| Solvated interaction energy (SIE) for scoring protein− ligand binding affinities. 1. Exploring the parameter space M Naïm, S Bhat, KN Rankin, S Dennis, SF Chowdhury, I Siddiqi, P Drabik, ... Journal of chemical information and modeling 47 (1), 122-133, 2007 | 444 | 2007 |
| The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme HA Lindner, N Fotouhi-Ardakani, V Lytvyn, P Lachance, T Sulea, ... Journal of virology 79 (24), 15199-15208, 2005 | 431 | 2005 |
| Molecular dynamics—Solvated interaction energy studies of protein–protein interactions: The MP1–p14 scaffolding complex Q Cui, T Sulea, JD Schrag, C Munger, MN Hung, M Naïm, M Cygler, ... Journal of molecular biology 379 (4), 787-802, 2008 | 173 | 2008 |
| Human cathepsin X: A cysteine protease with unique carboxypeptidase activity DK Nägler, R Zhang, W Tam, T Sulea, EO Purisima, R Ménard Biochemistry 38 (39), 12648-12654, 1999 | 159 | 1999 |
| Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain-like protease? T Sulea, HA Lindner, EO Purisima, R Ménard Journal of virology 79 (7), 4550-4551, 2005 | 125 | 2005 |
| The structure of chondroitin B lyase complexed with glycosaminoglycan oligosaccharides unravels a calcium-dependent catalytic machinery G Michel, K Pojasek, Y Li, T Sulea, RJ Linhardt, R Raman, V Prabhakar, ... Journal of Biological Chemistry 279 (31), 32882-32896, 2004 | 117 | 2004 |
| Specificity Determinants of Human Cathepsin S Revealed by Crystal Structures of Complexes, TA Pauly, T Sulea, M Ammirati, J Sivaraman, DE Danley, MC Griffor, ... Biochemistry 42 (11), 3203-3213, 2003 | 102 | 2003 |
| Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides SF Chowdhury, J Sivaraman, J Wang, G Devanathan, P Lachance, H Qi, ... Journal of medicinal chemistry 45 (24), 5321-5329, 2002 | 97 | 2002 |
| Improvement of the thermostability and activity of a pectate lyase by single amino acid substitutions, using a strategy based on melting-temperature-guided sequence alignment Z Xiao, H Bergeron, S Grosse, M Beauchemin, ML Garron, D Shaya, ... Applied and environmental microbiology 74 (4), 1183-1189, 2008 | 88 | 2008 |
| Full-length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen DK Nägler, T Sulea, R Ménard Biochemical and biophysical research communications 257 (2), 313-318, 1999 | 87 | 1999 |
| High incidence of ubiquitin‐like domains in human ubiquitin‐specific proteases X Zhu, R Ménard, T Sulea Proteins: Structure, Function, and Bioinformatics 69 (1), 1-7, 2007 | 79 | 2007 |
| Characterization of a pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2 … H Iwaki, T Muraki, S Ishihara, Y Hasegawa, KN Rankin, T Sulea, J Boyd, ... Journal of bacteriology 189 (9), 3502-3514, 2007 | 71 | 2007 |
| Solvated interaction energy (SIE) for scoring protein–ligand binding affinities. 2. Benchmark in the CSAR-2010 scoring exercise T Sulea, Q Cui, EO Purisima Journal of chemical information and modeling 51 (9), 2066-2081, 2011 | 68 | 2011 |
| Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment T Sulea, N Rohani, J Baardsnes, CR Corbeil, C Deprez, ... MAbs 12 (1), 1682866, 2020 | 64 | 2020 |
| Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate D Shaya, W Zhao, ML Garron, Z Xiao, Q Cui, Z Zhang, T Sulea, ... Journal of Biological Chemistry 285 (26), 20051-20061, 2010 | 63 | 2010 |
| The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme D Kohls, T Sulea, EO Purisima, RE MacKenzie, A Vrielink Structure 8 (1), 35-46, 2000 | 59 | 2000 |
| Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics R Shi, SS Lamb, B Zakeri, A Proteau, Q Cui, T Sulea, A Matte, GD Wright, ... Chemistry & Biology 16 (4), 401-410, 2009 | 54 | 2009 |
| Modeling of the bacterial luciferase‐flavin mononucleotide complex combining flexible docking with structure‐activity data LYC Lin, T Sulea, R Szittner, V Vassilyev, EO Purisima, EA Meighen Protein Science 10 (8), 1563-1571, 2001 | 52 | 2001 |
| Cathepsins X and B can be differentiated through their respective mono-and dipeptidyl carboxypeptidase activities C Therrien, P Lachance, T Sulea, EO Purisima, H Qi, E Ziomek, ... Biochemistry 40 (9), 2702-2711, 2001 | 51 | 2001 |
| Small-molecule inhibitors of the pseudaminic acid biosynthetic pathway: targeting motility as a key bacterial virulence factor R Ménard, IC Schoenhofen, L Tao, A Aubry, P Bouchard, CW Reid, ... Antimicrobial agents and chemotherapy 58 (12), 7430-7440, 2014 | 48 | 2014 |
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