Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction JR Muppidi, J Tschopp, RM Siegel Immunity 21 (4), 461-465, 2004 | 421 | 2004 |
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma JR Muppidi, R Schmitz, JA Green, W Xiao, AB Larsen, SE Braun, J An, ... Nature 516 (7530), 254-258, 2014 | 329 | 2014 |
Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death JR Muppidi, RM Siegel Nature immunology 5 (2), 182-189, 2004 | 286 | 2004 |
Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS) AA Lobito, FC Kimberley, JR Muppidi, H Komarow, AJ Jackson, KM Hull, ... Blood 108 (4), 1320-1327, 2006 | 284 | 2006 |
SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor–induced apoptosis at the plasma membrane RM Siegel, JR Muppidi, M Sarker, A Lobito, M Jen, D Martin, SE Straus, ... The Journal of cell biology 167 (4), 735-744, 2004 | 197 | 2004 |
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone JR Muppidi, TI Arnon, Y Bronevetsky, N Veerapen, M Tanaka, GS Besra, ... Journal of Experimental Medicine 208 (10), 1941-1948, 2011 | 83 | 2011 |
S-Geranylgeranyl-l-glutathione is a ligand for human B cell-confinement receptor P2RY8 E Lu, FD Wolfreys, JR Muppidi, Y Xu, JG Cyster Nature 567 (7747), 244-248, 2019 | 74 | 2019 |
Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis JR Muppidi, AA Lobito, M Ramaswamy, JK Yang, L Wang, H Wu, ... Cell Death & Differentiation 13 (10), 1641-1650, 2006 | 70 | 2006 |
The G protein–coupled receptor P2RY8 and follicular dendritic cells promote germinal center confinement of B cells, whereas S1PR3 can contribute to their dissemination JR Muppidi, E Lu, JG Cyster Journal of Experimental Medicine 212 (13), 2213-2222, 2015 | 63 | 2015 |
The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation BC Trindade, S Ceglia, A Berthelette, F Raso, K Howley, JR Muppidi, ... Immunity 54 (10), 2273-2287. e6, 2021 | 54 | 2021 |
Cutting edge: Rac GTPases sensitize activated T cells to die via Fas M Ramaswamy, C Dumont, AC Cruz, JR Muppidi, TS Gomez, ... The Journal of Immunology 179 (10), 6384-6388, 2007 | 54 | 2007 |
Rewiring of B cell receptor signaling by Epstein–Barr virus LMP2A K Fish, F Comoglio, AL Shaffer III, Y Ji, KT Pan, S Scheich, A Oellerich, ... Proceedings of the National Academy of Sciences 117 (42), 26318-26327, 2020 | 53 | 2020 |
Clathrin light chains’ role in selective endocytosis influences antibody isotype switching S Wu, SR Majeed, TM Evans, MD Camus, NML Wong, Y Schollmeier, ... Proceedings of the National Academy of Sciences 113 (35), 9816-9821, 2016 | 39 | 2016 |
TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone AR Albright, J Kabat, M Li, F Raso, A Reboldi, JR Muppidi Journal of Experimental Medicine 216 (11), 2531-2545, 2019 | 30 | 2019 |
Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma R Razzaghi, S Agarwal, N Kotlov, O Plotnikova, K Nomie, DW Huang, ... Journal of Experimental Medicine 218 (3), e20201173, 2020 | 28 | 2020 |
Phase 1b/2 study of vipor (venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) in relapsed/refractory B-cell lymphoma: safety, efficacy and molecular analysis C Melani, R Lakhotia, S Pittaluga, MD Miljkovic, JD Phelan, JR Muppidi, ... Blood 136, 44-45, 2020 | 20 | 2020 |
Combination targeted therapy in relapsed diffuse large B-cell lymphoma C Melani, R Lakhotia, S Pittaluga, JD Phelan, DW Huang, G Wright, ... New England Journal of Medicine 390 (23), 2143-2155, 2024 | 18 | 2024 |
Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients AJ Radtke, E Postovalova, A Varlamova, A Bagaev, M Sorokina, ... Cancer Cell 42 (3), 444-463. e10, 2024 | 18 | 2024 |
Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma GM Pindzola, R Razzaghi, RN Tavory, HT Nguyen, VM Morris, M Li, ... Blood, The Journal of the American Society of Hematology 140 (10), 1119-1131, 2022 | 18 | 2022 |
Targeting N-linked glycosylation for the therapy of aggressive lymphomas S Scheich, J Chen, J Liu, F Schnütgen, JC Enssle, M Ceribelli, ... Cancer discovery 13 (8), 1862-1883, 2023 | 14 | 2023 |