Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer T Yamada, M Goto, V Punj, O Zaborina, ML Chen, K Kimbara, ... Proceedings of the National Academy of Sciences 99 (22), 14098-14103, 2002 | 255 | 2002 |
Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer V Punj, S Bhattacharyya, D Saint-Dic, C Vasu, EA Cunningham, J Graves, ... Oncogene 23 (13), 2367-2378, 2004 | 222 | 2004 |
Noncationic peptides obtained from azurin preferentially enter cancer cells BN Taylor, RR Mehta, T Yamada, F Lekmine, K Christov, AM Chakrabarty, ... Cancer research 69 (2), 537-546, 2009 | 214 | 2009 |
A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours MA Warso, JM Richards, D Mehta, K Christov, C Schaeffer, ... British journal of cancer 108 (5), 1061-1070, 2013 | 198 | 2013 |
Internalization of bacterial redox protein azurin in mammalian cells: entry domain and specificity T Yamada, AM Fialho, V Punj, L Bratescu, TKD Gupta, AM Chakrabarty Cellular microbiology 7 (10), 1418-1431, 2005 | 152 | 2005 |
Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin T Yamada, Y Hiraoka, M Ikehata, K Kimbara, BS Avner, TK Das Gupta, ... Proceedings of the National Academy of Sciences 101 (14), 4770-4775, 2004 | 151 | 2004 |
A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt RR Mehta, T Yamada, BN Taylor, K Christov, ML King, D Majumdar, ... Angiogenesis 14, 355-369, 2011 | 146 | 2011 |
Phase I trial of p28 (NSC745104), a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in pediatric patients with recurrent or progressive central nervous system tumors … RR Lulla, S Goldman, T Yamada, CW Beattie, L Bressler, M Pacini, ... Neuro-oncology 18 (9), 1319-1325, 2016 | 141 | 2016 |
The bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53 T Yamada, M Goto, V Punj, O Zaborina, K Kimbara, TK Das Gupta, ... Infection and immunity 70 (12), 7054-7062, 2002 | 139 | 2002 |
A peptide fragment of azurin induces a p53-mediated cell cycle arrest in human breast cancer cells T Yamada, RR Mehta, F Lekmine, K Christov, ML King, D Majumdar, ... Molecular cancer therapeutics 8 (10), 2947-2958, 2009 | 134 | 2009 |
p28, a first in class peptide inhibitor of cop1 binding to p53 T Yamada, K Christov, A Shilkaitis, L Bratescu, A Green, S Santini, ... British journal of cancer 108 (12), 2495-2504, 2013 | 108 | 2013 |
Cupredoxin− cancer interrelationship: Azurin binding with EphB2, interference in EphB2 tyrosine phosphorylation, and inhibition of cancer growth A Chaudhari, M Mahfouz, AM Fialho, T Yamada, AT Granja, Y Zhu, ... Biochemistry 46 (7), 1799-1810, 2007 | 108 | 2007 |
Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: tumour‐suppressor protein p53 and reactive oxygen species, but not redox activity, as … M Goto, T Yamada, K Kimbara, J Horner, M Newcomb, TKD Gupta, ... Molecular microbiology 47 (2), 549-559, 2003 | 103 | 2003 |
p28-Mediated Activation of p53 in G2–M Phase of the Cell Cycle Enhances the Efficacy of DNA Damaging and Antimitotic Chemotherapy T Yamada, TK Das Gupta, CW Beattie Cancer research 76 (8), 2354-2365, 2016 | 83 | 2016 |
p28, an anionic cell-penetrating peptide, increases the activity of wild type and mutated p53 without altering its conformation T Yamada, TK Das Gupta, CW Beattie Molecular pharmaceutics 10 (9), 3375-3383, 2013 | 68 | 2013 |
Azurin, Plasmodium falciparum Malaria and HIV/AIDS: Inhibition of Parasitic and Viral Growth by Azurin A Chaudhari, AM Fialho, D Ratner, P Gupta, CS Hong, S Kahali, ... Cell Cycle 5 (15), 1642-1648, 2006 | 65 | 2006 |
Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy AR Bizzarri, S Santini, E Coppari, M Bucciantini, S Di Agostino, T Yamada, ... International Journal of Nanomedicine, 3011-3019, 2011 | 59 | 2011 |
Disrupting the Entry Barrier and Attacking Brain Tumors: The Role of the Neisseria Lipobox-Containing H.8 Epitope and the Laz Protein CS Hong, T Yamada, AM Fialho, TKD Gupta, AM Chakrabarty Cell Cycle 5 (15), 1633-1641, 2006 | 53 | 2006 |
Cupredoxin derived transport agents and methods of use thereof A Chakrabarty, TD Gupta, T Yamada, A Fialho US Patent 7,691,383, 2010 | 51 | 2010 |
Peptide-based agents for cancer treatment: current applications and future directions NTT Nhàn, T Yamada, KH Yamada International Journal of Molecular Sciences 24 (16), 12931, 2023 | 50 | 2023 |