| Intranasal vaccination with messenger RNA as a new approach in gene therapy: use against tuberculosis JCC Lorenzi, APF Trombone, CD Rocha, LP Almeida, RL Lousada, ... BMC biotechnology 10, 1-11, 2010 | 185 | 2010 |
| Immunotherapy with plasmid DNA encoding mycobacterial hsp65 in association with chemotherapy is a more rapid and efficient form of treatment for tuberculosis in mice CL Silva, VLD Bonato, AAM Coelho-Castelo, AO De Souza, SA Santos, ... Gene Therapy 12 (3), 281-287, 2005 | 134 | 2005 |
| Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes RS Rosada, LG Torre, FG Frantz, APF Trombone, CR Zárate-Bladés, ... BMC immunology 9, 1-13, 2008 | 128 | 2008 |
| Single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protects mice against a virulent strain of Mycobacterium tuberculosis KM Lima, SA Santos, VMF Lima, AAM Coelho-Castelo, JM Rodrigues, ... Gene therapy 10 (8), 678-685, 2003 | 119 | 2003 |
| Toxoplasma gondii micronemal protein MIC1 is a lactose-binding lectin EV Lourenço, SR Pereira, VM Faça, AAM Coelho-Castelo, JR Mineo, ... Glycobiology 11 (7), 541-547, 2001 | 93 | 2001 |
| Immune regulatory effect of pHSP65 DNA therapy in pulmonary tuberculosis: activation of CD8+ cells, interferon‐γ recovery and reduction of lung injury VLD Bonato, EDC Gonçalves, EG Soares, RRS Júnior, A Sartori, ... Immunology 113 (1), 130-138, 2004 | 78 | 2004 |
| Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery AAM Coelho-Castelo, AP Trombone, RS Rosada, RR Santos, ... Genetic Vaccines and Therapy 4, 1-10, 2006 | 73 | 2006 |
| The synergy between structural stability and DNA-binding controls the antibody production in EPC/DOTAP/DOPE liposomes and DOTAP/DOPE lipoplexes LG de la Torre, RS Rosada, APF Trombone, FG Frantz, ... Colloids and Surfaces B: Biointerfaces 73 (2), 175-184, 2009 | 50 | 2009 |
| Immunomodulation and protection induced by DNA-hsp65 vaccination in an animal model of arthritis RR Santos-Junior, A Sartori, MD Franco, OGR Filho, AAM Coelho-Castelo, ... Human Gene Therapy 16 (11), 1338-1345, 2005 | 47 | 2005 |
| Comparison of different delivery systems of vaccination for the induction of protection against tuberculosis in mice KM Lima, VLD Bonato, LH Faccioli, IT Brandao, SA dos Santos, ... Vaccine 19 (25-26), 3518-3525, 2001 | 45 | 2001 |
| Cytotoxic T cells and mycobacteria CL Silva, VLD Bonato, KM Lima, AAM Coelho-Castelo, LH Faccioli, ... FEMS microbiology letters 197 (1), 11-18, 2001 | 40 | 2001 |
| HSP65 DNA as therapeutic strategy to treat experimental paracoccidioidomycosis AM Ribeiro, AL Bocca, AC Amaral, ACCO Souza, LH Faccioli, ... Vaccine 28 (6), 1528-1534, 2010 | 38 | 2010 |
| Comprehensive gene expression profiling in lungs of mice infected with Mycobacterium tuberculosis following DNAhsp65 immunotherapy CR Zárate‐Bladés, VLD Bonato, ELV da Silveira, MO e Paula, CM Junta, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2009 | 38 | 2009 |
| Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression R Rodrigues dos Santos Jr, A Sartori, VL Deperon Bonato, ... Clinical & Experimental Immunology 149 (3), 570-578, 2007 | 38 | 2007 |
| Resposta imune a doenças infecciosas AAM Coelho-Castelo, APF Trombone, CD Rocha, JCC Lorenzi Medicina (Ribeirão Preto) 42 (2), 127-142, 2009 | 33 | 2009 |
| B-lymphocytes in bone marrow or lymph nodes can take up plasmid DNA after intramuscular delivery AAM Coelho-Castelo, RR Santos, VLD Bonato, MC Jamur, C Oliver, ... Human gene therapy 14 (13), 1279-1285, 2003 | 32 | 2003 |
| The immune response to toxocariasis does not modify susceptibility to Mycobacterium tuberculosis infection in BALB/c mice FG Frantz, RS Rosada, WM Turato, CM Peres, AAM Coelho-Castelo, ... The American journal of tropical medicine and hygiene 77 (4), 691-698, 2007 | 31 | 2007 |
| Protective efficacy of different strategies employing Mycobacterium leprae heat-shock protein 65 against tuberculosis PRM Souza, CR Zárate-Bladés, JI Hori, SG Ramos, DS Lima, T Schneider, ... Expert opinion on biological therapy 8 (9), 1255-1264, 2008 | 29 | 2008 |
| Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells APF Trombone, CL Silva, LP Almeida, RS Rosada, KM Lima, C Oliver, ... Genetic Vaccines and Therapy 5, 1-8, 2007 | 27 | 2007 |
| A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells LH Franco, PF Wowk, CL Silva, APF Trombone, AAM Coelho-Castelo, ... Genetic vaccines and therapy 6, 1-11, 2008 | 26 | 2008 |
