal of structural biology 175 (2), 113-119, 2011 | 111 | 2011 |
| Oxidation promotes insertion of the CLIC1 chloride intracellular channel into the membrane SC Goodchild, MW Howell, NM Cordina, DR Littler, SN Breit, PMG Curmi, ... European biophysics journal 39, 129-138, 2009 | 90 | 2009 |
| Molecular basis of cytokine receptor activation AF Lopez, TR Hercus, P Ekert, DR Littler, M Guthridge, D Thomas, ... IUBMB life 62 (7), 509-518, 2010 | 87 | 2010 |
| Structure of the Janus protein human CLIC2 BA Cromer, MA Gorman, G Hansen, JJ Adams, M Coggan, DR Littler, ... Journal of molecular biology 374 (3), 719-731, 2007 | 82 | 2007 |
| Comparison of vertebrate and invertebrate CLIC proteins: The crystal structures of Caenorhabditis elegans EXC‐4 and Drosophila melanogaster DmCLIC DR Littler, SJ Harrop, LJ Brown, GJ Pankhurst, AV Mynott, P Luciani, ... Proteins: Structure, Function, and Bioinformatics 71 (1), 364-378, 2008 | 79 | 2008 |
| Polo-box domains confer target specificity to the Polo-like kinase family BCM van de Weerdt, DR Littler, R Klompmaker, A Huseinovic, A Fish, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (6), 1015-1022, 2008 | 74 | 2008 |
| Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA B Ponsioen, L van Zeijl, M Langeslag, M Berryman, D Littler, K Jalink, ... Molecular biology of the cell 20 (22), 4664-4672, 2009 | 65 | 2009 |
| Metamorphic response of the CLIC1 chloride intracellular ion channel protein upon membrane interaction SC Goodchild, MW Howell, DR Littler, RA Mandyam, KL Sale, M Mazzanti, ... Biochemistry 49 (25), 5278-5289, 2010 | 52 | 2010 |
| A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation DR Littler, JR Walker, T Davis, LE Wybenga-Groot, PJ Finerty, E Newman, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 46 | 2010 |
| A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein DR Littler, M Liu, JL McAuley, SA Lowery, PT Illing, BS Gully, AW Purcell, ... Journal of Biological Chemistry 297 (6), 2021 | 44 | 2021 |
| Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor MT Rice, A von Borstel, P Chevour, W Awad, LJ Howson, DR Littler, ... Proceedings of the National Academy of Sciences 118 (49), e2110288118, 2021 | 43 | 2021 |
| The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1 T Heidebrecht, E Christodoulou, MJ Chalmers, S Jan, B Ter Riet, ... Nucleic acids research 39 (13), 5715-5728, 2011 | 42 | 2011 |
| Structure of human CLIC3 at 2 Å resolution DR Littler, LJ Brown, SN Breit, A Perrakis, PMG Curmi Proteins: Structure, Function, and Bioinformatics 78 (6), 1594-1600, 2010 | 42 | 2010 |
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