A highly efficient human pluripotent stem cell microglia model displays a neuronal-co-culture-specific expression profile and inflammatory response W Haenseler, SN Sansom, J Buchrieser, SE Newey, CS Moore, ... Stem cell reports 8 (6), 1727-1742, 2017 | 529 | 2017 |
Mutations in DEPDC5 cause familial focal epilepsy with variable foci LM Dibbens, B De Vries, S Donatello, SE Heron, BL Hodgson, ... Nature genetics 45 (5), 546-551, 2013 | 415 | 2013 |
Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: a multi-site omics study V Volpato, J Smith, C Sandor, JS Ried, A Baud, A Handel, SE Newey, ... Stem cell reports 11 (4), 897-911, 2018 | 176 | 2018 |
Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia A Hick, M Wattenhofer-Donzé, S Chintawar, P Tropel, JP Simard, ... Disease models & mechanisms 6 (3), 608-621, 2013 | 176 | 2013 |
Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host J Jäderstad, LM Jäderstad, J Li, S Chintawar, C Salto, M Pandolfo, ... Proceedings of the National Academy of Sciences 107 (11), 5184-5189, 2010 | 161 | 2010 |
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics AE Handel, S Chintawar, T Lalic, E Whiteley, J Vowles, A Giustacchini, ... Human molecular genetics 25 (5), 989-1000, 2016 | 124 | 2016 |
Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model S Chintawar, R Hourez, A Ravella, D Gall, D Orduz, M Rai, DP Bishop, ... Journal of Neuroscience 29 (42), 13126-13135, 2009 | 91 | 2009 |
Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia M Igoillo-Esteve, E Gurgul-Convey, A Hu, ... Human molecular genetics 24 (8), 2274-2286, 2015 | 74 | 2015 |
A causal role for TRESK loss of function in migraine mechanisms P Pettingill, GA Weir, T Wei, Y Wu, G Flower, T Lalic, A Handel, G Duggal, ... Brain 142 (12), 3852-3867, 2019 | 63 | 2019 |
Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers HH Jarosz-Griffiths, NJ Corbett, HA Rowland, K Fisher, AC Jones, J Baron, ... Journal of Biological Chemistry 294 (17), 7085-7097, 2019 | 57 | 2019 |
Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia M Igoillo-Esteve, AF Oliveira, C Cosentino, F Fantuzzi, C Demarez, ... JCI insight 5 (2), e134221, 2020 | 50 | 2020 |
Blood–brain barrier promotes differentiation of human fetal neural precursor cells S Chintawar, R Cayrol, J Antel, M Pandolfo, A Prat Stem cells 27 (4), 838-846, 2009 | 48 | 2009 |
Neurovascular dysfunction in dementia–human cellular models and molecular mechanisms I Parkes, S Chintawar, MZ Cader Clinical Science 132 (3), 399-418, 2018 | 35 | 2018 |
Gene set enrichment analysis reveals several globally affected pathways due to SKI-1/S1P inhibition in HepG2 cells A De Windt, M Rai, L Bernier, K Thelen, J Soini, C Lefebvre, S Chintawar, ... DNA and cell biology 26 (11), 765-772, 2007 | 12 | 2007 |
Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s Ataxia. Dis. Model. Mech. 6 (3), 608–621 A Hick, M Wattenhofer-Donze, S Chintawar, P Tropel, JP Simard, ... | 8 | 2013 |
Induced pluripotent stem cell derived neurons and cardiomyocytes as a model for mitochondrial defects in Friedreich’s ataxia A Hick, M Wattenhofer-Donze, S Chintawar, P Tropel, JP Simard, ... Dis. Model. Mech 7 (10.1242), 2012 | 8 | 2012 |
Utility of human stem cells for drug discovery S Chintawar, M Graf, Z Cader | 2 | 2014 |
Stereological quantification of Cerebellar Purkinje cells: literature review and description of a variation of the physical disector method adapted to confocal laser microscopy S Chintawar, F Fregnan, M Pandolfo, S Geuna NeuroQuantology 10 (1), 125-132, 2012 | 2 | 2012 |
An Induced Pluripotent Stem Cell Model for Friedreich's Ataxia (IN8-1.007) M Pandolfo, S Chintawar, M Wattenhofer-Donze, H Puccio Neurology 78 (1_supplement), IN8-1.007-IN8-1.007, 2012 | 1 | 2012 |
THREE DIMENSIONAL ORGANOID MODELLING TO INDUCE DIRECTED DIFFERENTIATION OF HUMAN INDUCED PLURIPOTENT STEM CELLS TOWARDS A PEPTIDERGIC TRIGEMINAL NEURONAL FATE G Duggal, P Pettingill, S Chintawar, Z Cader CEPHALALGIA 36, 137-138, 2016 | | 2016 |