| Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection NS Butler, J Moebius, LL Pewe, B Traore, OK Doumbo, LT Tygrett, ... Nature immunology 13 (2), 188-195, 2012 | 588 | 2012 |
| Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB S Sanlioglu, CM Williams, L Samavati, NS Butler, G Wang, PB McCray Jr, ... Journal of Biological Chemistry 276 (32), 30188-30198, 2001 | 505 | 2001 |
| Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin MM Monick, TO Yarovinsky, LS Powers, NS Butler, AB Carter, ... Journal of Biological Chemistry 278 (52), 53035-53044, 2003 | 385 | 2003 |
| Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion J Illingworth, NS Butler, S Roetynck, J Mwacharo, SK Pierce, P Bejon, ... The Journal of Immunology 190 (3), 1038-1047, 2013 | 341 | 2013 |
| Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria NW Schmidt, RL Podyminogin, NS Butler, VP Badovinac, BJ Tucker, ... Proceedings of the National Academy of Sciences 105 (37), 14017-14022, 2008 | 315 | 2008 |
| Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites NS Butler, NW Schmidt, AM Vaughan, AS Aly, SHI Kappe, JT Harty Cell host & microbe 9 (6), 451-462, 2011 | 293 | 2011 |
| Interleukin-10 directly inhibits CD8+ T cell function by enhancing N-glycan branching to decrease antigen sensitivity LK Smith, GM Boukhaled, SA Condotta, S Mazouz, JJ Guthmiller, R Vijay, ... Immunity 48 (2), 299-312. e5, 2018 | 270 | 2018 |
| T cell-mediated immunity to malaria SP Kurup, NS Butler, JT Harty Nature Reviews Immunology 19 (7), 457-471, 2019 | 253 | 2019 |
| Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites NW Schmidt, NS Butler, VP Badovinac, JT Harty PLoS pathogens 6 (7), e1000998, 2010 | 228 | 2010 |
| Role of repeated lung injury and genetic background in bleomycin-induced fibrosis MP Chung, MM Monick, NY Hamzeh, NS Butler, LS Powers, ... American journal of respiratory cell and molecular biology 29 (3), 375-380, 2003 | 177 | 2003 |
| Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4 SP Kurup, N Obeng-Adjei, SM Anthony, B Traore, OK Doumbo, NS Butler, ... Nature medicine 23 (10), 1220-1225, 2017 | 141 | 2017 |
| Anti-inflammatory response is associated with mortality and severity of infection in sepsis A Ashare, LS Powers, NS Butler, KC Doerschug, MM Monick, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (4 …, 2005 | 141 | 2005 |
| PD-1 co-inhibitory and OX40 co-stimulatory crosstalk regulates helper T cell differentiation and anti-Plasmodium humoral immunity RA Zander, N Obeng-Adjei, JJ Guthmiller, DI Kulu, J Li, A Ongoiba, ... Cell host & microbe 17 (5), 628-641, 2015 | 118 | 2015 |
| Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA MM Monick, PK Robeff, NS Butler, DM Flaherty, AB Carter, MW Peterson, ... Journal of Biological Chemistry 277 (36), 32992-33000, 2002 | 110 | 2002 |
| Differential effector pathways regulate memory CD8 T cell immunity against Plasmodium berghei versus P. yoelii sporozoites NS Butler, NW Schmidt, JT Harty The Journal of Immunology 184 (5), 2528-2538, 2010 | 106 | 2010 |
| Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria R Vijay, JJ Guthmiller, AJ Sturtz, FA Surette, KJ Rogers, RR Sompallae, ... Nature immunology 21 (7), 790-801, 2020 | 103 | 2020 |
| Cutting edge: IL-10 is essential for the generation of germinal center B cell responses and anti-plasmodium humoral immunity JJ Guthmiller, AC Graham, RA Zander, RL Pope, NS Butler The Journal of Immunology 198 (2), 617-622, 2017 | 97 | 2017 |
| Immunologic considerations for generating memory CD8 T cells through vaccination NS Butler, JC Nolz, JT Harty Cellular microbiology 13 (7), 925-933, 2011 | 96 | 2011 |
| Sphingosine kinase mediates activation of extracellular signal–related kinase and Akt by respiratory syncytial virus MM Monick, K Cameron, LS Powers, NS Butler, D McCoy, RK Mallampalli, ... American journal of respiratory cell and molecular biology 30 (6), 844-852, 2004 | 93 | 2004 |
| Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria J Rivera-Correa, JJ Guthmiller, R Vijay, C Fernandez-Arias, ... Nature communications 8 (1), 1282, 2017 | 92 | 2017 |