Підписатись
Nimansha Jain
Nimansha Jain
MD-PhD Student, Washington University School of Medicine
Підтверджена електронна адреса в wustl.edu
Назва
Посилання
Посилання
Рік
TREM2 function impedes tau seeding in neuritic plaques
CEG Leyns, M Gratuze, S Narasimhan, N Jain, LJ Koscal, H Jiang, ...
Nature neuroscience 22 (8), 1217-1222, 2019
2692019
ApoE isoform–and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy
D Seo, D O’Donnell, N Jain, JD Ulrich, J Herz, Y Li, M Lemieux, J Cheng, ...
Science 379 (6628), eadd1236, 2023
1602023
Activated microglia mitigate Aβ-associated tau seeding and spreading
M Gratuze, Y Chen, S Parhizkar, N Jain, MR Strickland, JR Serrano, ...
Journal of Experimental Medicine 218 (8), e20210542, 2021
1512021
GPNMB confers risk for Parkinson’s disease through interaction with α-synuclein
ME Diaz-Ortiz, Y Seo, M Posavi, M Carceles Cordon, E Clark, N Jain, ...
Science 377 (6608), eabk0637, 2022
1022022
Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading
N Jain, CA Lewis, JD Ulrich, DM Holtzman
Journal of Experimental Medicine 220 (1), 2023
922023
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
Nature immunology 24 (11), 1839-1853, 2023
852023
Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes
JI Busch, TL Unger, N Jain, R Tyler Skrinak, RA Charan, AS Chen-Plotkin
Human molecular genetics 25 (13), 2681-2697, 2016
732016
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
M Gratuze, JCM Schlachetzki, RDO Albanus, N Jain, B Novotny, L Brase, ...
Neuron 111 (2), 202-219. e7, 2023
592023
Common variant rs356182 near SNCA defines a Parkinson's disease endophenotype
CA Cooper, N Jain, MD Gallagher, D Weintraub, SX Xie, Y Berlyand, ...
Annals of clinical and translational neurology 4 (1), 15-25, 2017
412017
Genetic modifiers in neurodegeneration
N Jain, AS Chen-Plotkin
Current genetic medicine reports 6, 11-19, 2018
242018
Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions
A Ray, P Katoch, N Jain, PP Mehta
Journal of cell science 131 (5), jcs207340, 2018
152018
TREM2 and microglia exosomes: a potential highway for pathological tau
N Jain, JD Ulrich
Molecular neurodegeneration 17 (1), 73, 2022
112022
Insights from new in vivo models of TREM2 variants
N Jain, DM Holtzman
Molecular neurodegeneration 18 (1), 21, 2023
32023
Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy
W Brandao, N Jain, Z Yin, KL Kleemann, M Carpenter, X Bao, JR Serrano, ...
Science Translational Medicine 17 (781), eadk3690, 2025
2025
Degeneration
N Jain
2024
APOE4 impairs Microglia‐Astrocyte Crosstalk in Alzheimer Disease
K Kleemann, N Rosenzweig, Z Yin, X Zhang, WN Brandao, M Margeta, ...
Alzheimer's & Dementia 19, e071852, 2023
2023
APOE4 impairs microglia‐astrocyte response in Alzheimer’s disease by inducing TGFβ‐mediated checkpoints
O Butovsky, Z Yin, N Rosenzweig, K Kleemann, X Zhang, WN Brandao, ...
Alzheimer's & Dementia 19, e076510, 2023
2023
Xenon gas (Xe) treatment to restore microglial functions in Alzheimer’s disease (AD)
WN Brandao, Z Yin, K Kleemann, X Zhang, N Rosenzweig, N Jain, ...
Alzheimer's & Dementia 19, e076467, 2023
2023
Testing for Allele-specific Expression from Human Brain Samples
ME Diaz-Ortiz, N Jain, MD Gallagher, M Posavi, TL Unger, ...
Bio-protocol 13 (19), e4832, 2023
2023
Suppressing ApoE ε4 allele protects against signs of Alzheimer’s disease
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
2023
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