IgM autoantibodies recognizing ACE2 are associated with severe COVID-19 L Casciola-Rosen, DR Thiemann, F Andrade, MIT Zambrano, JE Hooper, ... MedRxiv, 2020 | 49 | 2020 |
IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function L Casciola-Rosen, DR Thiemann, F Andrade, MI Trejo-Zambrano, ... JCI insight 7 (9), e158362, 2022 | 48 | 2022 |
Engineered antibody fusion proteins for targeted disease therapy AB Silver, EK Leonard, JR Gould, JB Spangler Trends in pharmacological sciences 42 (12), 1064-1081, 2021 | 35 | 2021 |
Antibody–Invertase Fusion Protein Enables Quantitative Detection of SARS-CoV-2 Antibodies Using Widely Available Glucometers EK Leonard, M Aller Pellitero, B Juelg, JB Spangler, N Arroyo-Currás Journal of the American Chemical Society 144 (25), 11226-11237, 2022 | 20 | 2022 |
Nanoparticle-based modulation of CD4+ T cell effector and helper functions enhances adoptive immunotherapy A Isser, AB Silver, HC Pruitt, M Mass, EH Elias, G Aihara, SS Kang, ... Nature communications 13 (1), 6086, 2022 | 13 | 2022 |
Design and validation of a corneal bioreactor EK Leonard, VH Pai, P Amberg, J Gardner, EJ Orwin Biotechnology and bioengineering 109 (12), 3189-3198, 2012 | 13 | 2012 |
Supramolecular filaments for concurrent ACE2 docking and enzymatic activity silencing enable coronavirus capture and infection prevention CF Anderson, Q Wang, D Stern, EK Leonard, B Sun, KJ Fergie, C Choi, ... Matter 6 (2), 583-604, 2023 | 10 | 2023 |
Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity EK Leonard, J Tomala, JR Gould, MI Leff, JX Lin, P Li, MJ Porter, ... bioRxiv, 2023 | 8 | 2023 |
In Vivo Stimulation of Therapeutic Antigen‐Specific T Cells in an Artificial Lymph Node Matrix NK Livingston, JW Hickey, H Sim, SF Salathe, J Choy, J Kong, AB Silver, ... Advanced Materials 36 (23), 2310043, 2024 | 5 | 2024 |
Methods and materials for targeted expansion of immune effector cells J Spangler, J Tomala, MI Leff, S Ludwig, EK Leonard, M Kovár, ... US Patent App. 17/622,539, 2022 | 3 | 2022 |
Cytokine/antibody fusion protein design and evaluation CS Fabilane, AC Stephenson, EK Leonard, D VanDyke, JB Spangler Current Protocols 4 (5), e1061, 2024 | 2 | 2024 |
Weaponizing T-cell receptors through molecular engineering EK Leonard, MI Leff, JB Spangler Journal of Biological Chemistry 294 (15), 5805-5806, 2019 | 2 | 2019 |
In Vivo Stimulation of Therapeutic Antigen‐Specific T Cells in an Artificial Lymph Node Matrix (Adv. Mater. 23/2024) NK Livingston, JW Hickey, H Sim, SF Salathe, J Choy, J Kong, AB Silver, ... Advanced Materials 36 (23), 2470177, 2024 | | 2024 |
Methods and related aspects for pathogen detection N Arroyo, J Spangler, HA Taekjip, EK Leonard, MA Pellitero, SC Hur, ... US Patent App. 18/044,923, 2023 | | 2023 |
Structural Characterization of an Effector-Biasing IL-2 Immunocytokine J Gould, E Leonard, J Spangler 2022 AIChE Annual Meeting, 2022 | | 2022 |
Directed Evolution of PDGFR-β and PDGF-BB for Promotion of Bone Regeneration. M Kizerwetter, E Leonard, A Harmalkar, A Horenberg, M Leff, W Grayson, ... 2021 AIChE Annual Meeting, 2021 | | 2021 |
Engineered Immunocytokines Improve Delivery of IL-2 to Pro-Inflammatory Cells and Promote Anti-Tumor Activity. E Leonard 2021 AIChE Annual Meeting, 2021 | | 2021 |
Optimizing Bias for Activation of Tumor-Reactive T Cell Subsets E Leonard, J Spangler 2019 AIChE Annual Meeting, 2019 | | 2019 |
Characterization of the effect of visible electromagnetic signals on corneal fibroblasts EK Leonard, EJ Orwin JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 6, 140-140, 2012 | | 2012 |
Characterizing Strain of a Bioreactor for Rabbit Corneal Fibroblasts–Experimental Verification of Finite Element Models VH Pai, EK Leonard, EJ Orwin | | |