Nomenclature for human glutathione transferases B Mannervik, YC Awasthi, PG Board, JD Hayes, C Di Ilio, B Ketterer, ... Biochemical Journal 282 (Pt 1), 305, 1992 | 930 | 1992 |
Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. K Berhane, M Widersten, Å Engström, JW Kozarich, B Mannervik Proceedings of the National Academy of Sciences 91 (4), 1480-1484, 1994 | 549 | 1994 |
Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative … S Baez, J Segura-Aguilar, M Widersten, AS Johansson, B Mannervik Biochemical Journal 324 (1), 25-28, 1997 | 431 | 1997 |
Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. K Sundberg, AS Johansson, G Stenberg, M Widersten, A Seidel, ... Carcinogenesis 19 (3), 433-436, 1998 | 428 | 1998 |
Deep eutectic solvents (DESs) are viable cosolvents for enzyme-catalyzed epoxide hydrolysis D Lindberg, M de la Fuente Revenga, M Widersten Journal of biotechnology 147 (3-4), 169-171, 2010 | 296 | 2010 |
Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105 AS Johansson, G Stenberg, M Widersten, B Mannervik Journal of molecular biology 278 (3), 687-698, 1998 | 231 | 1998 |
Glutathione conjugation of bay-and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1 K Sundberg, M Widersten, A Seidel, B Mannervik, B Jernström Chemical research in toxicology 10 (11), 1221-1227, 1997 | 157 | 1997 |
Human class Mu glutathione transferases, in particular isoenzyme M2-2, catalyze detoxication of the dopamine metabolite aminochrome J Segura-Aguilar, S Baez, M Widersten, CJ Welch, B Mannervik Journal of Biological Chemistry 272 (9), 5727-5731, 1997 | 151 | 1997 |
Glutathione transferases with novel active sites isolated by phage display from a library of random mutants M Widersten, B Mannervik Journal of molecular biology 250 (2), 115-122, 1995 | 151 | 1995 |
Functional significance of arginine 15 in the active site of human class alpha glutathione transferase A1-1 R Björnestedt, G Stenberg, M Widersten, PG Board, I Sinning, TA Jones, ... Journal of molecular biology 247 (4), 765-773, 1995 | 123 | 1995 |
Heterologous expression of the allelic variant mu-class glutathione transferases μ and ψ M Widersten, WR Pearson, A Engström, B Mannervik Biochemical Journal 276 (2), 519-524, 1991 | 121 | 1991 |
Inhibition of glutathione S‐transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance S Mukanganyama, M Widersten, YS Naik, B Mannervik, JA Hasler International journal of cancer 97 (5), 700-705, 2002 | 119 | 2002 |
Structure–function relationships of epoxide hydrolases and their potential use in biocatalysis M Widersten, A Gurell, D Lindberg Biochimica et Biophysica Acta (BBA)-General Subjects 1800 (3), 316-326, 2010 | 110 | 2010 |
Conjugation of highly reactive aflatoxin B1 exo-8, 9-epoxide catalyzed by rat and human glutathione transferases: estimation of kinetic parameters WW Johnson, YF Ueng, M Widersten, B Mannervik, JD Hayes, PJ Sherratt, ... Biochemistry 36 (11), 3056-3060, 1997 | 100 | 1997 |
Human glutathione transferases: classification, tissue distribution, structure, and functional properties B Mannervik, M Widersten Advances in drug metabolism in man, 407-459, 1995 | 94 | 1995 |
X‐ray structure of potato epoxide hydrolase sheds light on substrate specificity in plant enzymes SL Mowbray, LT Elfström, KM Ahlgren, CE Andersson, M Widersten Protein Science 15 (7), 1628-1637, 2006 | 93 | 2006 |
Involvement of the carboxyl groups of glutathione in the catalytic mechanism of human glutathione transferase A1-1 M Widersten, R Björnestedt, B Mannervik Biochemistry 35 (24), 7731-7742, 1996 | 93 | 1996 |
Differences among human tumor cell lines in the expression of glutathione transferases and other glutathione-linked enzymes VM Castro, M Söderström, I Carlberg, M Widersten, A Platz, B Mannervik Carcinogenesis 11 (9), 1569-1576, 1990 | 93 | 1990 |
A comparison of the enzymatic and physicochemical properties of human glutathione transferase M4-4 and three other human Mu class enzymes KE Comstock, M Widersten, XY Hao, WD Henner, B Mannervik Archives of biochemistry and biophysics 311 (2), 487-495, 1994 | 83 | 1994 |
Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1 M Widersten, RH Kolm, R Björnestedt, B Mannervik Biochemical Journal 285 (2), 377-381, 1992 | 75 | 1992 |