Metallo-β-lactamases: novel weaponry for antibiotic resistance in bacteria MW Crowder, J Spencer, AJ Vila Accounts of chemical research 39 (10), 721-728, 2006 | 482 | 2006 |
Hydrolysis of phosphate monoesters: a biological problem with multiple chemical solutions JB Vincent, MW Crowder, BA Averill Trends in biochemical sciences 17 (3), 105-110, 1992 | 482 | 1992 |
Overexpression, Purification, and Characterization of the Cloned Metallo-β-Lactamase L1 fromStenotrophomonas maltophilia MW Crowder, TR Walsh, L Banovic, M Pettit, J Spencer Antimicrobial agents and chemotherapy 42 (4), 921-926, 1998 | 234 | 1998 |
Dipicolinic acid derivatives as inhibitors of New Delhi metallo-β-lactamase-1 AY Chen, PW Thomas, AC Stewart, A Bergstrom, Z Cheng, C Miller, ... Journal of medicinal chemistry 60 (17), 7267-7283, 2017 | 157 | 2017 |
The continuing challenge of metallo-β-lactamase inhibition: mechanism matters LC Ju, Z Cheng, W Fast, RA Bonomo, MW Crowder Trends in pharmacological sciences 39 (7), 635-647, 2018 | 150 | 2018 |
Kinetic mechanism of metallo-β-lactamase L1 from Stenotrophomonas maltophilia S McManus-Munoz, MW Crowder Biochemistry 38 (5), 1547-1553, 1999 | 141 | 1999 |
A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases MN Lisa, AR Palacios, M Aitha, MM González, DM Moreno, MW Crowder, ... Nature communications 8 (1), 538, 2017 | 135 | 2017 |
Characterization of the metal-binding sites of the β-lactamase from Bacteroides fragilis MW Crowder, Z Wang, SL Franklin, EP Zovinka, SJ Benkovic Biochemistry 35 (37), 12126-12132, 1996 | 135 | 1996 |
Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli LA Yatsunyk, JA Easton, LR Kim, SA Sugarbaker, B Bennett, RM Breece, ... JBIC Journal of Biological Inorganic Chemistry 13, 271-288, 2008 | 131 | 2008 |
Purple acid phosphatase: a diiron enzyme that catalyzes a direct phospho group transfer to water EG Mueller, MW Crowder, BA Averill, JR Knowles Journal of the American Chemical Society 115 (7), 2974-2975, 1993 | 131 | 1993 |
Mechanistic and spectroscopic studies of metallo-β-lactamase NDM-1 H Yang, M Aitha, AM Hetrick, TK Richmond, DL Tierney, MW Crowder Biochemistry 51 (18), 3839-3847, 2012 | 126 | 2012 |
Structural studies on a mitochondrial glyoxalase II GPK Marasinghe, IM Sander, B Bennett, G Periyannan, KW Yang, ... Journal of Biological Chemistry 280 (49), 40668-40675, 2005 | 112 | 2005 |
Arabidopsis glyoxalase II contains a zinc/iron binuclear metal center that is essential for substrate binding and catalysis* 210 TM Zang, DA Hollman, PA Crawford, MW Crowder, CA Makaroff Journal of Biological Chemistry 276 (7), 4788-4795, 2001 | 112 | 2001 |
Flexible metal binding of the metallo-β-lactamase domain: glyoxalase II incorporates iron, manganese, and zinc in vivo O Schilling, N Wenzel, M Naylor, A Vogel, M Crowder, C Makaroff, ... Biochemistry 42 (40), 11777-11786, 2003 | 105 | 2003 |
Mutational analysis of metallo-β-lactamase CcrA from Bacteroides fragilis MP Yanchak, RA Taylor, MW Crowder Biochemistry 39 (37), 11330-11339, 2000 | 101 | 2000 |
Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: effects of NDM mutations on stability, zinc affinity, and mono-zinc activity Z Cheng, PW Thomas, L Ju, A Bergstrom, K Mason, D Clayton, C Miller, ... Journal of Biological Chemistry 293 (32), 12606-12618, 2018 | 98 | 2018 |
Direct evidence that the reaction intermediate of metallo-β-lactamase L1 is metal bound JD Garrity, B Bennett, MW Crowder Biochemistry 44 (3), 1078-1087, 2005 | 97 | 2005 |
Role of the Zn1 and Zn2 sites in Metallo-β-lactamase L1 Z Hu, G Periyannan, B Bennett, MW Crowder Journal of the American Chemical Society 130 (43), 14207-14216, 2008 | 94 | 2008 |
Spectroscopic and kinetics studies of a high-salt-stabilized form of the purple acid phosphatase from bovine spleen JB Vincent, MW Crowder, BA Averill Biochemistry 30 (12), 3025-3034, 1991 | 92 | 1991 |
Metal binding Asp-120 in metallo-β-lactamase L1 from Stenotrophomonas maltophilia plays a crucial role in catalysis JD Garrity, AL Carenbauer, LR Herron, MW Crowder Journal of Biological Chemistry 279 (2), 920-927, 2004 | 90 | 2004 |