The nf-core framework for community-curated bioinformatics pipelines PA Ewels, A Peltzer, S Fillinger, H Patel, J Alneberg, A Wilm, MU Garcia, ... Nature biotechnology 38 (3), 276-278, 2020 | 2050 | 2020 |
Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection H Aegerter, J Kulikauskaite, S Crotta, H Patel, G Kelly, EM Hessel, ... Nature immunology 21 (2), 145-157, 2020 | 307 | 2020 |
Chromatin controls DNA replication origin selection, lagging-strand synthesis, and replication fork rates CF Kurat, JTP Yeeles, H Patel, A Early, JFX Diffley Molecular cell 65 (1), 117-130, 2017 | 266 | 2017 |
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair N Kanu, E Grönroos, P Martinez, RA Burrell, X Yi Goh, J Bartkova, ... Oncogene 34 (46), 5699-5708, 2015 | 201 | 2015 |
The linker histone H1. 0 generates epigenetic and functional intratumor heterogeneity CM Torres, A Biran, MJ Burney, H Patel, T Henser-Brownhill, AHS Cohen, ... Science 353 (6307), aaf1644, 2016 | 185 | 2016 |
The Scc2–Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions L Lopez-Serra, G Kelly, H Patel, A Stewart, F Uhlmann Nature genetics 46 (10), 1147-1151, 2014 | 155 | 2014 |
ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism R Desai, AE Frazier, R Durigon, H Patel, AW Jones, I Dalla Rosa, NJ Lake, ... Brain 140 (6), 1595-1610, 2017 | 144 | 2017 |
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD G Hewitt, V Borel, S Segura-Bayona, T Takaki, P Ruis, R Bellelli, ... Molecular cell 81 (4), 767-783. e11, 2021 | 122 | 2021 |
Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors K Fugger, I Bajrami, M Silva Dos Santos, SJ Young, S Kunzelmann, ... Science 372 (6538), 156-165, 2021 | 107 | 2021 |
A role for chromatin remodeling in cohesin loading onto chromosomes S Muñoz, M Minamino, CS Casas-Delucchi, H Patel, F Uhlmann Molecular Cell 74 (4), 664-673. e5, 2019 | 94 | 2019 |
A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines Y Chen, NM Davidson, YK Wan, H Patel, F Yao, HM Low, C Hendra, ... BioRxiv, 2021.04. 21.440736, 2021 | 79 | 2021 |
Challenges to be faced in the reconstruction of metabolic networks from public databases MG Poolman, BK Bonde, A Gevorgyan, HH Patel, DA Fell IEE Proceedings-Systems Biology 153 (5), 379-384, 2006 | 78 | 2006 |
Genome-wide co-localization of Polycomb orthologs and their effects on gene expression in human fibroblasts H Pemberton, E Anderton, H Patel, S Brookes, H Chandler, R Palermo, ... Genome biology 15, 1-16, 2014 | 68 | 2014 |
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study A Fendler, L Au, STC Shepherd, F Byrne, M Cerrone, LA Boos, ... Nature Cancer 2 (12), 1321-1337, 2021 | 65 | 2021 |
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation R Blassberg, H Patel, T Watson, M Gouti, V Metzis, MJ Delás, J Briscoe Nature Cell Biology 24 (5), 633-644, 2022 | 64 | 2022 |
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry F Van Maldegem, K Valand, M Cole, H Patel, M Angelova, S Rana, ... Nature Communications 12 (1), 5906, 2021 | 60 | 2021 |
Division of labor between PCNA loaders in DNA replication and sister chromatid cohesion establishment HW Liu, C Bouchoux, M Panarotto, Y Kakui, H Patel, F Uhlmann Molecular cell 78 (4), 725-738. e4, 2020 | 57 | 2020 |
Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling DM Coda, T Gaarenstroom, P East, H Patel, DSJ Miller, A Lobley, ... Elife 6, e22474, 2017 | 56 | 2017 |
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53 A Crockford, LP Zalmas, E Grönroos, SM Dewhurst, N McGranahan, ... Annals of Oncology 28 (1), 149-156, 2017 | 53 | 2017 |
Epstein–Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression S Ramasubramanyan, K Osborn, R Al-Mohammad, ... Nucleic acids research 43 (7), 3563-3577, 2015 | 52 | 2015 |