Heme oxygenase–1 and carbon monoxide suppress autoimmune neuroinflammation ÂA Chora, P Fontoura, A Cunha, TF Pais, S Cardoso, PP Ho, LY Lee, ... The Journal of clinical investigation 117 (2), 438-447, 2007 | 379 | 2007 |
Polyphenols journey through blood-brain barrier towards neuronal protection I Figueira, G Garcia, RC Pimpão, AP Terrasso, I Costa, AF Almeida, ... Scientific reports 7 (1), 11456, 2017 | 287 | 2017 |
The NAD‐dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation TF Pais, ÉM Szegő, O Marques, L Miller‐Fleming, P Antas, P Guerreiro, ... The EMBO journal 32 (19), 2603-2616, 2013 | 195 | 2013 |
The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease RM De Oliveira, H Vicente Miranda, L Francelle, R Pinho, ÉM Szegö, ... PLoS biology 15 (3), e2000374, 2017 | 186 | 2017 |
Improved clearance of Mycobacterium avium upon disruption of the inducible nitric oxide synthase gene MS Gomes, M Flórido, TF Pais, R Appelberg The Journal of Immunology 162 (11), 6734-6739, 1999 | 161 | 1999 |
Microglia and inflammation: conspiracy, controversy or control? A Fernandes, L Miller-Fleming, TF Pais Cellular and Molecular Life Sciences 71, 3969-3985, 2014 | 148 | 2014 |
Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway TF Pais, C Figueiredo, R Peixoto, MH Braz, S Chatterjee Journal of neuroinflammation 5, 1-12, 2008 | 141 | 2008 |
SIRT2-and NRF2-targeting thiazole-containing compound with therapeutic activity in Huntington's disease models L Quinti, M Casale, S Moniot, TF Pais, MJ Van Kanegan, LS Kaltenbach, ... Cell chemical biology 23 (7), 849-861, 2016 | 94 | 2016 |
Macrophage control of mycobacterial growth induced by picolinic acid is dependent on host cell apoptosis TF Pais, R Appelberg The Journal of Immunology 164 (1), 389-397, 2000 | 88 | 2000 |
Brain macrophage activation in murine cerebral malaria precedes accumulation of leukocytes and CD8+ T cell proliferation TF Pais, S Chatterjee Journal of neuroimmunology 163 (1-2), 73-83, 2005 | 71 | 2005 |
Blocking the receptor for IL-10 improves antimycobacterial chemotherapy and vaccination RA Silva, TF Pais, R Appelberg The Journal of Immunology 167 (3), 1535-1541, 2001 | 71 | 2001 |
Sirtuins: common targets in aging and in neurodegeneration R Machado de Oliveira, T F Pais, T Fleming Outeiro Current drug targets 11 (10), 1270-1280, 2010 | 66 | 2010 |
Evaluation of IL-12 in immunotherapy and vaccine design in experimental Mycobacterium avium infections RA Silva, TF Pais, R Appelberg The Journal of Immunology 161 (10), 5578-5585, 1998 | 64 | 1998 |
Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase L Miller-Fleming, P Antas, TF Pais, JL Smalley, F Giorgini, TF Outeiro Proceedings of the National Academy of Sciences 111 (19), 7012-7017, 2014 | 63 | 2014 |
Analysis of T cells recruited during delayed‐type hypersensitivity to purified protein derivative (PPD) versus challenge with tuberculosis infection SILVA, SMEDEGAARD, APPELBERG, ANDERSEN Immunology 95 (1), 69-75, 1998 | 60 | 1998 |
Brain endothelium: the “innate immunity response hypothesis” in cerebral malaria pathogenesis TF Pais, C Penha-Gonçalves Frontiers in immunology 9, 3100, 2019 | 52 | 2019 |
Neuron‐microglia crosstalk up‐regulates neuronal FGF‐2 expression which mediates neuroprotection against excitotoxicity via JNK1/2 C Figueiredo, TF Pais, JR Gomes, S Chatterjee Journal of neurochemistry 107 (1), 73-85, 2008 | 47 | 2008 |
Antigen Specificity of T-Cell Response to Mycobacterium avium Infection in Mice TF Pais, JF Cunha, R Appelberg Infection and immunity 68 (8), 4805-4810, 2000 | 28 | 2000 |
Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control F Cardoso, F Castro, L Moreira-Teixeira, J Sousa, E Torrado, R Silvestre, ... PLoS One 10 (7), e0131904, 2015 | 27 | 2015 |
Mutant A53T α-synuclein improves rotarod performance before motor deficits and affects metabolic pathways PS Guerreiro, JE Coelho, I Sousa-Lima, P Macedo, LV Lopes, TF Outeiro, ... Neuromolecular medicine 19, 113-121, 2017 | 26 | 2017 |