Підписатись
Lucy Thorne
Lucy Thorne
Підтверджена електронна адреса в ucl.ac.uk
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Посилання
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Virus genomes reveal factors that spread and sustained the Ebola epidemic
G Dudas, LM Carvalho, T Bedford, AJ Tatem, G Baele, NR Faria, DJ Park, ...
Nature 544 (7650), 309-315, 2017
4672017
Evolution of enhanced innate immune evasion by the SARS-CoV-2 B. 1.1. 7 UK variant
LG Thorne, M Bouhaddou, AK Reuschl, L Zuliani-Alvarez, B Polacco, ...
bioRxiv, 2021
430*2021
Norovirus gene expression and replication
LG Thorne, IG Goodfellow
Journal of General Virology 95 (2), 278-291, 2014
3622014
SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation
LG Thorne, AK Reuschl, L Zuliani-Alvarez, MVX Whelan, M Noursadeghi, ...
BioRxiv, 2020
2162020
Experimental treatment of Ebola virus disease with TKM-130803: a single-arm phase 2 clinical trial
J Dunning, F Sahr, A Rojek, F Gannon, G Carson, B Idriss, T Massaquoi, ...
PLoS medicine 13 (4), e1001997, 2016
1992016
Favipiravir elicits antiviral mutagenesis during virus replication in vivo
A Arias, L Thorne, I Goodfellow
Elife 3, e03679, 2014
1902014
Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases
A Arias, SJ Watson, D Asogun, EA Tobin, J Lu, MVT Phan, U Jah, ...
Virus Evolution 2 (1), 2016
1432016
Cyclosporine H overcomes innate immune restrictions to improve lentiviral transduction and gene editing in human hematopoietic stem cells
C Petrillo, LG Thorne, G Unali, G Schiroli, AMS Giordano, F Piras, ...
Cell Stem Cell 23 (6), 820-832. e9, 2018
1132018
Murine norovirus: propagation, quantification, and genetic manipulation
S Hwang, B Alhatlani, A Arias, SL Caddy, C Christodoulou, ...
Current protocols in microbiology 33 (1), 15K. 2.1-15K. 2.61, 2014
1032014
Interleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells
JA Harker, A Godlee, JL Wahlsten, DCP Lee, LG Thorne, D Sawant, ...
Journal of virology 84 (8), 4073-4082, 2010
752010
Noroviruses co-opt the function of host proteins VAPA and VAPB for replication via a phenylalanine–phenylalanine-acidic-tract-motif mimic in nonstructural viral protein NS1/2
BT McCune, W Tang, J Lu, JB Eaglesham, L Thorne, AE Mayer, E Condiff, ...
MBio 8 (4), e00668-17, 2017
642017
High-resolution functional profiling of the norovirus genome
L Thorne, D Bailey, I Goodfellow
Journal of virology 86 (21), 11441-11456, 2012
552012
HIV-1 Vpr antagonizes cGAS sensing by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport
H Khan, RP Sumner, J Rasaiyaah, CP Tan, MT Rodriguez-Plata, ...
bioRxiv, 2020
48*2020
Are evolution and the intracellular innate immune system key determinants in HIV transmission?
RP Sumner, LG Thorne, DL Fink, H Khan, RS Milne, GJ Towers
Frontiers in immunology 8, 1246, 2017
422017
The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis
MA Yunus, X Lin, D Bailey, I Karakasiliotis, Y Chaudhry, S Vashist, ...
Journal of virology 89 (2), 1218-1229, 2015
412015
Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B. 1.1. 7 variant
AK Reuschl, LG Thorne, L Zuliani-Alvarez, M Bouhaddou, K Obernier, ...
bioRxiv, 2021
372021
Norovirus polymerase fidelity contributes to viral transmission in vivo
A Arias, L Thorne, E Ghurburrun, D Bailey, I Goodfellow
MSphere 1 (5), 2016
332016
Advances toward a norovirus antiviral: from classical inhibitors to lethal mutagenesis
L Thorne, A Arias, I Goodfellow
The Journal of infectious diseases 213 (suppl_1), S27-S31, 2016
332016
Reverse genetics mediated recovery of infectious murine norovirus
A Arias, L Ureña, L Thorne, MA Yunus, I Goodfellow
JoVE (Journal of Visualized Experiments), e4145, 2012
332012
Characterisation of B. 1.1. 7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.
SJ Dicken, MJ Murray, LG Thorne, AK Reuschl, C Forrest, ...
bioRxiv, 2021
322021
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