Systemic delivery of tumor-targeting siRNA nanoparticles against an oncogenic LncRNA facilitates effective triple-negative breast cancer therapy AM Vaidya, Z Sun, N Ayat, A Schilb, X Liu, H Jiang, D Sun, J Scheidt, ... Bioconjugate chemistry 30 (3), 907-919, 2019 | 152 | 2019 |
Synthesis and evaluation of pH-sensitive multifunctional lipids for efficient delivery of CRISPR/Cas9 in gene editing D Sun, Z Sun, H Jiang, AM Vaidya, R Xin, NR Ayat, AL Schilb, PL Qiao, ... Bioconjugate Chemistry 30 (3), 667-678, 2018 | 41 | 2018 |
Formulation of biocompatible targeted ECO/siRNA nanoparticles with long-term stability for clinical translation of RNAi NR Ayat, Z Sun, D Sun, M Yin, RC Hall, AM Vaidya, X Liu, AL Schilb, ... nucleic acid therapeutics 29 (4), 195-207, 2019 | 28 | 2019 |
Efficacy of targeted ECO/miR-200c nanoparticles for modulating tumor microenvironment and treating triple negative breast cancer as non-invasively monitored by MR molecular imaging AL Schilb, NR Ayat, AM Vaidya, LM Hertz, RC Hall, JH Scheidt, D Sun, ... Pharmaceutical Research 38 (8), 1405-1418, 2021 | 27 | 2021 |
Effective gene therapy of Stargardt disease with PEG-ECO/pGRK1-ABCA4-S/MAR nanoparticles D Sun, W Sun, SQ Gao, J Lehrer, A Naderi, C Wei, S Lee, AL Schilb, ... Molecular Therapy-Nucleic Acids 29, 823-835, 2022 | 24 | 2022 |
Formulation and efficacy of ECO/pRHO-ABCA4-SV40 nanoparticles for nonviral gene therapy of Stargardt disease in a mouse model D Sun, W Sun, SQ Gao, C Wei, A Naderi, AL Schilb, J Scheidt, S Lee, ... Journal of Controlled Release 330, 329-340, 2021 | 20 | 2021 |
Regulating oncogenic LncRNA DANCR with targeted ECO/siRNA nanoparticles for non-small cell lung cancer therapy C Nicolescu, A Vaidya, A Schilb, ZR Lu ACS omega 7 (26), 22743-22753, 2022 | 13 | 2022 |
Evaluating dual-targeted ECO/siRNA nanoparticles against an oncogenic lncRNA for triple negative breast cancer therapy with magnetic resonance molecular imaging C Nicolescu, A Schilb, J Kim, D Sun, R Hall, S Gao, H Gilmore, ... Chemical & Biomedical Imaging 1 (5), 461-470, 2023 | 12 | 2023 |
Optimization of synthesis of the amino lipid ECO for effective delivery of nucleic acids AL Schilb, JH Scheidt, AM Vaidya, Z Sun, D Sun, S Lee, ZR Lu Pharmaceuticals 14 (10), 1016, 2021 | 6 | 2021 |
Role of eIF4E on epithelial‐mesenchymal transition, invasion, and chemoresistance of prostate cancer cells X Liu, AM Vaidya, D Sun, Y Zhang, N Ayat, A Schilb, ZR Lu Cancer Communications 40 (2-3), 126, 2020 | 6 | 2020 |
Optimization of Non-Viral Gene Delivery System for Image-Guided Therapy for Triple Negative Breast Cancer AL Schilb Case Western Reserve University, 2021 | | 2021 |