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Luke Isbel
Luke Isbel
South Australian immunoGENomics Cancer Institute
Підтверджена електронна адреса в adelaide.edu.au - Домашня сторінка
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Mechanisms of OCT4-SOX2 motif readout on nucleosomes
AK Michael, RS Grand, L Isbel, S Cavadini, Z Kozicka, G Kempf, ...
Science 368 (6498), 1460-1465, 2020
2152020
An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
L Daxinger, SK Harten, H Oey, T Epp, L Isbel, E Huang, N Whitelaw, ...
Genome biology 14, 1-17, 2013
1062013
Generating specificity in genome regulation through transcription factor sensitivity to chromatin
L Isbel, RS Grand, D Schübeler
Nature Reviews Genetics 23 (12), 728-740, 2022
962022
Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions
H Oey, L Isbel, P Hickey, B Ebaid, E Whitelaw
Epigenetics & chromatin 8, 1-12, 2015
762015
BANP opens chromatin and activates CpG-island-regulated genes
RS Grand, L Burger, C Gräwe, AK Michael, L Isbel, D Hess, L Hoerner, ...
Nature 596 (7870), 133-137, 2021
692021
CG dinucleotides enhance promoter activity independent of DNA methylation
D Hartl, AR Krebs, RS Grand, T Baubec, L Isbel, C Wirbelauer, L Burger, ...
Genome research 29 (4), 554-563, 2019
642019
Cooperation between bHLH transcription factors and histones for DNA access
AK Michael, L Stoos, P Crosby, N Eggers, XY Nie, K Makasheva, ...
Nature 619 (7969), 385-393, 2023
542023
Endogenous retroviruses in mammals: an emerging picture of how ERVs modify expression of adjacent genes
L Isbel, E Whitelaw
Bioessays 34 (9), 734-738, 2012
382012
Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype
L Daxinger, H Oey, L Isbel, NC Whitelaw, NA Youngson, A Spurling, ...
Scientific reports 6 (1), 25004, 2016
312016
Trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome
L Isbel, R Srivastava, H Oey, A Spurling, L Daxinger, H Puthalakath, ...
PLoS genetics 11 (12), e1005693, 2015
312015
Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse
L Isbel, L Prokopuk, H Wu, L Daxinger, H Oey, A Spurling, AJ Lawther, ...
Elife 5, e15082, 2016
292016
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
L Isbel, M Iskar, S Durdu, J Weiss, RS Grand, E Hietter-Pfeiffer, Z Kozicka, ...
Nature Structural & Molecular Biology 30 (7), 948-957, 2023
242023
The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers
SK Harten, H Oey, LM Bourke, V Bharti, L Isbel, L Daxinger, P Faou, ...
BMC biology 13, 1-15, 2015
232015
Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice
AM Russo, AJ Lawther, BM Prior, L Isbel, WG Somers, JA Lesku, ...
Behavioural Brain Research 359, 918-926, 2019
182019
ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
R Yelagandula, K Stecher, M Novatchkova, L Michetti, G Michlits, J Wang, ...
Nature cell biology 25 (1), 42-55, 2023
132023
Commentary: Far-reaching hypothesis or a step too far: the inheritance of acquired characteristics
L Isbel, E Whitelaw
International journal of epidemiology 44 (4), 1109-1112, 2015
72015
Non-mendelian inheritance in mammals is highly constrained
L Isbel, D Schübeler
Cell 175 (5), 1179-1181, 2018
32018
Chromatin-dependent motif syntax defines differentiation trajectories
S Durdu, M Iskar, L Isbel, L Hoerner, C Wirbelauer, L Burger, D Hess, ...
bioRxiv, 2024.08. 05.606702, 2024
22024
Methodological question-begging about the causes of complex social traits
JE Richters
OSF, 2022
22022
ZFP462 targets heterochromatin to transposon-derived enhancers restricting transcription factor binding and expression of lineage-specifying genes
R Yelagandula, K Stecher, M Novatchkova, L Michetti, G Michlits, J Wang, ...
bioRxiv, 2021.06. 28.449463, 2021
12021
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