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Hadrien Demagny
Hadrien Demagny
Senior Scientist, Life Sciences Department, Ecole Polytechnique Fédérale de Lausanne (EPFL)
Підтверджена електронна адреса в epfl.ch - Домашня сторінка
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Molecular physiology of bile acid signaling in health, disease, and aging
A Perino*, H Demagny*, L Velazquez-Villegas, K Schoonjans
Physiological reviews 101 (2), 683-731, 2021
3302021
The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-β signaling
H Demagny, T Araki, EM De Robertis
Cell reports 9 (2), 688-700, 2014
872014
Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad
E Eivers, H Demagny, EM De Robertis
Cytokine & growth factor reviews 20 (5-6), 357-365, 2009
872009
LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer
P Xu, MH Oosterveer, S Stein, H Demagny, D Ryu, N Moullan, X Wang, ...
Genes & development 30 (11), 1255-1260, 2016
842016
Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease
S Stein, V Lemos, P Xu, H Demagny, X Wang, D Ryu, V Jimenez, F Bosch, ...
The Journal of clinical investigation 127 (2), 583-592, 2017
762017
Point mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGF-β signaling
H Demagny, EM De Robertis
Molecular & Cellular Oncology 3 (1), e1025181, 2016
432016
Emerging functions of the nuclear receptor LRH-1 in liver physiology and pathology
Y Sun*, H Demagny*, K Schoonjans
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (8), 166145, 2021
372021
Phosphorylation of Mad controls competition between wingless and BMP signaling
E Eivers*, H Demagny*, RH Choi, EM De Robertis
Science signaling 4 (194), ra68-ra68, 2011
362011
The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosis
N Bresciani, H Demagny, V Lemos, F Pontanari, X Li, Y Sun, H Li, ...
Journal of Hepatology 77 (4), 1071-1082, 2022
242022
Asparagine protects pericentral hepatocytes during acute liver injury
Y Sun*, H Demagny*, A Faure, F Pontanari, A Jalil, N Bresciani, E Yildiz, ...
The Journal of Clinical Investigation, 2023
212023
Smad4/DPC4: A barrier against tumor progression driven by RTK/Ras/Erk and Wnt/GSK3 signaling
H Demagny, EM De Robertis
Molecular & cellular oncology 3 (2), e989133, 2016
202016
A microbial-derived succinylated bile acid to safeguard liver health
A Perino*, H Demagny*, K Schoonjans
Cell 187 (11), 2687-2689, 2024
32024
Wars1 downregulation in hepatocytes induces mitochondrial stress and disrupts metabolic homeostasis
F Pontanari, H Demagny, A Faure, X Li, G Benegiamo, A Jalil, A Perino, ...
Metabolism 162, 156061, 2025
12025
Protecting liver health with microbial-derived succinylated bile acids
H Demagny, A Perino, K Schoonjans
Life Metabolism 3 (5), loae023, 2024
2024
Convergence of the wnt, fgf and tgf-beta signaling pathways at the levels of the transcription factors smad1 and smad4
H Demagny
Université Pierre et Marie Curie-Paris VI, 2014
2014
Convergence des voies de signalisation wnt, fgf et tgf-beta au niveau des facteurs de transcription smad1 et smad4.
H Demagny
Paris 6, 2014
2014
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