The Keap1-Nrf2 system prevents onset of diabetes mellitus A Uruno, Y Furusawa, Y Yagishita, T Fukutomi, H Muramatsu, T Negishi, ... Molecular and cellular biology 33 (15), 2996-3010, 2013 | 374 | 2013 |
Broccoli or sulforaphane: is it the source or dose that matters? Y Yagishita, JW Fahey, AT Dinkova-Kostova, TW Kensler Molecules 24 (19), 3593, 2019 | 312 | 2019 |
The Keap1–Nrf2 system and diabetes mellitus A Uruno, Y Yagishita, M Yamamoto Archives of biochemistry and biophysics 566, 76-84, 2015 | 246 | 2015 |
Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice Y Yagishita, T Fukutomi, A Sugawara, H Kawamura, T Takahashi, J Pi, ... Diabetes 63 (2), 605-618, 2014 | 229 | 2014 |
Nrf2-mediated regulation of skeletal muscle glycogen metabolism A Uruno, Y Yagishita, F Katsuoka, Y Kitajima, A Nunomiya, R Nagatomi, ... Molecular and Cellular Biology 36 (11), 1655-1672, 2016 | 124 | 2016 |
Nrf2 improves leptin and insulin resistance provoked by hypothalamic oxidative stress Y Yagishita, A Uruno, T Fukutomi, R Saito, D Saigusa, J Pi, A Fukamizu, ... Cell Reports 18 (8), 2030-2044, 2017 | 123 | 2017 |
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms DL Palliyaguru, DV Chartoumpekis, N Wakabayashi, JJ Skoko, ... Free Radical Biology and Medicine 101, 116-128, 2016 | 95 | 2016 |
Current landscape of NRF2 biomarkers in clinical trials Y Yagishita, TN Gatbonton-Schwager, ML McCallum, TW Kensler Antioxidants 9 (8), 716, 2020 | 80 | 2020 |
Lymphatic mapping of mice with systemic lymphoproliferative disorder: usefulness as an inter-lymph node metastasis model of cancer L Shao, S Mori, Y Yagishita, T Okuno, Y Hatakeyama, T Sato, T Kodama Journal of immunological methods 389 (1-2), 69-78, 2013 | 73 | 2013 |
Nrf2 induces fibroblast growth factor 21 in diabetic mice Y Furusawa, A Uruno, Y Yagishita, C Higashi, M Yamamoto Genes to cells 19 (12), 864-878, 2014 | 71 | 2014 |
Transcription factor NF‐E2‐related factor 1 impairs glucose metabolism in mice Y Hirotsu, C Higashi, T Fukutomi, F Katsuoka, T Tsujita, Y Yagishita, ... Genes to Cells 19 (8), 650-665, 2014 | 59 | 2014 |
Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice DV Chartoumpekis, DL Palliyaguru, N Wakabayashi, M Fazzari, ... American Journal of Physiology-Endocrinology and Metabolism 315 (2), E180-E195, 2018 | 53 | 2018 |
Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice Y Yagishita, A Uruno, DV Chartoumpekis, TW Kensler, M Yamamoto Journal of Endocrinology 240 (3), 403-416, 2019 | 50 | 2019 |
The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice C Higashi, A Kawaji, N Tsuda, M Hayashi, R Saito, Y Yagishita, T Suzuki, ... European Journal of Pharmacology 802, 76-84, 2017 | 43 | 2017 |
Volumetric and angiogenic evaluation of antitumor effects with acoustic liposome and high-frequency ultrasound T Kodama, N Tomita, Y Yagishita, S Horie, K Funamoto, T Hayase, ... Cancer research 71 (22), 6957-6964, 2011 | 41 | 2011 |
Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice DV Chartoumpekis, Y Yagishita, M Fazzari, DL Palliyaguru, UNM Rao, ... JCI insight 3 (5), e97735, 2018 | 36 | 2018 |
Constitutive activation of Nrf2 in mice expands enterogenesis in small intestine through negative regulation of Math1 Y Yagishita, ML McCallum, TW Kensler, N Wakabayashi Cellular and Molecular Gastroenterology and Hepatology 11 (2), 503-524, 2021 | 18 | 2021 |
NRF2 and the Moirai: Life and death decisions on cell fates Y Yagishita, DV Chartoumpekis, TW Kensler, N Wakabayashi Antioxidants & redox signaling 38 (7-9), 684-708, 2023 | 12 | 2023 |
NRF2-mediated gene regulation and glucose homeostasis Y Yagishita, A Uruno, M Yamamoto Molecular nutrition and diabetes, 331-348, 2016 | 12 | 2016 |
A point mutation at C151 of Keap1 of mice abrogates NRF2 signaling, cytoprotection in vitro, and hepatoprotection in vivo by bardoxolone methyl (CDDO-Me) T Gatbonton-Schwager, Y Yagishita, T Joshi, N Wakabayashi, ... Molecular pharmacology 104 (2), 51-61, 2023 | 8 | 2023 |