Virus genomes reveal factors that spread and sustained the Ebola epidemic G Dudas, LM Carvalho, T Bedford, AJ Tatem, G Baele, NR Faria, DJ Park, ... Nature 544 (7650), 309-315, 2017 | 467 | 2017 |
Evolution of enhanced innate immune evasion by the SARS-CoV-2 B. 1.1. 7 UK variant LG Thorne, M Bouhaddou, AK Reuschl, L Zuliani-Alvarez, B Polacco, ... bioRxiv, 2021 | 430* | 2021 |
Norovirus gene expression and replication LG Thorne, IG Goodfellow Journal of General Virology 95 (2), 278-291, 2014 | 362 | 2014 |
SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation LG Thorne, AK Reuschl, L Zuliani-Alvarez, MVX Whelan, M Noursadeghi, ... BioRxiv, 2020 | 216 | 2020 |
Experimental treatment of Ebola virus disease with TKM-130803: a single-arm phase 2 clinical trial J Dunning, F Sahr, A Rojek, F Gannon, G Carson, B Idriss, T Massaquoi, ... PLoS medicine 13 (4), e1001997, 2016 | 199 | 2016 |
Favipiravir elicits antiviral mutagenesis during virus replication in vivo A Arias, L Thorne, I Goodfellow Elife 3, e03679, 2014 | 190 | 2014 |
Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases A Arias, SJ Watson, D Asogun, EA Tobin, J Lu, MVT Phan, U Jah, ... Virus Evolution 2 (1), 2016 | 143 | 2016 |
Cyclosporine H overcomes innate immune restrictions to improve lentiviral transduction and gene editing in human hematopoietic stem cells C Petrillo, LG Thorne, G Unali, G Schiroli, AMS Giordano, F Piras, ... Cell Stem Cell 23 (6), 820-832. e9, 2018 | 113 | 2018 |
Murine norovirus: propagation, quantification, and genetic manipulation S Hwang, B Alhatlani, A Arias, SL Caddy, C Christodoulou, ... Current protocols in microbiology 33 (1), 15K. 2.1-15K. 2.61, 2014 | 103 | 2014 |
Interleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells JA Harker, A Godlee, JL Wahlsten, DCP Lee, LG Thorne, D Sawant, ... Journal of virology 84 (8), 4073-4082, 2010 | 75 | 2010 |
Noroviruses co-opt the function of host proteins VAPA and VAPB for replication via a phenylalanine–phenylalanine-acidic-tract-motif mimic in nonstructural viral protein NS1/2 BT McCune, W Tang, J Lu, JB Eaglesham, L Thorne, AE Mayer, E Condiff, ... MBio 8 (4), e00668-17, 2017 | 64 | 2017 |
High-resolution functional profiling of the norovirus genome L Thorne, D Bailey, I Goodfellow Journal of virology 86 (21), 11441-11456, 2012 | 55 | 2012 |
HIV-1 Vpr antagonizes cGAS sensing by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport H Khan, RP Sumner, J Rasaiyaah, CP Tan, MT Rodriguez-Plata, ... bioRxiv, 2020 | 48* | 2020 |
Are evolution and the intracellular innate immune system key determinants in HIV transmission? RP Sumner, LG Thorne, DL Fink, H Khan, RS Milne, GJ Towers Frontiers in immunology 8, 1246, 2017 | 42 | 2017 |
The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis MA Yunus, X Lin, D Bailey, I Karakasiliotis, Y Chaudhry, S Vashist, ... Journal of virology 89 (2), 1218-1229, 2015 | 41 | 2015 |
Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B. 1.1. 7 variant AK Reuschl, LG Thorne, L Zuliani-Alvarez, M Bouhaddou, K Obernier, ... bioRxiv, 2021 | 37 | 2021 |
Norovirus polymerase fidelity contributes to viral transmission in vivo A Arias, L Thorne, E Ghurburrun, D Bailey, I Goodfellow MSphere 1 (5), 2016 | 33 | 2016 |
Advances toward a norovirus antiviral: from classical inhibitors to lethal mutagenesis L Thorne, A Arias, I Goodfellow The Journal of infectious diseases 213 (suppl_1), S27-S31, 2016 | 33 | 2016 |
Reverse genetics mediated recovery of infectious murine norovirus A Arias, L Ureña, L Thorne, MA Yunus, I Goodfellow JoVE (Journal of Visualized Experiments), e4145, 2012 | 33 | 2012 |
Characterisation of B. 1.1. 7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2. SJ Dicken, MJ Murray, LG Thorne, AK Reuschl, C Forrest, ... bioRxiv, 2021 | 32 | 2021 |