An Inv (16)(p13. 3q24. 3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia TA Gruber, AL Gedman, J Zhang, CS Koss, S Marada, HQ Ta, SC Chen, ... Cancer cell 22 (5), 683-697, 2012 | 288 | 2012 |
G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling SK Ogden, DL Fei, NS Schilling, YF Ahmed, J Hwa, DJ Robbins Nature 456 (7224), 967-970, 2008 | 256 | 2008 |
Frequent requirement of hedgehog signaling in non-small cell lung carcinoma Z Yuan, JA Goetz, S Singh, SK Ogden, WJ Petty, CC Black, VA Memoli, ... Oncogene 26 (7), 1046-1055, 2007 | 218 | 2007 |
Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles MR Marzahn, S Marada, J Lee, A Nourse, S Kenrick, H Zhao, ... The EMBO journal 35 (12), 1254-1275, 2016 | 208 | 2016 |
Regulation of Hedgehog signaling: a complex story SK Ogden, M Ascano Jr, MA Stegman, DJ Robbins Biochemical pharmacology 67 (5), 805-814, 2004 | 152 | 2004 |
Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2 SK Ogden, M Ascano, MA Stegman, LM Suber, JE Hooper, DJ Robbins Current biology 13 (22), 1998-2003, 2003 | 141 | 2003 |
Hepatitis B viral transactivator HBx alleviates p53-mediated repression of α-fetoprotein gene expression SK Ogden, KC Lee, MC Barton Journal of Biological Chemistry 275 (36), 27806-27814, 2000 | 124 | 2000 |
Smoothened regulation: a tale of two signals AM Arensdorf, S Marada, SK Ogden Trends in pharmacological sciences 37 (1), 62-72, 2016 | 114 | 2016 |
A direct intersection between p53 and transforming growth factor β pathways targets chromatin modification and transcription repression of the α-fetoprotein gene DS Wilkinson, SK Ogden, SA Stratton, JL Piechan, TT Nguyen, ... Molecular and cellular biology, 2005 | 102 | 2005 |
Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling R Rana, CE Carroll, HJ Lee, J Bao, S Marada, CRR Grace, CD Guibao, ... Nature communications 4 (1), 2965, 2013 | 89 | 2013 |
Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway SF Farzan, M Ascano, SK Ogden, M Sanial, A Brigui, A Plessis, ... Current Biology 18 (16), 1215-1220, 2008 | 68 | 2008 |
p53 targets chromatin structure alteration to repress α-fetoprotein gene expression SK Ogden, KC Lee, K Wernke-Dollries, SA Stratton, B Aronow, MC Barton Journal of Biological Chemistry 276 (45), 42057-42062, 2001 | 63 | 2001 |
Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex ET Hall, ME Dillard, DP Stewart, Y Zhang, B Wagner, RM Levine, ... Elife 10, e61432, 2021 | 50 | 2021 |
Dispatching sonic hedgehog: molecular mechanisms controlling deployment ET Hall, ER Cleverdon, SK Ogden Trends in cell biology 29 (5), 385-395, 2019 | 48 | 2019 |
Functional divergence in the role of N-linked glycosylation in smoothened signaling S Marada, G Navarro, A Truong, DP Stewart, AM Arensdorf, ... PLoS genetics 11 (8), e1005473, 2015 | 47 | 2015 |
The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner MA Stegman, JA Goetz, M Ascano, SK Ogden, KE Nybakken, DJ Robbins Journal of Biological Chemistry 279 (8), 7064-7071, 2004 | 41 | 2004 |
The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation CE Carroll, S Marada, DP Stewart, JX Ouyang, SK Ogden Development 139 (3), 612-621, 2012 | 35 | 2012 |
Cleavage activates dispatched for Sonic Hedgehog ligand release DP Stewart, S Marada, WJ Bodeen, A Truong, SM Sakurada, T Pandit, ... Elife 7, e31678, 2018 | 34 | 2018 |
Sonic hedgehog activates phospholipase A2 to enhance smoothened ciliary translocation AM Arensdorf, ME Dillard, JM Menke, MW Frank, CO Rock, SK Ogden Cell reports 19 (10), 2074-2087, 2017 | 32 | 2017 |
A fixation method to preserve cultured cell cytonemes facilitates mechanistic interrogation of morphogen transport WJ Bodeen, S Marada, A Truong, SK Ogden Development 144 (19), 3612-3624, 2017 | 31 | 2017 |