Frank von Delft

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Finansman sağlayan kuruluşun getirdiği zorunluluğa dayalı olarak

Katkıda bulunan yazarlar

Opher GileadiSGC, Karolinska Instituteki.se üzerinde doğrulanmış e-posta adresine sahip
Brian MarsdenCentre for Medicines Discovery & Centre for Human Genetics, NDM, University of Oxfordcmd.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Tobias KrojerMAX IV Laboratorymaxiv.lu.se üzerinde doğrulanmış e-posta adresine sahip
Wen Hwa LeeAction Against AMD, SGC and University of Oxfordactionagainstamd.org üzerinde doğrulanmış e-posta adresine sahip
Stefan KnappUniversity of Frankfurtpharmchem.uni-frankfurt.de üzerinde doğrulanmış e-posta adresine sahip
Ashley PikeCentre for Medicines Discovery - University of Oxfordcmd.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Tom L BlundellEmeritus Professor of Biochemistry, University of Cambridgecam.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Patrick M CollinsExscientiaexscientia.co.uk üzerinde doğrulanmış e-posta adresine sahip
Oleg FedorovUniversity of Oxfordcmd.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Joao Renato Carvalho MunizAssociate Professor, Physics Institute of Sao Carlos, University of Sao Pauloifsc.usp.br üzerinde doğrulanmış e-posta adresine sahip
Anthony BradleyUniversity of Liverpoolliverpool.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Charlotte DeaneProfessor of Structural Bioinformatics, Oxford Universitystats.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Nicholas M PearceAssistant Professor, Linköping Universityliu.se üzerinde doğrulanmış e-posta adresine sahip
Frank NiesenJohnson & Johnsonits.jnj.com üzerinde doğrulanmış e-posta adresine sahip
Grazyna KochanTeam Leadernavarra.es üzerinde doğrulanmış e-posta adresine sahip
Panagis FilippakopoulosAssociate Professor, Oxford Universitysgc.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Cheryl ArrowsmithSenior Scientist, Princess Margaret Cancer Centre & Professor of Medical Biophysics, University of Torontouhnres.utoronto.ca üzerinde doğrulanmış e-posta adresine sahip
Declan A. DoyleUniversity of Southamptonsoton.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Michael McDonoughAtomic Resolution Consulting ABatomic-resolution.com üzerinde doğrulanmış e-posta adresine sahip
Prof. Alison G. SmithDept of Plant Sciences, University of Cambridgecam.ac.uk üzerinde doğrulanmış e-posta adresine sahip

Takip et

Frank von Delft

Principal Investigator: Protein Crystallography, SGC, Oxford University

sgc.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip

Protein Crystallography Fragment-based approaches Crystallographic Computing Synchrotron radiation Robotics


Başlık Alıntılara göre sırala Yıla göre sırala Başlığa göre sırala	Alıntı yapanlar Alıntı yapanlar	Yıl
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin L Pellegrini, DF Burke, F Von Delft, B Mulloy, TL Blundell Nature 407 (6807), 1029-1034, 2000	946	2000
CCP4i2: the new graphical user interface to the CCP4 program suite L Potterton, J Agirre, C Ballard, K Cowtan, E Dodson, PR Evans, ... Acta Crystallographica Section D: Structural Biology 74 (2), 68-84, 2018	514	2018
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease A Douangamath, D Fearon, P Gehrtz, T Krojer, P Lukacik, CD Owen, ... Nature communications 11 (1), 5047, 2020	512	2020
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity SS Ng, KL Kavanagh, MA McDonough, D Butler, ES Pilka, BMR Lienard, ... Nature 448 (7149), 87-91, 2007	358	2007
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ... Journal of Biological Chemistry 288 (11), 7803-7814, 2013	321	2013
Structure of the CaMKIIδ/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation P Rellos, ACW Pike, FH Niesen, E Salah, WH Lee, F Von Delft, S Knapp PLoS biology 8 (7), e1000426, 2010	294	2010
Rapid covalent-probe discovery by electrophile-fragment screening E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ... Journal of the American Chemical Society 141 (22), 8951-8968, 2019	291	2019
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ... Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013	285	2013
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming G Kochan, T Krojer, D Harvey, R Fischer, L Chen, M Vollmar, F von Delft, ... Proceedings of the National Academy of Sciences 108 (19), 7745-7750, 2011	285	2011
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density NM Pearce, T Krojer, AR Bradley, P Collins, RP Nowak, R Talon, ... Nature communications 8 (1), 15123, 2017	269	2017
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022	214	2022
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva A Chaikuad, I Alfano, G Kerr, CE Sanvitale, JH Boergermann, JT Triffitt, ... Journal of Biological Chemistry 287 (44), 36990-36998, 2012	207	2012
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase JA Newman, A Douangamath, S Yadzani, Y Yosaatmadja, A Aimon, ... Nature Communications 12 (1), 4848, 2021	192	2021
A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP (2), an atypical bromodomain OB Cox, T Krojer, P Collins, O Monteiro, R Talon, A Bradley, O Fedorov, ... Chemical science 7 (3), 2322-2330, 2016	191	2016
Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases D Chen, M Vollmar, MN Rossi, C Phillips, R Kraehenbuehl, D Slade, ... Journal of Biological Chemistry 286 (15), 13261-13271, 2011	191	2011
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ... Journal of medicinal chemistry 55 (14), 6639-6643, 2012	172	2012
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering DA Keedy, ZB Hill, JT Biel, E Kang, TJ Rettenmaier, J Brandao-Neto, ... Elife 7, e36307, 2018	162	2018
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021	157	2021
The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity C Johansson, AK Roos, SJ Montano, R Sengupta, P Filippakopoulos, ... Biochemical Journal 433 (2), 303-311, 2011	153	2011
Crystal structure of aspartate decarboxylase at 2.2 Å resolution provides evidence for an ester in protein self–processing A Albert, V Dhanaraj, U Genschel, G Khan, MK Ramjee, R Pulido, ... Nature structural biology 5 (4), 289-293, 1998	145	1998

Sistem, işlemi şu anda gerçekleştiremiyor. Daha sonra yeniden deneyin.

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