Multi-omic profiling of the developing human cerebral cortex at the single-cell level K Zhu, J Bendl, S Rahman, JM Vicari, C Coleman, T Clarence, ... Science advances 9 (41), eadg3754, 2023 | 67 | 2023 |
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease J Bendl, ME Hauberg, K Girdhar, E Im, JM Vicari, S Rahman, ... Nature neuroscience 25 (10), 1366-1378, 2022 | 47 | 2022 |
Population-level variation in enhancer expression identifies disease mechanisms in the human brain P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, ... Nature genetics 54 (10), 1493-1503, 2022 | 33 | 2022 |
IL10RB as a key regulator of COVID-19 host susceptibility and severity G Voloudakis, G Hoffman, S Venkatesh, KM Lee, K Dobrindt, JM Vicari, ... medRxiv, 2021 | 16 | 2021 |
A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility G Voloudakis, JM Vicari, S Venkatesh, GE Hoffman, K Dobrindt, W Zhang, ... NPJ Genomic Medicine 7 (1), 52, 2022 | 8 | 2022 |
Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease D Lee, JM Vicari, C Porras, C Spencer, M Pjanic, X Wang, S Kinrot, ... medRxiv, 2023.10. 25.23297558, 2023 | 5 | 2023 |
Multi-omic atlas of the parahippocampal gyrus in Alzheimer’s disease C Coleman, M Wang, E Wang, C Micallef, Z Shao, JM Vicari, Y Li, K Yu, ... Scientific Data 10 (1), 602, 2023 | 5 | 2023 |
Exosome-based therapy for ischemic stroke: A bibliometric analysis of current trends and future directions BR Schuldt, R Kalagara, S Chennareddy, IC Odland, MH Downes, ... World Neurosurgery 171, e195-e205, 2023 | 5 | 2023 |
Population-level variation of enhancer expression identifies novel disease mechanisms in the human brain P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, ... | 4 | 2021 |
Alzheimer’s disease transcriptional landscape in ex-vivo human microglia P Roussos, R Kosoy, J Fullard, J Bendl, S Kleopoulos, Z Shao, S Argyriou, ... Research Square, rs. 3. rs-3851590, 2024 | 2 | 2024 |
Diets, genes, and drugs that increase lifespan and delay age-related diseases: Role of nutrient-sensing neurons and Creb-binding protein R Litke, J Vicari, BT Huang, D Gonzalez, N Grimaldi, O Sharma, G Ma, ... Pharmacology Biochemistry and Behavior 219, 173428, 2022 | 2 | 2022 |
Transcribed enhancers in the human brain identify novel disease risk mechanisms P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, ... BioRxiv, 2021.05. 14.443421, 2021 | 2 | 2021 |
Abstract TP211: In silico drug repurposing identifies transcriptional mitigators of blood-induced neurotoxicity in an organoid model of intracerebral hemorrhage C Seah, B Schuldt, J Vicari, C Lebakken, W Richards, K Greuel, K Parham, ... Stroke 56 (Suppl_1), ATP211-ATP211, 2025 | | 2025 |
Abstract TMP75: Reduced thrombus immunoreactivity is transcriptionally associated with greater NIHSS severity at presentation of ischemic stroke: Analysis from the INSIGHT registry C Seah, A Devarajan, J Vicari, A Dabney, S Baltan, F Sohrabji, ... Stroke 56 (Suppl_1), ATMP75-ATMP75, 2025 | | 2025 |
A distinct clot transcriptomic signature is associated with atrial fibrillation-derived ischemic stroke in the INSIGHT Registry C Seah, A Devarajan, J Vicari, A Dabney, S Baltan, F Sohrabji, ... Stroke 56 (Suppl_1), A14-A14, 2025 | | 2025 |
A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19 G Voloudakis, KM Lee, JM Vicari, W Zhang, D Hoagland, S Venkatesh, ... medRxiv, 2025.01. 10.25320348, 2025 | | 2025 |
Temporal Blood Exposure in Neural Organoids Stimulates Dynamic Astrocyte Reactivity C Seah, BR Schuldt, J Vicari, C Lebakken, CP Kellner Stroke 55 (Suppl_1), A56-A56, 2024 | | 2024 |
Phenothiazine compounds for the treatment of alzheimer's disease and other age-related and neurological diseases C Mobbs, J Jin, C Kellner, HU Kaniskan, T Cao, J Hu, J Vicari, BT Huang, ... US Patent App. 18/036,095, 2024 | | 2024 |
Novel small molecules inhibit proteotoxicity and inflammation: Mechanistic and therapeutic implications for Alzheimer’s Disease, healthspan and lifespan-Aging as a consequence … R Litke, J Vicari, BT Huang, L Shapiro, KH Roh, A Silver, P Talreja, ... bioRxiv, 2023 | | 2023 |
Abstract TMP81: Immunocompetent Neural Organoids Respond To Blood Stimulation: A Novel Model Of Intracerebral Hemorrhage BR Schuldt, JM Vicari, CP Kellner Stroke 54 (Suppl_1), ATMP81-ATMP81, 2023 | | 2023 |