T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection EF McKinney, JC Lee, DRW Jayne, PA Lyons, KGC Smith Nature 523 (7562), 612-616, 2015 | 716 | 2015 |
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 DA Collier, IATM Ferreira, P Kotagiri, RP Datir, EY Lim, E Touizer, B Meng, ... Nature 596 (7872), 417-422, 2021 | 707 | 2021 |
From big data to precision medicine T Hulsen, SS Jamuar, AR Moody, JH Karnes, O Varga, S Hedensted, ... Frontiers in medicine 6, 34, 2019 | 470 | 2019 |
A CD8+ T cell transcription signature predicts prognosis in autoimmune disease EF McKinney, PA Lyons, EJ Carr, JL Hollis, DRW Jayne, LC Willcocks, ... Nature medicine 16 (5), 586-591, 2010 | 422 | 2010 |
Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis JC Lee, PA Lyons, EF McKinney, JM Sowerby, EJ Carr, F Bredin, ... The Journal of clinical investigation 121 (10), 4170-4179, 2011 | 335 | 2011 |
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes RC Ferreira, H Guo, RMR Coulson, DJ Smyth, ML Pekalski, OS Burren, ... Diabetes 63 (7), 2538-2550, 2014 | 331 | 2014 |
Introducing the endotype concept to address the challenge of disease heterogeneity in type 1 diabetes M Battaglia, S Ahmed, MS Anderson, MA Atkinson, D Becker, PJ Bingley, ... Diabetes care 43 (1), 5-12, 2020 | 319 | 2020 |
The longitudinal dynamics and natural history of clonal haematopoiesis MA Fabre, JG de Almeida, E Fiorillo, E Mitchell, A Damaskou, J Rak, ... Nature 606 (7913), 335-342, 2022 | 276 | 2022 |
Analysis of the B cell receptor repertoire in six immune-mediated diseases RJM Bashford-Rogers, L Bergamaschi, EF McKinney, DC Pombal, ... Nature 574 (7776), 122-126, 2019 | 257 | 2019 |
How artificial intelligence and machine learning can help healthcare systems respond to COVID-19 M Van der Schaar, AM Alaa, A Floto, A Gimson, S Scholtes, A Wood, ... Machine Learning 110, 1-14, 2021 | 208 | 2021 |
A blood-based prognostic biomarker in IBD D Biasci, JC Lee, NM Noor, DR Pombal, M Hou, N Lewis, T Ahmad, ... Gut 68 (8), 1386-1395, 2019 | 189 | 2019 |
High prevalence of autoantibodies to hLAMP-2 in anti–neutrophil cytoplasmic antibody–associated vasculitis R Kain, H Tadema, EF McKinney, A Benharkou, R Brandes, A Peschel, ... Journal of the American Society of Nephrology 23 (3), 556-566, 2012 | 181 | 2012 |
Association between polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers EF McKinney, RT Walton, P Yudkin, A Fuller, NA Haldar, D Mant, ... Pharmacogenetics and Genomics 10 (6), 483-491, 2000 | 173 | 2000 |
Novel expression signatures identified by transcriptional analysis of separated leucocyte subsets in systemic lupus erythematosus and vasculitis PA Lyons, EF McKinney, TF Rayner, A Hatton, HB Woffendin, ... Annals of the rheumatic diseases 69 (6), 1208-1213, 2010 | 130 | 2010 |
Donor cytokine genotype influences the development of acute rejection after renal transplantation SE Marshall, AJ McLaren, EF McKinney, TG Bird, NA Haldar, M Bunce, ... Transplantation 71 (3), 469-476, 2001 | 127 | 2001 |
Metabolic exhaustion in infection, cancer and autoimmunity EF McKinney, KGC Smith Nature immunology 19 (3), 213-221, 2018 | 114 | 2018 |
A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open … NM Noor, JC Lee, S Bond, F Dowling, B Brezina, KV Patel, T Ahmad, ... The Lancet Gastroenterology & Hepatology 9 (5), 415-427, 2024 | 102 | 2024 |
The immunopathology of ANCA-associated vasculitis EF McKinney, LC Willcocks, V Broecker, KGC Smith Seminars in immunopathology 36, 461-478, 2014 | 102 | 2014 |
T cell exhaustion and immune-mediated disease—the potential for therapeutic exhaustion EF McKinney, KGC Smith Current opinion in immunology 43, 74-80, 2016 | 95 | 2016 |
Transcript analysis reveals a specific HOX signature associated with positional identity of human endothelial cells M Toshner, BJ Dunmore, EF McKinney, M Southwood, P Caruso, ... PloS one 9 (3), e91334, 2014 | 70 | 2014 |