A cellular hierarchy in melanoma uncouples growth and metastasis P Karras, I Bordeu, J Pozniak, A Nowosad, C Pazzi, N Van Raemdonck, ... Nature 610 (7930), 190-198, 2022 | 156 | 2022 |
CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours B Kruse, AC Buzzai, N Shridhar, AD Braun, S Gellert, K Knauth, J Pozniak, ... Nature 618 (7967), 1033-1040, 2023 | 152 | 2023 |
Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors T Wrzesiński, M Szelag, WA Cieślikowski, A Ida, R Giles, E Zodro, ... BMC cancer 15, 1-18, 2015 | 108 | 2015 |
Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma O Marin-Bejar, A Rogiers, M Dewaele, J Femel, P Karras, J Pozniak, ... Cancer Cell 39 (8), 1135-1149. e8, 2021 | 107 | 2021 |
Vitamin D–VDR signaling inhibits Wnt/β-catenin–mediated melanoma progression and promotes antitumor immunity S Muralidhar, A Filia, J Nsengimana, J Poźniak, SJ O'Shea, JM Diaz, ... Cancer research 79 (23), 5986-5998, 2019 | 104 | 2019 |
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas J Nsengimana, J Laye, A Filia, S O’Shea, S Muralidhar, J Poźniak, ... The Journal of clinical investigation 128 (5), 2048-2063, 2018 | 95 | 2018 |
A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma J Pozniak, D Pedri, E Landeloos, Y Van Herck, A Antoranz, ... Cell 187 (1), 166-183. e25, 2024 | 61 | 2024 |
Gain-of-function genetic alterations of G9a drive oncogenesis S Kato, QY Weng, ML Insco, KY Chen, S Muralidhar, J Pozniak, JMS Diaz, ... Cancer discovery 10 (7), 980-997, 2020 | 59 | 2020 |
Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma Cancer Research, 2019 | 58 | 2019 |
Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach R Metri, A Mohan, J Nsengimana, J Pozniak, C Molina-Paris, ... Scientific reports 7 (1), 17314, 2017 | 43 | 2017 |
Transcriptomic analysis reveals prognostic molecular signatures of stage I melanoma R Thakur, JP Laye, M Lauss, JMS Diaz, SJ O'Shea, J Poźniak, A Filia, ... Clinical Cancer Research 25 (24), 7424-7435, 2019 | 40 | 2019 |
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity P Ho, JC Melms, M Rogava, CJ Frangieh, J Poźniak, SB Shah, Z Walsh, ... Cancer cell 41 (7), 1207-1221. e12, 2023 | 32 | 2023 |
Siah2 control of T-regulatory cells limits anti-tumor immunity M Scortegagna, K Hockemeyer, I Dolgalev, J Poźniak, F Rambow, Y Li, ... Nature communications 11 (1), 99, 2020 | 24 | 2020 |
SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response S Ibáñez-Molero, A van Vliet, J Pozniak, K Hummelink, AM Terry, ... Oncoimmunology 11 (1), 2139074, 2022 | 20 | 2022 |
An adverse tumor-protective effect of IDO1 inhibition JCN Kenski, X Huang, DW Vredevoogd, B de Bruijn, JJH Traets, ... Cell Reports Medicine 4 (2), 2023 | 16 | 2023 |
Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma LMN Melo, D Herrera-Rios, D Hinze, S Löffek, I Oezel, R Turiello, J Klein, ... Journal for Immunotherapy of Cancer 11 (4), e004150, 2023 | 15 | 2023 |
A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma J Pozniak, D Pedri, E Landeloos, YV Herck, A Antoranz, P Karras, ... bioRxiv, 2022.08. 11.502598, 2022 | 13 | 2022 |
MX 2 is a novel regulator of cell cycle in melanoma cells M Juraleviciute, J Pozniak, J Nsengimana, M Harland, J Randerson‐Moor, ... Pigment cell & melanoma research 33 (3), 446-457, 2020 | 13 | 2020 |
Tumor endothelial cell autophagy is a key vascular‐immune checkpoint in melanoma J Verhoeven, KA Jacobs, F Rizzollo, F Lodi, Y Hua, J Poźniak, ... EMBO Molecular Medicine 15 (12), e18028, 2023 | 12 | 2023 |
High-resolution copy number patterns from clinically relevant FFPE material A Filia, A Droop, M Harland, H Thygesen, J Randerson-Moor, H Snowden, ... Scientific Reports 9 (1), 8908, 2019 | 11 | 2019 |