Mechanisms of OCT4-SOX2 motif readout on nucleosomes AK Michael, RS Grand, L Isbel, S Cavadini, Z Kozicka, G Kempf, ... Science 368 (6498), 1460-1465, 2020 | 215 | 2020 |
An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse L Daxinger, SK Harten, H Oey, T Epp, L Isbel, E Huang, N Whitelaw, ... Genome biology 14, 1-17, 2013 | 106 | 2013 |
Generating specificity in genome regulation through transcription factor sensitivity to chromatin L Isbel, RS Grand, D Schübeler Nature Reviews Genetics 23 (12), 728-740, 2022 | 96 | 2022 |
Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions H Oey, L Isbel, P Hickey, B Ebaid, E Whitelaw Epigenetics & chromatin 8, 1-12, 2015 | 76 | 2015 |
BANP opens chromatin and activates CpG-island-regulated genes RS Grand, L Burger, C Gräwe, AK Michael, L Isbel, D Hess, L Hoerner, ... Nature 596 (7870), 133-137, 2021 | 69 | 2021 |
CG dinucleotides enhance promoter activity independent of DNA methylation D Hartl, AR Krebs, RS Grand, T Baubec, L Isbel, C Wirbelauer, L Burger, ... Genome research 29 (4), 554-563, 2019 | 64 | 2019 |
Cooperation between bHLH transcription factors and histones for DNA access AK Michael, L Stoos, P Crosby, N Eggers, XY Nie, K Makasheva, ... Nature 619 (7969), 385-393, 2023 | 54 | 2023 |
Endogenous retroviruses in mammals: an emerging picture of how ERVs modify expression of adjacent genes L Isbel, E Whitelaw Bioessays 34 (9), 734-738, 2012 | 38 | 2012 |
Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype L Daxinger, H Oey, L Isbel, NC Whitelaw, NA Youngson, A Spurling, ... Scientific reports 6 (1), 25004, 2016 | 31 | 2016 |
Trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome L Isbel, R Srivastava, H Oey, A Spurling, L Daxinger, H Puthalakath, ... PLoS genetics 11 (12), e1005693, 2015 | 31 | 2015 |
Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse L Isbel, L Prokopuk, H Wu, L Daxinger, H Oey, A Spurling, AJ Lawther, ... Elife 5, e15082, 2016 | 29 | 2016 |
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53 L Isbel, M Iskar, S Durdu, J Weiss, RS Grand, E Hietter-Pfeiffer, Z Kozicka, ... Nature Structural & Molecular Biology 30 (7), 948-957, 2023 | 24 | 2023 |
The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers SK Harten, H Oey, LM Bourke, V Bharti, L Isbel, L Daxinger, P Faou, ... BMC biology 13, 1-15, 2015 | 23 | 2015 |
Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice AM Russo, AJ Lawther, BM Prior, L Isbel, WG Somers, JA Lesku, ... Behavioural Brain Research 359, 918-926, 2019 | 18 | 2019 |
ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers R Yelagandula, K Stecher, M Novatchkova, L Michetti, G Michlits, J Wang, ... Nature cell biology 25 (1), 42-55, 2023 | 13 | 2023 |
Commentary: Far-reaching hypothesis or a step too far: the inheritance of acquired characteristics L Isbel, E Whitelaw International journal of epidemiology 44 (4), 1109-1112, 2015 | 7 | 2015 |
Non-mendelian inheritance in mammals is highly constrained L Isbel, D Schübeler Cell 175 (5), 1179-1181, 2018 | 3 | 2018 |
Chromatin-dependent motif syntax defines differentiation trajectories S Durdu, M Iskar, L Isbel, L Hoerner, C Wirbelauer, L Burger, D Hess, ... bioRxiv, 2024.08. 05.606702, 2024 | 2 | 2024 |
Methodological question-begging about the causes of complex social traits JE Richters OSF, 2022 | 2 | 2022 |
ZFP462 targets heterochromatin to transposon-derived enhancers restricting transcription factor binding and expression of lineage-specifying genes R Yelagandula, K Stecher, M Novatchkova, L Michetti, G Michlits, J Wang, ... bioRxiv, 2021.06. 28.449463, 2021 | 1 | 2021 |