The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets F Altamura, R Rajesh, CMC Catta‐Preta, NS Moretti, I Cestari Drug development research 83 (2), 225-252, 2022 | 89 | 2022 |
Genetically Validated Drug Targets in Leishmania: Current Knowledge and Future Prospects NG Jones, CMC Catta-Preta, APCA Lima, JC Mottram ACS infectious diseases 4 (4), 467-477, 2018 | 86 | 2018 |
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival N Baker, CMC Catta-Preta, R Neish, J Sadlova, B Powell, ... Nature communications 12 (1), 1244, 2021 | 84 | 2021 |
Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family MCM Motta, ACA Martins, SSA de Souza, CMC Catta-Preta, R Silva, ... PloS one 8 (4), e60209, 2013 | 68 | 2013 |
The Bacterium Endosymbiont of Crithidia deanei Undergoes Coordinated Division with the Host Cell Nucleus MCM Motta, CMC Catta-Preta, S Schenkman, ACA Martins, K Miranda, ... PLoS One 5 (8), e12415, 2010 | 55 | 2010 |
Leishmania flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host JD Sunter, R Yanase, Z Wang, CMC Catta-Preta, F Moreira-Leite, ... Proceedings of the National Academy of Sciences 116 (13), 6351-6360, 2019 | 53 | 2019 |
Essential roles for deubiquitination in Leishmania life cycle progression A Damianou, RJ Burge, CMC Catta-Preta, V Geoghegan, YR Nievas, ... PLoS pathogens 16 (6), e1008455, 2020 | 48 | 2020 |
Endosymbiosis in trypanosomatid protozoa: the bacterium division is controlled during the host cell cycle CMC Catta-Preta, FL Brum, CC da Silva, AA Zuma, MC Elias, W de Souza, ... Frontiers in microbiology 6, 520, 2015 | 43 | 2015 |
Hinge binder scaffold hopping identifies potent calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) inhibitor chemotypes BJ Eduful, SN O’Byrne, L Temme, CRM Asquith, Y Liang, A Picado, ... Journal of medicinal chemistry 64 (15), 10849-10877, 2021 | 25 | 2021 |
The symbiotic bacterium fuels the energy metabolism of the host trypanosomatid Strigomonas culicis AC Loyola-Machado, AC Azevedo-Martins, CMC Catta-Preta, ... Protist 168 (2), 253-269, 2017 | 22 | 2017 |
Structural Characterization of the Cell Division Cycle in Strigomonas culicis, an Endosymbiont-Bearing Trypanosomatid FL Brum, CMC Catta-Preta, W De Souza, S Schenkman, MC Elias, ... Microscopy and Microanalysis 20 (1), 228-237, 2014 | 21 | 2014 |
Chromosomal assembly of the nuclear genome of the endosymbiont-bearing trypanosomatid Angomonas deanei JW Davey, CMC Catta-Preta, S James, S Forrester, MCM Motta, ... G3 11 (1), jkaa018, 2021 | 20 | 2021 |
The presence of a symbiotic bacterium in Strigomonas culicis is related to differential ecto-phosphatase activity and influences the mosquito–protozoa interaction CMC Catta-Preta, MTC Nascimento, MCF Garcia, EM Saraiva, ... International Journal for Parasitology 43 (7), 571-577, 2013 | 18 | 2013 |
Drug candidate and target for leishmaniasis CMC Catta-Preta, JC Mottram Nature 560 (7717), 171-172, 2018 | 16 | 2018 |
Evaluation of clan CD C11 peptidase PNT1 and other Leishmania mexicana cysteine peptidases as potential drug targets JS Grewal, CMC Catta-Preta, E Brown, J Anand, JC Mottram Biochimie 166, 150-160, 2019 | 15 | 2019 |
Expanded repertoire of kinetoplast associated proteins and unique mitochondrial DNA arrangement of symbiont-bearing trypanosomatids SSA de Souza, CM Catta-Preta, JMP Alves, DP Cavalcanti, MMG Teixeira, ... PLoS One 12 (11), e0187516, 2017 | 15 | 2017 |
Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis C Halliday, R Yanase, CMC Catta-Preta, F Moreira-Leite, J Myskova, ... PLoS Pathogens 16 (10), e1008494, 2020 | 13 | 2020 |
Reduction of Tubulin Expression in Angomonas deanei by RNAi Modifies the Ultrastructure of the Trypanosomatid Protozoan and Impairs Division of Its … CMC Catta‐Preta, B dos Santos Pascoalino, W de Souza, JC Mottram, ... Journal of Eukaryotic Microbiology 63 (6), 794-803, 2016 | 9 | 2016 |
Genome sequence of Leishmania mexicana MNYC/BZ/62/M379 expressing Cas9 and T7 RNA polymerase T Beneke, U Dobramysl, CMC Catta-Preta, JC Mottram, E Gluenz, ... Wellcome open research 7, 294, 2023 | 7 | 2023 |
HOP1 and HAP2 are conserved components of the meiosis-related machinery required for successful mating in Leishmania CMC Catta-Preta, TR Ferreira, K Ghosh, A Paun, D Sacks Nature Communications 14 (1), 7159, 2023 | 6 | 2023 |