Lysosome-targeting chimaeras for degradation of extracellular proteins SM Banik, K Pedram, S Wisnovsky, G Ahn, NM Riley, CR Bertozzi Nature 584 (7820), 291-297, 2020 | 758 | 2020 |
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation G Ahn, SM Banik, CL Miller, NM Riley, JR Cochran, CR Bertozzi Nature Chemical Biology 17 (9), 937-946, 2021 | 350 | 2021 |
Targeted glycan degradation potentiates the anticancer immune response in vivo MA Gray, MA Stanczak, NR Mantuano, H Xiao, JFA Pijnenborg, ... Nature chemical biology 16 (12), 1376-1384, 2020 | 277 | 2020 |
Degradation from the outside in: Targeting extracellular and membrane proteins for degradation through the endolysosomal pathway G Ahn, SM Banik, CR Bertozzi Cell chemical biology 28 (7), 1072-1080, 2021 | 53 | 2021 |
Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras G Ahn, NM Riley, RA Kamber, S Wisnovsky, S Moncayo von Hase, ... Science 382 (6668), eadf6249, 2023 | 52 | 2023 |
Toward Point-of-Care Detection of Mycobacterium tuberculosis: A Brighter Solvatochromic Probe Detects Mycobacteria within Minutes M Kamariza, SGL Keyser, A Utz, BD Knapp, C Ealand, G Ahn, ... JACS Au 1 (9), 1368-1379, 2021 | 36 | 2021 |
Overexpression of a three-gene conidial pigment biosynthetic pathway in Aspergillus nidulans reveals the first NRPS known to acetylate tryptophan CT Sung, SL Chang, R Entwistle, G Ahn, TS Lin, V Petrova, HH Yeh, ... Fungal Genetics and Biology 101, 1-6, 2017 | 30 | 2017 |
H–D exchange in deuterated trifluoroacetic acid via ligand-directed NHC–palladium catalysis: a powerful method for deuteration of aromatic ketones, amides, and amino acids R Giles, G Ahn, KW Jung Tetrahedron letters 56 (45), 6231-6235, 2015 | 27 | 2015 |
An Aspergillus nidulans Platform for the Complete Cluster Refactoring and Total Biosynthesis of Fungal Natural Products YM Chiang, TS Lin, SL Chang, G Ahn, CCC Wang ACS Synthetic Biology 10 (1), 173-182, 2020 | 19 | 2020 |
Targeted desialylation overcomes glyco-immune checkpoints and potentiates the anticancer immune response in vivo M Gray, MA Stanczak, H Xiao, JFA Pijnenborg, NR Mantuano, SA Malaker, ... | 11 | 2019 |
Lysosome targeting chimeras (LYTACs) that engage a liver-specific asialoglycoprotein receptor for targeted protein degradation G Ahn, S Banik, CL Miller, N Riley, JR Cochran, C Bertozzi | 9 | 2020 |
Designed endocytosis-inducing proteins degrade targets and amplify signals B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, ... Nature, 1-9, 2024 | 6 | 2024 |
Designed endocytosis-triggering proteins mediate targeted degradation B Huang, M Abedi, G Ahn, B Coventry, I Sappington, R Wang, ... BioRxiv, 2023 | 6 | 2023 |
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists M Glögl, A Krishnakumar, RJ Ragotte, I Goreshnik, B Coventry, AK Bera, ... Science 386 (6726), 1154-1161, 2024 | 5 | 2024 |
Towards Mycobacterium tuberculosis detection at the point-of-care: a brighter solvatochromic probe permits the detection of mycobacteria within minutes M Kamariza, SGL Keyser, A Utz, BD Knapp, G Ahn, CJ Cambier, T Chen, ... bioRxiv, 2020.05. 29.124008, 2020 | 4 | 2020 |
Improved protein binder design using beta-pairing targeted RFdiffusion I Sappington, M Toul, DS Lee, SA Robinson, I Goreshnik, C McCurdy, ... bioRxiv, 2024.10. 11.617496, 2024 | 2 | 2024 |
Bifunctional Molecules for Lysosomal Targeting and Related Compositions and Methods C Bertozzi, S Banik, K Pedram, G Ahn US Patent App. 17/311,779, 2022 | 1 | 2022 |
Improved protein binder design using beta-pairing targeted RFdiffusion D Baker, I Sappington, M Toul, D Lee, S Robinson, I Goreshnik, ... | | 2025 |
LYTAC targeting galectin-1 to enhance radioimmunotherapy of cancers in the upper aerodigestive tract Y Jiang, G Ahn, M Rahman, H Cao, C Bertozzi, Q Le Cancer Research 84 (6_Supplement), 3880-3880, 2024 | | 2024 |
Bifunctional Molecules for Lysosomal Targeting and Related Compositions and Methods CR Bertozzi, S Banik, K Pedram, G Ahn US Patent App. 18/244,121, 2023 | | 2023 |