Підписатись
Chris Denning
Chris Denning
Professor of Stem Cell Biology, University of Nottingham
Підтверджена електронна адреса в nottingham.ac.uk
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Nature biotechnology 29 (12), 1132-1144, 2011
6292011
Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
E Matsa, D Rajamohan, E Dick, L Young, I Mellor, A Staniforth, C Denning
European heart journal 32 (8), 952-962, 2011
4812011
Small molecule absorption by PDMS in the context of drug response bioassays
BJ Van Meer, H de Vries, KSA Firth, J van Weerd, LGJ Tertoolen, ...
Biochemical and biophysical research communications 482 (2), 323-328, 2017
4562017
Deletion of the α (1, 3) galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep
C Denning, S Burl, A Ainslie, J Bracken, A Dinnyes, J Fletcher, T King, ...
Nature biotechnology 19 (6), 559-562, 2001
3862001
Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability
PW Burridge, D Anderson, H Priddle, MD Barbadillo Muñoz, ...
Stem cells 25 (4), 929-938, 2007
3782007
Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform
C Denning, V Borgdorff, J Crutchley, KSA Firth, V George, S Kalra, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1728-1748, 2016
3532016
MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo
L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ...
Circulation research 122 (3), e5-e16, 2018
3462018
Transgenic enrichment of cardiomyocytes from human embryonic stem cells
D Anderson, T Self, IR Mellor, G Goh, SJ Hill, C Denning
Molecular Therapy 15 (11), 2027-2036, 2007
2772007
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for …
D Mosqueira, I Mannhardt, JR Bhagwan, K Lis-Slimak, P Katili, E Scott, ...
European heart journal 39 (43), 3879-3892, 2018
2542018
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
A Abakir, TC Giles, A Cristini, JM Foster, N Dai, M Starczak, ...
Nature genetics 52 (1), 48-55, 2020
2022020
Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome
C Allegrucci, YZ Wu, A Thurston, CN Denning, H Priddle, CL Mummery, ...
Human molecular genetics 16 (10), 1253-1268, 2007
2022007
Automated, scalable culture of human embryonic stem cells in feeder‐free conditions
RJ Thomas, D Anderson, A Chandra, NM Smith, LE Young, D Williams, ...
Biotechnology and Bioengineering 102 (6), 1636-1644, 2009
1822009
Materials for stem cell factories of the future
AD Celiz, JGW Smith, R Langer, DG Anderson, DA Winkler, DA Barrett, ...
Nature materials 13 (6), 570-579, 2014
1812014
Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease
C Hall, K Gehmlich, C Denning, D Pavlovic
Journal of the American Heart Association 10 (5), e019338, 2021
1692021
Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes
E Matsa, JE Dixon, C Medway, O Georgiou, MJ Patel, K Morgan, PJ Kemp, ...
European heart journal 35 (16), 1078-1087, 2014
1552014
Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will …
C Denning, JD Pitts
Human gene therapy 8 (15), 1825-1835, 1997
1371997
Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy
B Lin, Y Li, L Han, AD Kaplan, Y Ao, S Kalra, GCL Bett, RL Rasmusson, ...
Disease models & mechanisms 8 (5), 457-466, 2015
1352015
Current status of drug screening and disease modelling in human pluripotent stem cells
D Rajamohan, E Matsa, S Kalra, J Crutchley, A Patel, V George, ...
Bioessays 35 (3), 281-298, 2013
1312013
Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy
C Jiang, Y Wen, K Kuroda, K Hannon, MA Rudnicki, S Kuang
Disease models & mechanisms 7 (8), 997-1004, 2014
1302014
Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening
E Dick, D Rajamohan, J Ronksley, C Denning
Biochemical Society Transactions 38 (4), 1037-1045, 2010
1282010
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