| The ribosome modulates nascent protein folding CM Kaiser, DH Goldman, JD Chodera, I Tinoco Jr, C Bustamante Science 334 (6063), 1723-1727, 2011 | 348 | 2011 |
| ClpX (P) generates mechanical force to unfold and translocate its protein substrates RA Maillard, G Chistol, M Sen, M Righini, J Tan, CM Kaiser, C Hodges, ... Cell 145 (3), 459-469, 2011 | 335 | 2011 |
| Real-time observation of trigger factor function on translating ribosomes CM Kaiser, HC Chang, VR Agashe, SK Lakshmipathy, SA Etchells, ... Nature 444 (7118), 455-460, 2006 | 278 | 2006 |
| Mechanical force releases nascent chain–mediated ribosome arrest in vitro and in vivo DH Goldman, CM Kaiser, A Milin, M Righini, I Tinoco Jr, C Bustamante Science 348 (6233), 457-460, 2015 | 264 | 2015 |
| Single-molecule studies of protein folding with optical tweezers C Bustamante, L Alexander, K Maciuba, CM Kaiser Annual review of biochemistry 89 (1), 443-470, 2020 | 178 | 2020 |
| De novo folding of GFP fusion proteins: high efficiency in eukaryotes but not in bacteria HC Chang, CM Kaiser, FU Hartl, JM Barral Journal of molecular biology 353 (2), 397-409, 2005 | 137 | 2005 |
| The ribosome cooperates with a chaperone to guide multi-domain protein folding K Liu, K Maciuba, CM Kaiser Molecular cell 74 (2), 310-319. e7, 2019 | 95 | 2019 |
| Identification of nascent chain interaction sites on trigger factor SK Lakshmipathy, S Tomic, CM Kaiser, HC Chang, P Genevaux, ... Journal of Biological Chemistry 282 (16), 12186-12193, 2007 | 90 | 2007 |
| The ribosome destabilizes native and non‐native structures in a nascent multidomain protein K Liu, JE Rehfus, E Mattson, CM Kaiser Protein Science 26 (7), 1439-1451, 2017 | 60 | 2017 |
| Mechanisms of cellular proteostasis: Insights from single molecule approaches C Bustamante, CM Kaiser, AR Maillard, D Goldman, C Wilson Annu Rev Biophys 43, 119-140, 2014 | 51 | 2014 |
| Folding up and moving on—nascent protein folding on the ribosome CM Kaiser, K Liu Journal of molecular biology 430 (22), 4580-4591, 2018 | 47 | 2018 |
| Energetic dependencies dictate folding mechanism in a complex protein K Liu, X Chen, CM Kaiser Proceedings of the National Academy of Sciences 116 (51), 25641-25648, 2019 | 40 | 2019 |
| The SecA motor generates mechanical force during protein translocation R Gupta, D Toptygin, CM Kaiser Nature Communications 11 (1), 3802, 2020 | 36 | 2020 |
| Next generation single-molecule techniques: Imaging, labeling, and manipulation in vitro and in cellulo T Ha, C Kaiser, S Myong, B Wu, J Xiao Molecular cell 82 (2), 304-314, 2022 | 35 | 2022 |
| Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter CM Kaiser, PJ Bujalowski, L Ma, J Anderson, HF Epstein, AF Oberhauser Biophysical journal 102 (9), 2212-2219, 2012 | 28 | 2012 |
| Bayesian hidden Markov model analysis of single-molecule force spectroscopy: Characterizing kinetics under measurement uncertainty JD Chodera, P Elms, F Noé, B Keller, CM Kaiser, A Ewall-Wice, ... arXiv preprint arXiv:1108.1430, 2011 | 28 | 2011 |
| Single-molecule chemo-mechanical spectroscopy provides structural identity of folding intermediates HN Motlagh, D Toptygin, CM Kaiser, VJ Hilser Biophysical journal 110 (6), 1280-1290, 2016 | 25 | 2016 |
| Synthesis runs counter to directional folding of a nascent protein domain X Chen, N Rajasekaran, K Liu, CM Kaiser Nature Communications 11 (1), 5096, 2020 | 20 | 2020 |
| Probing the Mechanisms of Translation with Force CM Kaiser, IJ Tinoco Chemical Reviews 114, 3266-3280, 2014 | 19 | 2014 |
| Facile tethering of stable and unstable proteins for optical tweezers experiments K Maciuba, F Zhang, CM Kaiser Biophysical Journal 120 (13), 2691-2700, 2021 | 16 | 2021 |
