| Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells ME Pipkin, JA Sacks, F Cruz-Guilloty, MG Lichtenheld, MJ Bevan, A Rao Immunity 32 (1), 79-90, 2010 | 980 | 2010 |
| The transcription factor NFAT promotes exhaustion of activated CD8+ T cells GJ Martinez, RM Pereira, T Äijö, EY Kim, F Marangoni, ME Pipkin, ... Immunity 42 (2), 265-278, 2015 | 793 | 2015 |
| Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours JJ Milner, C Toma, B Yu, K Zhang, K Omilusik, AT Phan, D Wang, ... Nature 552 (7684), 253-257, 2017 | 626 | 2017 |
| Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs F Cruz-Guilloty, ME Pipkin, IM Djuretic, D Levanon, J Lotem, ... Journal of Experimental Medicine 206 (1), 51-59, 2009 | 580 | 2009 |
| Delivering the kiss of death: progress on understanding how perforin works ME Pipkin, J Lieberman Current opinion in immunology 19 (3), 301-308, 2007 | 366 | 2007 |
| Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation B Yu, K Zhang, JJ Milner, C Toma, R Chen, JP Scott-Browne, RM Pereira, ... Nature immunology 18 (5), 573-582, 2017 | 239 | 2017 |
| The transcription factor Runx3 establishes chromatin accessibility of cis-regulatory landscapes that drive memory cytotoxic T lymphocyte formation D Wang, H Diao, AJ Getzler, W Rogal, MA Frederick, J Milner, B Yu, ... Immunity 48 (4), 659-674. e6, 2018 | 180 | 2018 |
| DNA methylation and chromatin structure regulate T cell perforin gene expression Q Lu, A Wu, D Ray, C Deng, J Attwood, S Hanash, M Pipkin, ... The Journal of Immunology 170 (10), 5124-5132, 2003 | 156 | 2003 |
| Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits J Choi, H Diao, CE Faliti, J Truong, M Rossi, S Bélanger, B Yu, ... Nature immunology 21 (7), 777-789, 2020 | 140 | 2020 |
| In vivo RNA interference screens identify regulators of antiviral CD4+ and CD8+ T cell differentiation R Chen, S Belanger, MA Frederick, B Li, RJ Johnston, N Xiao, YC Liu, ... Immunity 41 (2), 325-338, 2014 | 131 | 2014 |
| MicroRNA-221–222 regulate the cell cycle in mast cells RJ Mayoral, ME Pipkin, M Pachkov, E van Nimwegen, A Rao, S Monticelli The Journal of Immunology 182 (1), 433-445, 2009 | 121 | 2009 |
| MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation S Trifari, ME Pipkin, HS Bandukwala, T Äijö, J Bassein, R Chen, ... Proceedings of the National Academy of Sciences 110 (46), 18608-18613, 2013 | 110 | 2013 |
| The transcriptional control of the perforin locus ME Pipkin, A Rao, MG Lichtenheld Immunological reviews 235 (1), 55-72, 2010 | 97 | 2010 |
| CAR directs T cell adaptation to bile acids in the small intestine ML Chen, X Huang, H Wang, C Hegner, Y Liu, J Shang, A Eliason, H Diao, ... Nature 593 (7857), 147-151, 2021 | 61 | 2021 |
| YAP-mediated recruitment of YY1 and EZH2 represses transcription of key cell-cycle regulators S Hoxha, A Shepard, S Troutman, H Diao, JR Doherty, M Janiszewska, ... Cancer research 80 (12), 2512-2522, 2020 | 60 | 2020 |
| Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development MR Müller, Y Sasaki, I Stevanovic, ED Lamperti, S Ghosh, S Sharma, ... Proceedings of the National Academy of Sciences 106 (17), 7034-7039, 2009 | 58 | 2009 |
| Chromosome transfer activates and delineates a locus control region for perforin ME Pipkin, B Ljutic, F Cruz-Guilloty, M Nouzova, A Rao, ... Immunity 26 (1), 29-41, 2007 | 46 | 2007 |
| Physiological expression and function of the MDR1 transporter in cytotoxic T lymphocytes ML Chen, A Sun, W Cao, A Eliason, KM Mendez, AJ Getzler, S Tsuda, ... Journal of Experimental Medicine 217 (5), e20191388, 2020 | 38 | 2020 |
| In vivo RNAi screens: concepts and applications S Crotty, ME Pipkin Trends in immunology 36 (5), 315-322, 2015 | 31 | 2015 |
| Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection JJ Milner, C Toma, S Quon, K Omilusik, NE Scharping, A Dey, ... Journal of Experimental Medicine 218 (8), 2021 | 29 | 2021 |
