Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells FA Suprynowicz, G Upadhyay, E Krawczyk, SC Kramer, JD Hebert, X Liu, ... Proceedings of the National Academy of Sciences 109 (49), 20035-20040, 2012 | 335 | 2012 |
Macrophage-secreted TNFα and TGFβ1 influence migration speed and persistence of cancer cells in 3D tissue culture via independent pathways R Li, JD Hebert, TA Lee, H Xing, A Boussommier-Calleja, RO Hynes, ... Cancer research 77 (2), 279-290, 2017 | 113 | 2017 |
Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches JD Hebert, SA Myers, A Naba, G Abbruzzese, JM Lamar, SA Carr, ... Cancer research 80 (7), 1475-1485, 2020 | 102 | 2020 |
The human papillomavirus type 16 E5 oncoprotein inhibits epidermal growth factor trafficking independently of endosome acidification FA Suprynowicz, E Krawczyk, JD Hebert, SR Sudarshan, V Simic, ... Journal of virology 84 (20), 10619-10629, 2010 | 94 | 2010 |
Dissecting metastasis using preclinical models and methods JD Hebert, JW Neal, MM Winslow Nature Reviews Cancer 23 (6), 391-407, 2023 | 41 | 2023 |
The human papillomavirus type 16 E5 oncoprotein translocates calpactin I to the perinuclear region E Krawczyk, FA Suprynowicz, JD Hebert, CM Kamonjoh, R Schlegel Journal of virology 85 (21), 10968-10975, 2011 | 35 | 2011 |
Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ... Nature cell biology 25 (1), 159-169, 2023 | 21 | 2023 |
The scaffold protein IQGAP1 is crucial for extravasation and metastasis JD Hebert, C Tian, JM Lamar, S Rickelt, G Abbruzzese, X Liu, RO Hynes Scientific Reports 10 (1), 2439, 2020 | 16 | 2020 |
Combinatorial inactivation of tumor suppressors efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities M Yousefi, G Boross, C Weiss, CW Murray, JD Hebert, H Cai, EL Ashkin, ... Cancer research 82 (8), 1589-1602, 2022 | 15 | 2022 |
Aging represses lung tumorigenesis and alters tumor suppression EG Shuldiner, S Karmakar, MK Tsai, JD Hebert, YJ Tang, L Andrejka, ... BioRxiv, 2024.05. 28.596319, 2024 | 4 | 2024 |
Modeling the genomic complexity of human cancer using Cas12a mice. JD Hebert, H Xu, YJ Tang, PA Ruiz, C Detrick, J Wang, NW Hughes, ... Biorxiv: the Preprint Server for Biology, 2024 | 3 | 2024 |
Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes YJ Tang, H Xu, NW Hughes, SH Kim, P Ruiz, EG Shuldiner, SS Lopez, ... bioRxiv, 2024.08. 19.607671, 2024 | 2 | 2024 |
Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis JD Hebert, YJ Tang, L Andrejka, SS Lopez, DA Petrov, G Boross, ... bioRxiv, 2024.03. 07.583981, 2024 | 2 | 2024 |
Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ... bioRxiv, 2021.07. 08.451571, 2021 | 2 | 2021 |
A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis EL Ashkin, YJ Tang, H Xu, KL Hung, JA Belk, H Cai, SS Lopez, ... Journal of Experimental Medicine 222 (1), e20240765, 2024 | 1 | 2024 |
Efficient and multiplexed somatic genome editing with Cas12a mice JD Hebert, H Xu, YJ Tang, PA Ruiz, CR Detrick, J Wang, NW Hughes, ... bioRxiv, 2024.03. 07.583774, 2024 | 1 | 2024 |
Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities M Yousefi, G Boross, C Weiss, CW Murray, JD Hebert, H Cai, EL Ashkin, ... bioRxiv, 2021.10. 20.464849, 2021 | 1 | 2021 |
Combinatorial in vivo genome editing identifies widespread epistasis and an accessible fitness landscape during lung tumorigenesis JD Hebert, YJ Tang, M Szamecz, L Andrejka, SS Lopez, DA Petrov, ... Molecular Biology and Evolution, msaf023, 2025 | | 2025 |
Dissecting the role of Stag2 in lung adenocarcinoma EL Ashkin, H Cai, YJ Tang, C Li, SK Chew, K Hung, J Belk, S Karmakar, ... Cancer Research 82 (12_Supplement), 821-821, 2022 | | 2022 |
A journey to deconvolute the multifaceted functions and context-dependency of cancer driver genes H Cai, SK Chew, C Li, CW Murray, L Andrejka, JD Hebert, MK Tsai, ... Cancer Research 82 (12_Supplement), 827-827, 2022 | | 2022 |