Primaquine revisited six decades after its discovery N Vale, R Moreira, P Gomes European journal of medicinal chemistry 44 (3), 937-953, 2009 | 434 | 2009 |
Praziquantel for schistosomiasis: single-drug metabolism revisited, mode of action, and resistance N Vale, MJ Gouveia, G Rinaldi, PJ Brindley, F Gärtner, ... Antimicrobial agents and chemotherapy 61 (5), 10.1128/aac. 02582-16, 2017 | 396 | 2017 |
Phenolic profiling of Portuguese propolis by LC–MS spectrometry: Uncommon propolis rich in flavonoid glycosides SI Falcão, N Vale, P Gomes, MRM Domingues, C Freire, SM Cardoso, ... Phytochemical Analysis 24 (4), 309-318, 2013 | 279 | 2013 |
Combination of cell-penetrating peptides with nanoparticles for therapeutic application: a review S Silva, AJ Almeida, N Vale Biomolecules 9 (1), 22, 2019 | 233 | 2019 |
Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity AS Correia, A Cardoso, N Vale Antioxidants 12 (2), 470, 2023 | 174 | 2023 |
Tryptophan metabolism in depression: A narrative review with a focus on serotonin and kynurenine pathways AS Correia, N Vale International journal of molecular sciences 23 (15), 8493, 2022 | 170 | 2022 |
“Recycling” classical drugs for malaria C Teixeira, N Vale, B Perez, A Gomes, JRB Gomes, P Gomes Chemical reviews 114 (22), 11164-11220, 2014 | 164 | 2014 |
Evaluation of synergism in drug combinations and reference models for future orientations in oncology D Duarte, N Vale Current Research in Pharmacology and Drug Discovery 3, 100110, 2022 | 154 | 2022 |
Antimicrobial peptides: a new class of antimalarial drugs? N Vale, L Aguiar, P Gomes Frontiers in Pharmacology 5, 275, 2014 | 117 | 2014 |
Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials MJ Araújo, J Bom, R Capela, C Casimiro, P Chambel, P Gomes, J Iley, ... Journal of medicinal chemistry 48 (3), 888-892, 2005 | 106 | 2005 |
In vitro evaluation of Portuguese propolis and floral sources for antiprotozoal, antibacterial and antifungal activity SI Falcão, N Vale, P Cos, P Gomes, C Freire, L Maes, M Vilas‐Boas Phytotherapy research 28 (3), 437-443, 2014 | 104 | 2014 |
Phenolic quantification and botanical origin of Portuguese propolis SI Falcão, A Tomás, N Vale, P Gomes, C Freire, M Vilas-Boas Industrial Crops and Products 49, 805-812, 2013 | 104 | 2013 |
Amino acids in the development of prodrugs N Vale, A Ferreira, J Matos, P Fresco, MJ Gouveia Molecules 23 (9), 2318, 2018 | 95 | 2018 |
Drug combination and repurposing for cancer therapy: The example of breast cancer AS Correia, F Gärtner, N Vale Heliyon 7 (1), 2021 | 90 | 2021 |
Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model MJ Gouveia, MY Pakharukova, T Laha, B Sripa, GA Maksimova, G Rinaldi, ... Carcinogenesis 38 (9), 929-937, 2017 | 86 | 2017 |
Cyclization-activated prodrugs P Gomes, N Vale, R Moreira Molecules 12 (11), 2484-2506, 2007 | 83 | 2007 |
Synthesis of imidazolidin-4-one and 1H-imidazo [2, 1-a] isoindole-2, 5 (3H, 9bH)-dione derivatives of primaquine: scope and limitations P Gomes, MJ Araújo, M Rodrigues, N Vale, Z Azevedo, J Iley, P Chambel, ... Tetrahedron 60 (26), 5551-5562, 2004 | 83 | 2004 |
Snake venom peptides and low mass proteins: molecular tools and therapeutic agents JR Almeida, LM Resende, RK Watanabe, VC Carregari, ... Current medicinal chemistry 24 (30), 3254-3282, 2017 | 78 | 2017 |
Advancing precision medicine: a review of innovative in silico approaches for drug development, clinical pharmacology and personalized healthcare L Marques, B Costa, M Pereira, A Silva, J Santos, L Saldanha, I Silva, ... Pharmaceutics 16 (3), 332, 2024 | 76 | 2024 |
Understanding breast cancer: From conventional therapies to repurposed drugs B Costa, I Amorim, F Gärtner, N Vale European Journal of Pharmaceutical Sciences 151, 105401, 2020 | 75 | 2020 |