Підписатись
Yury V. Popov
Yury V. Popov
Associate Professor of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School
Підтверджена електронна адреса в bidmc.harvard.edu - Домашня сторінка
Назва
Посилання
Посилання
Рік
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature 595 (7865), 107-113, 2021
7152021
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
A Omenetti, A Porrello, Y Jung, L Yang, Y Popov, SS Choi, RP Witek, ...
The Journal of clinical investigation 118 (10), 3331-3342, 2008
4462008
Targeting liver fibrosis: strategies for development and validation of antifibrotic therapies
Y Popov, D Schuppan
Hepatology 50 (4), 1294-1306, 2009
3872009
Mdr2 (Abcb4)-/-mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro-and antifibrogenic genes
Y Popov, E Patsenker, P Fickert, M Trauner, D Schuppan
Journal of hepatology 43 (6), 1045-1054, 2005
3142005
Vascular endothelial growth factor promotes fibrosis resolution and repair in mice
L Yang, J Kwon, Y Popov, GB Gajdos, T Ordog, RA Brekken, ...
Gastroenterology 146 (5), 1339-1350. e1, 2014
2952014
Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal
PYV Ikenaga N, Peng ZW, Vaid KA, Liu SB, Yoshida S, Sverdlov DY, Mikels ...
Gut, 2017
2862017
Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets
FM Fisher, PC Chui, IA Nasser, Y Popov, JC Cunniff, T Lundasen, ...
Gastroenterology 147 (5), 1073-1083. e6, 2014
2732014
Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis
P An, LL Wei, S Zhao, DY Sverdlov, KA Vaid, M Miyamoto, K Kuramitsu, ...
Nature communications 11 (1), 2362, 2020
2662020
Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease
GA Kwong, G Von Maltzahn, G Murugappan, O Abudayyeh, S Mo, ...
Nature biotechnology 31 (1), 63-70, 2013
2542013
Inhibition of integrin αvβ6 on cholangiocytes blocks transforming growth factor-β activation and retards biliary fibrosis progression
E Patsenker, Y Popov, F Stickel, A Jonczyk, SL Goodman, D Schuppan
Gastroenterology 135 (2), 660-670, 2008
2402008
Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice
SB Liu, N Ikenaga, ZW Peng, DY Sverdlov, A Greenstein, V Smith, ...
The FASEB Journal 30 (4), 1599-1609, 2016
2392016
Pharmacological inhibition of integrin αvβ3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis
E Patsenker, Y Popov, F Stickel, V Schneider, M Ledermann, H Sägesser, ...
Hepatology 50 (5), 1501-1511, 2009
2162009
Integrin αvβ6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies
Y Popov, E Patsenker, F Stickel, J Zaks, KR Bhaskar, G Niedobitek, ...
Journal of hepatology 48 (3), 453-464, 2008
2082008
Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells
A Schulze-Krebs, D Preimel, Y Popov, R Bartenschlager, V Lohmann, ...
Gastroenterology 129 (1), 246-258, 2005
2012005
Lysyl oxidase (LOX) family members: rationale and their potential as therapeutic targets for liver fibrosis
W Chen, A Yang, J Jia, YV Popov, D Schuppan, H You
Hepatology 72 (2), 729-741, 2020
2002020
Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice
Y Popov, DY Sverdlov, AK Sharma, KR Bhaskar, S Li, TL Freitag, J Lee, ...
Gastroenterology 140 (5), 1642-1652, 2011
1652011
Telomere dysfunction induces sirtuin repression that drives telomere-dependent disease
H Amano, A Chaudhury, C Rodriguez-Aguayo, L Lu, V Akhanov, A Catic, ...
Cell metabolism 29 (6), 1274-1290. e9, 2019
1632019
Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice
S Yoshida, N Ikenaga, SB Liu, ZW Peng, J Chung, DY Sverdlov, ...
Gastroenterology 147 (6), 1378-1392, 2014
1572014
Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis
Y Popov, DY Sverdlov, KR Bhaskar, AK Sharma, G Millonig, E Patsenker, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (3 …, 2010
1572010
The hedgehog pathway regulates remodelling responses to biliary obstruction in rats
A Omenetti, Y Popov, Y Jung, SS Choi, RP Witek, L Yang, KD Brown, ...
Gut 57 (9), 1275-1282, 2008
1532008
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