Gene silencing by microRNAs: contributions of translational repression and mRNA decay E Huntzinger, E Izaurralde Nature Reviews Genetics 12 (2), 99-110, 2011 | 2985 | 2011 |
Getting to the root of miRNA-mediated gene silencing A Eulalio, E Huntzinger, E Izaurralde Cell 132 (1), 9-14, 2008 | 1410 | 2008 |
Deadenylation is a widespread effect of miRNA regulation A Eulalio, E Huntzinger, T Nishihara, J Rehwinkel, M Fauser, E Izaurralde Rna 15 (1), 21-32, 2009 | 622 | 2009 |
Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism S Boisset, T Geissmann, E Huntzinger, P Fechter, N Bendridi, ... Genes & development 21 (11), 1353-1366, 2007 | 613 | 2007 |
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay A Eulalio, E Huntzinger, E Izaurralde Nature structural & molecular biology 15 (4), 346-353, 2008 | 568 | 2008 |
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets JE Braun, E Huntzinger, M Fauser, E Izaurralde Molecular cell 44 (1), 120-133, 2011 | 517 | 2011 |
Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression E Huntzinger, S Boisset, C Saveanu, Y Benito, T Geissmann, A Namane, ... The EMBO journal 24 (4), 824-835, 2005 | 447 | 2005 |
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing A Eulalio, J Rehwinkel, M Stricker, E Huntzinger, SF Yang, T Doerks, ... Genes & development 21 (20), 2558-2570, 2007 | 440 | 2007 |
SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan E Huntzinger, I Kashima, M Fauser, J Saulière, E Izaurralde Rna 14 (12), 2609-2617, 2008 | 380 | 2008 |
The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release L Zekri, E Huntzinger, S Heimstädt, E Izaurralde Molecular and cellular biology 29 (23), 6220-6231, 2009 | 266 | 2009 |
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5′ exonucleolytic degradation JE Braun, V Truffault, A Boland, E Huntzinger, CT Chang, G Haas, ... Nature structural & molecular biology 19 (12), 1324-1331, 2012 | 251 | 2012 |
Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival N Wittkopp, E Huntzinger, C Weiler, J Saulière, S Schmidt, M Sonawane, ... Molecular and Cellular Biology, 2009 | 228 | 2009 |
The poly (A) binding protein Hfq protects RNA from RNase E and exoribonucleolytic degradation M Folichon, V Arluison, O Pellegrini, E Huntzinger, P Régnier, E Hajnsdorf Nucleic acids research 31 (24), 7302-7310, 2003 | 218 | 2003 |
Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein A Boland, E Huntzinger, S Schmidt, E Izaurralde, O Weichenrieder Proceedings of the National Academy of Sciences 108 (26), 10466-10471, 2011 | 173 | 2011 |
The role of GW182 proteins in miRNA-mediated gene silencing JE Braun, E Huntzinger, E Izaurralde Ten years of progress in GW/P body research, 147-163, 2013 | 171 | 2013 |
The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets E Huntzinger, D Kuzuoğlu-Öztürk, JE Braun, A Eulalio, L Wohlbold, ... Nucleic acids research 41 (2), 978-994, 2013 | 160 | 2013 |
Two PABPC1‐binding sites in GW182 proteins promote miRNA‐mediated gene silencing E Huntzinger, JE Braun, S Heimstädt, L Zekri, E Izaurralde The EMBO journal 29 (24), 4146-4160, 2010 | 150 | 2010 |
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex AP Petit, L Wohlbold, P Bawankar, E Huntzinger, S Schmidt, E Izaurralde, ... Nucleic acids research 40 (21), 11058-11072, 2012 | 149 | 2012 |
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins M Christie, A Boland, E Huntzinger, O Weichenrieder, E Izaurralde Molecular cell 51 (3), 360-373, 2013 | 135 | 2013 |
Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of deja vu F Tritschler, E Huntzinger, E Izaurralde Nature reviews Molecular cell biology 11 (5), 379-384, 2010 | 118 | 2010 |