TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity BS Johnson, D Snead, JJ Lee, JM McCaffery, J Shorter, AD Gitler Journal of Biological Chemistry 284 (30), 20329-20339, 2009 | 903 | 2009 |
Alpha-synuclein function and dysfunction on cellular membranes D Snead, D Eliezer Experimental neurobiology 23 (4), 292, 2014 | 263 | 2014 |
Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction CK Deniston, J Salogiannis, S Mathea, DM Snead, I Lahiri, ... Nature 588 (7837), 344-349, 2020 | 205 | 2020 |
Motor mechanism for protein threading through Hsp104 P Wendler, J Shorter, D Snead, C Plisson, DK Clare, S Lindquist, ... Molecular cell 34 (1), 81-92, 2009 | 113 | 2009 |
Synaptic vesicles position complexin to block spontaneous fusion RT Wragg, D Snead, Y Dong, TF Ramlall, I Menon, J Bai, D Eliezer, ... Neuron 77 (2), 323-334, 2013 | 99 | 2013 |
Membrane curvature sensing by the C-terminal domain of complexin D Snead, RT Wragg, JS Dittman, D Eliezer Nature communications 5 (1), 4955, 2014 | 83 | 2014 |
Intrinsically disordered proteins in synaptic vesicle trafficking and release D Snead, D Eliezer Journal of Biological Chemistry 294 (10), 3325-3342, 2019 | 73 | 2019 |
Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation ME DeSantis, EA Sweeny, D Snead, EH Leung, MS Go, K Gupta, ... Journal of Biological Chemistry 289 (2), 848-867, 2014 | 55 | 2014 |
Probing structural transitions in the intrinsically disordered C-terminal domain of the measles virus nucleoprotein by vibrational spectroscopy of cyanylated cysteines CG Bischak, S Longhi, DM Snead, S Costanzo, E Terrer, CH Londergan Biophysical journal 99 (5), 1676-1683, 2010 | 52 | 2010 |
The accessory helix of complexin functions by stabilizing central helix secondary structure DT Radoff, Y Dong, D Snead, J Bai, D Eliezer, JS Dittman Elife 3, e04553, 2014 | 43 | 2014 |
Unique structural features of membrane-bound C-terminal domain motifs modulate complexin inhibitory function D Snead, AL Lai, RT Wragg, DA Parisotto, TF Ramlall, JS Dittman, ... Frontiers in molecular neuroscience 10, 154, 2017 | 35 | 2017 |
Evolutionary divergence of the c-terminal domain of complexin accounts for functional disparities between vertebrate and invertebrate complexins RT Wragg, DA Parisotto, Z Li, MS Terakawa, D Snead, I Basu, ... Frontiers in molecular neuroscience 10, 146, 2017 | 34 | 2017 |
Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules DM Snead, M Matyszewski, AM Dickey, YX Lin, AE Leschziner, ... Nature Structural & Molecular Biology 29 (12), 1196-1207, 2022 | 33 | 2022 |
Dynamic asymmetry and the role of the conserved active-site thiol in rabbit muscle creatine kinase CH Londergan, R Baskin, CG Bischak, KW Hoffman, DM Snead, ... Biochemistry 54 (1), 83-95, 2015 | 18 | 2015 |
Parkinson’s Disease-linked LRRK2 structure and model for microtubule interaction C Deniston University of California, San Diego, 2020 | 12 | 2020 |
The role of membrane affinity and binding modes in alpha-synuclein regulation of vesicle release and trafficking T Das, M Ramezani, D Snead, C Follmer, P Chung, KY Lee, DA Holowka, ... Biomolecules 12 (12), 1816, 2022 | 7 | 2022 |
Spectroscopic characterization of structure–function relationships in the intrinsically disordered protein complexin D Snead, D Eliezer Methods in enzymology 611, 227-286, 2018 | 4 | 2018 |
Erratum: TDP-43 intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity (Journal of Biological … BS Johnson, D Snead, JJ Lee, JM McCaffery, J Shorter, AD Gitler Journal of Biological Chemistry 284 (37), 25459, 2009 | 1 | 2009 |
LRRK2 cloning, plasmid construction, and mutagenesis D Snead, YX Lin | | 2023 |
Preparation of LRRK2 RCKW cryo-EM grids M Matyszewski, D Snead | | 2022 |