| Serine ADP-ribosylation depends on HPF1 JJ Bonfiglio, P Fontana, Q Zhang, T Colby, I Gibbs-Seymour, I Atanassov, ... Molecular cell 65 (5), 932-940. e6, 2017 | 340 | 2017 |
| HPF1/C4orf27 is a PARP-1-interacting protein that regulates PARP-1 ADP-ribosylation activity I Gibbs-Seymour, P Fontana, JGM Rack, I Ahel Molecular cell 62 (3), 432-442, 2016 | 317 | 2016 |
| Serine ADP-ribosylation reversal by the hydrolase ARH3 P Fontana, JJ Bonfiglio, L Palazzo, E Bartlett, I Matic, I Ahel Elife 6, e28533, 2017 | 245 | 2017 |
| HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation MJ Suskiewicz, F Zobel, TEH Ogden, P Fontana, A Ariza, JC Yang, K Zhu, ... Nature 579 (7800), 598-602, 2020 | 237 | 2020 |
| DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation LR Hollingsworth, H Sharif, AR Griswold, P Fontana, J Mintseris, ... Nature 592 (7856), 778-783, 2021 | 165 | 2021 |
| Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis R Miao, C Jiang, WY Chang, H Zhang, J An, F Ho, P Chen, H Zhang, ... Immunity 56 (11), 2523-2541. e8, 2023 | 164 | 2023 |
| Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold P Fontana, Y Dong, X Pi, AB Tong, CW Hecksel, L Wang, TM Fu, ... Science 376 (6598), eabm9326, 2022 | 145 | 2022 |
| Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasion SM Vora, P Fontana, T Mao, V Leger, Y Zhang, TM Fu, J Lieberman, ... Proceedings of the National Academy of Sciences 119 (9), e2117198119, 2022 | 95 | 2022 |
| SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism M Shi, L Wang, P Fontana, S Vora, Y Zhang, TM Fu, J Lieberman, H Wu BioRxiv, 2020 | 72 | 2020 |
| The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis A Balasubramanian, AY Hsu, L Ghimire, M Tahir, P Devant, P Fontana, ... Science immunology 9 (94), eadn1452, 2024 | 64 | 2024 |
| Structural basis of regulated m7G tRNA modification by METTL1–WDR4 J Li, L Wang, Q Hahn, RP Nowak, T Viennet, EA Orellana, ... Nature 613 (7943), 391-397, 2023 | 62 | 2023 |
| Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes L Robert Hollingsworth, L David, Y Li, AR Griswold, J Ruan, H Sharif, ... Nature communications 12 (1), 189, 2021 | 62 | 2021 |
| Tryptophan promotes morphological and physiological differentiation in Streptomyces coelicolor E Palazzotto, G Renzone, P Fontana, L Botta, A Scaloni, AM Puglia, ... Applied microbiology and biotechnology 99, 10177-10189, 2015 | 30 | 2015 |
| Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling P Fontana, SC Buch-Larsen, O Suyari, R Smith, MJ Suskiewicz, ... Nature Communications 14 (1), 3200, 2023 | 19 | 2023 |
| Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity P Fontana, G Du, Y Zhang, H Zhang, SM Vora, JJ Hu, M Shi, AB Tufan, ... Cell 187 (22), 6165-6181. e22, 2024 | 16 | 2024 |
| Ragulator-Rag and ROS TORment gasdermin D pore formation VG Magupalli, P Fontana, H Wu Trends in immunology 42 (11), 948-950, 2021 | 8 | 2021 |
| Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation G Du, L Zhao, Y Zheng, A Belfetmi, T Cai, B Xu, K Heyninck, ... Cell Research 33 (2), 131-146, 2023 | 7 | 2023 |
| DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation LR Hollingsworth, H Sharif, AR Griswold, P Fontana, J Mintseris, ... bioRxiv, 2020.08. 14.246132, 2020 | 3 | 2020 |
| Novel mode of filament formation in UPA-promoted CARD8 and NLRP1 Inflammasomes LR Hollingsworth, L David, Y Li, AR Griswold, H Sharif, P Fontana, TM Fu, ... bioRxiv, 2020.06. 27.175497, 2020 | 3 | 2020 |
| Data for EMSL Project 51488 from April 2021 I Novikova, L Hollingsworth, H Wu, H Sharif, P Fontana, K Walter, S Lee, ... Pacific Northwest National Laboratory (PNNL), Richland, WA (United States …, 2021 | | 2021 |
