Підписатись
Mohammed A. Dahab
Mohammed A. Dahab
Associate Professor, Medicinal Chemistry Dep., Faculty of pharmacy, Al-Azhar University
Підтверджена електронна адреса в azhar.edu.eg - Домашня сторінка
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Посилання
Рік
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies
H Elkady, A Elwan, HA El-Mahdy, AS Doghish, A Ismail, MS Taghour, ...
Journal of enzyme inhibition and medicinal chemistry 37 (1), 403-416, 2022
1112022
New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis
NA Alsaif, MA Dahab, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ...
Bioorganic Chemistry 110, 104807, 2021
872021
New bis ([1, 2, 4] triazolo)[4, 3-a: 3′, 4′-c] quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer …
MM Alanazi, HA Mahdy, NA Alsaif, AJ Obaidullah, HM Alkahtani, ...
Bioorganic Chemistry 112, 104949, 2021
792021
Molecular docking and dynamics simulations reveal the potential of anti-HCV drugs to inhibit COVID-19 main protease
AA Al-Karmalawy, R Alnajjar, M Dahab, A Metwaly, I Eissa
Pharmaceutical Sciences 27 (Covid-19), S109-S121, 2021
642021
New quinoxaline-based VEGFR-2 inhibitors: Design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies
MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, HM Alkahtani, ...
RSC advances 11 (48), 30315-30328, 2021
582021
Design and discovery of new antiproliferative 1, 2, 4-triazin-3 (2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site
IH Eissa, MA Dahab, MK Ibrahim, NA Alsaif, AZ Alanazi, SI Eissa, ...
Bioorganic Chemistry 112, 104965, 2021
572021
New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies
EB Elkaeed, MS Taghour, HA Mahdy, WM Eldehna, NM El-Deeb, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2191-2205, 2022
512022
Discovery of new quinoxaline-based derivatives as anticancer agents and potent VEGFR-2 inhibitors: Design, synthesis, and in silico study
MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, WA Alanazi, ...
Journal of Molecular Structure 1253, 132220, 2022
452022
Modified benzoxazole-based VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, and anti-proliferative evaluation
A Elwan, AE Abdallah, HA Mahdy, MA Dahab, MS Taghour, EB Elkaeed, ...
Molecules 27 (15), 5047, 2022
432022
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation
MS Taghour, HA Mahdy, MH Gomaa, A Aglan, MG Eldeib, A Elwan, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2063-2077, 2022
342022
Identification of new [1, 2, 4] triazolo [4, 3-a] quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies
NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, WA Alanazi, ...
Bioorganic & Medicinal Chemistry 46, 116384, 2021
312021
Hordatines as a potential inhibitor of COVID-19 main protease and RNA polymerase: an in-silico approach
MA Dahab, MM Hegazy, HS Abbass
Natural products and bioprospecting 10, 453-462, 2020
212020
New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations
HA Mahdy, H Elkady, MS Taghour, A Elwan, MA Dahab, MA Elkady, ...
Future medicinal chemistry 15 (14), 1233-1250, 2023
152023
Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti …
IH Eissa, R El-Haggar, MA Dahab, MF Ahmed, HA Mahdy, RI Alsantali, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1587-1599, 2022
142022
Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations
MA Dahab, HA Mahdy, H Elkady, MS Taghour, A Elwan, MA Elkady, ...
Journal of Biomolecular Structure and Dynamics 42 (8), 4214-4233, 2024
132024
New thiazolidine-2, 4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies
H Elkady, AA Abuelkhir, M Rashed, MS Taghour, MA Dahab, HA Mahdy, ...
Computational Biology and Chemistry 107, 107958, 2023
112023
Synthesis, biological evaluation and computer-aided discovery of new thiazolidine-2, 4-dione derivatives as potential antitumor VEGFR-2 inhibitors
H Elkady, OA El-Dardir, A Elwan, MS Taghour, HA Mahdy, MA Dahab, ...
RSC advances 13 (40), 27801-27827, 2023
112023
Molecular docking and dynamics simulation revealed the potential inhibitory activity of ACEIs against SARS-CoV-2 targeting hACE2 receptor
I Eissa, A Al-Karmalawy, MA Dahab, AM Metwaly, SS Elhady, EB Elkaeed, ...
Front. Chem 9, 227, 2021
112021
Design, synthesis, docking, MD simulations, and anti-proliferative evaluation of thieno[2,3-d]pyrimidine derivatives as new EGFR inhibitors
EA Sobh, MA Dahab, EB Elkaeed, AA Alsfouk, IM Ibrahim, AM Metwaly, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2220579, 2023
102023
Thieme Chemistry Journals Awardees–Where Are They Now? A Cascade Synthesis of 1, 2, 4-Triazin-3 (2H)-ones Using Nitrogen-Substituted Isocyanates
MA Dahab, JS Derasp, AM Beauchemin
Synlett 28 (04), 456-460, 2017
92017
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