Molecular docking and structure-based drug design strategies LG Ferreira, RN Dos Santos, G Oliva, AD Andricopulo Molecules 20 (7), 13384-13421, 2015 | 2392 | 2015 |
Structure of pentameric human serum amyloid P component J Emsley, HE White, BP O'hara, G Oliva, N Srinivasan, IJ Tickle, ... Nature 367 (6461), 338-345, 1994 | 632 | 1994 |
Virtual screening and its integration with modern drug design technologies AD Andricopulo, RVC Guido, G Oliva Current medicinal chemistry 15 (1), 37-46, 2008 | 292 | 2008 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 217 | 2022 |
The reactivity of five-coordinate Ru (II)(1, 4-bis (diphenylphosphino) butane) complexes with the N-donor ligands: ammonia, pyridine, 4-substituted pyridines, 2, 2′-bipyridine … SL Queiroz, AA Batista, G Oliva, MTP Gambardella, RHA Santos, ... Inorganica Chimica Acta 267 (2), 209-221, 1998 | 166 | 1998 |
Planejamento de fármacos, biotecnologia e química medicinal: aplicações em doenças infecciosas RVC Guido, AD Andricopulo, G Oliva Estudos avançados 24, 81-98, 2010 | 162 | 2010 |
Structure of an Odorant-Binding Protein from the Mosquito Aedes aegypti Suggests a Binding Pocket Covered by a pH-Sensitive “Lid” NR Leite, R Krogh, W Xu, Y Ishida, J Iulek, WS Leal, G Oliva PLoS One 4 (11), e8006, 2009 | 157 | 2009 |
Quimioterapia da doença de Chagas: estado da arte e perspectivas no desenvolvimento de novos fármacos LC Dias, MA Dessoy, JJN Silva, OH Thiemann, G Oliva, AD Andricopulo Química Nova 32, 2444-2457, 2009 | 150 | 2009 |
Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia DO Guimarães, WS Borges, CY Kawano, PH Ribeiro, GH Goldman, ... FEMS Immunology & Medical Microbiology 52 (1), 134-144, 2008 | 146 | 2008 |
Trypanosoma cruzi glycosomal glyceraldehyde‐3‐phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design DHF Souza, RC Garratt, APU Araújo, BG Guimarães, WDP Jesus, ... FEBS letters 424 (3), 131-135, 1998 | 142 | 1998 |
Set-up and experimental parameters of the protein crystallography beamline at the Brazilian National Synchrotron Laboratory I Polikarpov, LA Perles, RT De Oliveira, G Oliva, EE Castellano, ... Synchrotron Radiation 5 (2), 72-76, 1998 | 130 | 1998 |
Isolation and structural characterization of a cytotoxic L-amino acid oxidase from Agkistrodon contortrix laticinctus snake venom: preliminary crystallographic data DHF Souza, LM Eugenio, JE Fletcher, MS Jiang, RC Garratt, G Oliva, ... Archives of biochemistry and biophysics 368 (2), 285-290, 1999 | 128 | 1999 |
Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase AS Godoy, GMA Lima, KIZ Oliveira, NU Torres, FV Maluf, RVC Guido, ... Nature communications 8 (1), 14764, 2017 | 125 | 2017 |
Pyrano chalcones and a flavone from Neoraputia magnifica and their Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase-inhibitory activities DM Tomazela, MT Pupo, EAP Passador, MFGF da Silva, PC Vieira, ... Phytochemistry 55 (6), 643-651, 2000 | 118 | 2000 |
Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in bothropstoxin I, a dimeric Lys49‐phospholipase A2 homologue MT da Silva Giotto, RC Garratt, G Oliva, YP Mascarenhas, JR Giglio, ... Proteins: Structure, Function, and Bioinformatics 30 (4), 442-454, 1998 | 117 | 1998 |
Structure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 Å resolution F Pavão, MS Castilho, MT Pupo, RLA Dias, AG Correa, JB Fernandes, ... FEBS letters 520 (1-3), 13-17, 2002 | 113 | 2002 |
Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity JJN Silva, PMM Guedes, A Zottis, TL Balliano, FO Nascimento Silva, ... British journal of pharmacology 160 (2), 260-269, 2010 | 112 | 2010 |
Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 Å resolution G Oliva, MRM Fontes, RC Garratt, MM Altamirano, ML Calcagno, ... Structure 3 (12), 1323-1332, 1995 | 105 | 1995 |
Synthesis, Biological Evaluation, and Structure–Activity Relationships of Potent Noncovalent and Nonpeptidic Cruzain Inhibitors as Anti-Trypanosoma cruzi Agents RS Ferreira, MA Dessoy, I Pauli, ML Souza, R Krogh, AIL Sales, G Oliva, ... Journal of medicinal chemistry 57 (6), 2380-2392, 2014 | 102 | 2014 |
Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors RF Freitas, IM Prokopczyk, A Zottis, G Oliva, AD Andricopulo, ... Bioorganic & medicinal chemistry 17 (6), 2476-2482, 2009 | 100 | 2009 |