Deep learning applications for predicting pharmacological properties of drugs and drug repurposing using transcriptomic data A Aliper, S Plis, A Artemov, A Ulloa, P Mamoshina, A Zhavoronkov Molecular pharmaceutics 13 (7), 2524-2530, 2016 | 660 | 2016 |
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy R Ravi, KA Noonan, V Pham, R Bedi, A Zhavoronkov, IV Ozerov, ... Nature communications 9 (1), 741, 2018 | 314 | 2018 |
Variation in genomic landscape of clear cell renal cell carcinoma across Europe G Scelo, Y Riazalhosseini, L Greger, L Letourneau, M Gonzàlez-Porta, ... Nature communications 5 (1), 5135, 2014 | 207 | 2014 |
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate PT Newton, L Li, B Zhou, C Schweingruber, M Hovorakova, M Xie, X Sun, ... Nature 567 (7747), 234-238, 2019 | 200 | 2019 |
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development IV Ozerov, KV Lezhnina, E Izumchenko, AV Artemov, S Medintsev, ... Nature communications 7 (1), 13427, 2016 | 161 | 2016 |
Design of efficient computational workflows for in silico drug repurposing Q Vanhaelen, P Mamoshina, AM Aliper, A Artemov, K Lezhnina, I Ozerov, ... Drug Discovery Today 22 (2), 210-222, 2017 | 157 | 2017 |
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin P Kameneva, AV Artemov, ME Kastriti, L Faure, TK Olsen, J Otte, ... Nature genetics 53 (5), 694-706, 2021 | 150 | 2021 |
Genome-wide DNA methylation profiling reveals epigenetic adaptation of stickleback to marine and freshwater conditions AV Artemov, NS Mugue, SM Rastorguev, S Zhenilo, AM Mazur, ... Molecular biology and evolution 34 (9), 2203-2213, 2017 | 127 | 2017 |
Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization F Cortese, D Klokov, A Osipov, J Stefaniak, A Moskalev, J Schastnaya, ... Oncotarget 9 (18), 14692, 2018 | 104 | 2018 |
Towards natural mimetics of metformin and rapamycin A Aliper, L Jellen, F Cortese, A Artemov, D Karpinsky-Semper, ... Aging (albany NY) 9 (11), 2245, 2017 | 96 | 2017 |
Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish M Xie, D Kamenev, M Kaucka, ME Kastriti, B Zhou, AV Artemov, M Storer, ... Proceedings of the National Academy of Sciences 116 (30), 15068-15073, 2019 | 70 | 2019 |
In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state A Aliper, AV Belikov, A Garazha, L Jellen, A Artemov, M Suntsova, ... Aging (Albany NY) 8 (9), 2127, 2016 | 69 | 2016 |
Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response V Glaros, R Rauschmeier, AV Artemov, A Reinhardt, S Ols, ... Immunity 54 (9), 2005-2023. e10, 2021 | 68 | 2021 |
A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation A Artemov, A Aliper, M Korzinkin, K Lezhnina, L Jellen, N Zhukov, ... Oncotarget 6 (30), 29347, 2015 | 64 | 2015 |
CpG traffic lights are markers of regulatory regions in human genome AV Lioznova, AM Khamis, AV Artemov, E Besedina, V Ramensky, ... BMC genomics 20, 1-12, 2019 | 49 | 2019 |
Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells MD West, I Labat, H Sternberg, D Larocca, I Nasonkin, KB Chapman, ... Oncotarget 9 (8), 7796, 2017 | 48 | 2017 |
1H NMR-based metabolic profiling of urinary tract infection: combining multiple statistical models and clinical data E Nevedomskaya, T Pacchiarotta, A Artemov, A Meissner, ... Metabolomics 8, 1227-1235, 2012 | 39 | 2012 |
Integrated deep learned transcriptomic and structure-based predictor of clinical trials outcomes AV Artemov, E Putin, Q Vanhaelen, A Aliper, IV Ozerov, A Zhavoronkov BioRxiv, 095653, 2016 | 35 | 2016 |
A review of the biomedical innovations for healthy longevity A Moskalev, V Anisimov, A Aliper, A Artemov, K Asadullah, D Belsky, ... Aging (Albany NY) 9 (1), 7, 2017 | 34 | 2017 |
Non-invasive prenatal diagnostics of aneuploidy using next-generation DNA sequencing technologies, and clinical considerations YN Nepomnyashchaya, AV Artemov, SA Roumiantsev, AG Roumyantsev, ... Clinical Chemistry and Laboratory Medicine (CCLM) 51 (6), 1141-1154, 2013 | 33 | 2013 |