RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1 IA Elcheva, T Wood, K Chiarolanzio, B Chim, M Wong, V Singh, ... Leukemia 34 (5), 1354-1363, 2020 | 138 | 2020 |
Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target GK Azad, V Singh, P Mandal, P Singh, U Golla, S Baranwal, S Chauhan, ... FEBS open bio 4, 77-89, 2014 | 93 | 2014 |
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability AS Ganapathy, K Saha, E Suchanec, V Singh, A Verma, G Yochum, ... Autophagy 18 (9), 2086-2103, 2022 | 58 | 2022 |
Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells N Wallis, F Oberman, K Shurrush, N Germain, G Greenwald, T Gershon, ... RNA biology 19 (1), 26-43, 2022 | 55 | 2022 |
The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression V Singh, CP Gowda, V Singh, AS Ganapathy, DM Karamchandani, ... Journal of Biological Chemistry 295 (25), 8602-8612, 2020 | 41 | 2020 |
Sen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in Saccharomyces cerevisiae SK Sariki, PK Sahu, U Golla, V Singh, GK Azad, RS Tomar The FEBS journal 283 (22), 4056-4083, 2016 | 39 | 2016 |
Depletion of Cellular Iron by Curcumin Leads to Alteration in Histone Acetylation and Degradation of Sml1p in Saccharomyces cerevisiae GK Azad, V Singh, U Golla, RS Tomar PloS one 8 (3), e59003, 2013 | 36 | 2013 |
Anti-cancer drug KP1019 modulates epigenetics and induces DNA damage response in Saccharomyces cerevisiae V Singh, GK Azad, P Mandal, MA Reddy, RS Tomar FEBS letters 588 (6), 1044-1052, 2014 | 33 | 2014 |
Flocculation of Saccharomyces cerevisiae is dependent on activation of Slt2 and Rlm1 regulated by the cell wall integrity pathway SK Sariki, R Kumawat, V Singh, RS Tomar Molecular microbiology 112 (4), 1350-1369, 2019 | 30 | 2019 |
Sen1p Contributes to Genomic Integrity by Regulating Expression of Ribonucleotide Reductase 1 (RNR1) in Saccharomyces cerevisiae U Golla, V Singh, GK Azad, P Singh, N Verma, P Mandal, S Chauhan, ... PloS one 8 (5), e64798, 2013 | 27 | 2013 |
Assessment of the Biological Pathways Targeted by Isocyanate Using N-Succinimidyl N-Methylcarbamate in Budding Yeast Saccharomyces cerevisiae GK Azad, V Singh, RS Tomar PLoS One 9 (3), e92993, 2014 | 24 | 2014 |
Anti-cancer drug KP1019 induces Hog1 phosphorylation and protein ubiquitylation in Saccharomyces cerevisiae V Singh, GK Azad, A Reddy, S Baranwal, RS Tomar European journal of pharmacology 736, 77-85, 2014 | 23 | 2014 |
Signaling of chloroquine-induced stress in the yeast Saccharomyces cerevisiae requires the Hog1 and Slt2 mitogen-activated protein kinase pathways S Baranwal, GK Azad, V Singh, RS Tomar Antimicrobial Agents and Chemotherapy 58 (9), 5552-5566, 2014 | 20 | 2014 |
IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis VSS Mayura R Dhamdhere, Chethana P Gowda, Vikash Singh, Zhenqiu Liu ... Oncogene, 2023 | 17 | 2023 |
Flocculation in Saccharomyces cerevisiae is regulated by RNA/DNA helicase Sen1p V Singh, GK Azad, SK Sariki, RS Tomar FEBS letters 589 (20), 3165-3174, 2015 | 17 | 2015 |
Mitogen-activated protein kinase Hog1 is activated in response to curcumin exposure in the budding yeast Saccharomyces cerevisiae GK Azad, V Singh, MJ Thakare, S Baranwal, RS Tomar BMC microbiology 14 (1), 1-11, 2014 | 15 | 2014 |
The transcription factor Rap1p is required for tolerance to cell-wall perturbing agents and for cell-wall maintenance in Saccharomyces cerevisiae GK Azad, V Singh, S Baranwal, MJ Thakare, RS Tomar FEBS letters 589 (1), 59-67, 2015 | 10 | 2015 |
Development of a specific and potent IGF2BP1 inhibitor: A promising therapeutic agent for IGF2BP1-expressing cancers A Singh, V Singh, N Wallis, G Abis, F Oberman, T Wood, M Dhamdhere, ... European Journal of Medicinal Chemistry, 115940, 2023 | 9 | 2023 |
Epigenetics: role of histone proteases in cellular functions and diseases P Mandal, N Verma, GK Azad, V Singh, U Golla, RS Tomar Molecular mechanisms and physiology of disease, 113-126, 2014 | 7 | 2014 |
Global role of IGF2BP1 in controlling the expression of Wnt/β-catenin-regulated genes in colorectal cancer cells V Singh, V Walter, I Elcheva, YI Kawasawa, VS Spiegelman Frontiers in Cell and Developmental Biology 11, 2023 | 5 | 2023 |