Targeted genome editing in human repopulating haematopoietic stem cells P Genovese, G Schiroli, G Escobar, T Di Tomaso, C Firrito, A Calabria, ... Nature 510 (7504), 235-240, 2014 | 719 | 2014 |
An Antibody-Deficiency Syndrome Due to Mutations in the CD19 Gene MC Van Zelm, I Reisli, M Van Der Burg, D Castaño, CJM Van Noesel, ... New England Journal of Medicine 354 (18), 1901-1912, 2006 | 664 | 2006 |
Human memory B cells originate from three distinct germinal center-dependent and-independent maturation pathways MA Berkowska, GJA Driessen, V Bikos, C Grosserichter-Wagener, ... Blood, The Journal of the American Society of Hematology 118 (8), 2150-2158, 2011 | 478 | 2011 |
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency MC Van Zelm, J Smet, B Adams, F Mascart, L Schandené, F Janssen, ... The Journal of clinical investigation 120 (4), 1265-1274, 2010 | 450 | 2010 |
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion MC Van Zelm, T Szczepanski, M Van Der Burg, JJM Van Dongen The Journal of experimental medicine 204 (3), 645-655, 2007 | 400 | 2007 |
Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells M Rakhmanov, B Keller, S Gutenberger, C Foerster, M Hoenig, ... Proceedings of the National Academy of Sciences 106 (32), 13451-13456, 2009 | 396 | 2009 |
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency V Bigley, M Haniffa, S Doulatov, XN Wang, R Dickinson, N McGovern, ... Journal of Experimental Medicine 208 (2), 227-234, 2011 | 383 | 2011 |
Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency K Warnatz, L Bossaller, U Salzer, A Skrabl-Baumgartner, W Schwinger, ... Blood 107 (8), 3045-3052, 2006 | 368 | 2006 |
Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma D González, M Van Der Burg, R García-Sanz, JA Fenton, AW Langerak, ... Blood, The Journal of the American Society of Hematology 110 (9), 3112-3121, 2007 | 330 | 2007 |
A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining M Van Der Burg, H IJspeert, NS Verkaik, T Turul, WW Wiegant, ... The Journal of clinical investigation 119 (1), 91-98, 2009 | 308 | 2009 |
Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations AW Langerak, T Szczepański, M Van der Burg, ILM Wolvers-Tettero, ... Leukemia 11 (12), 2192-2199, 1997 | 273 | 1997 |
Role of truncating mutations in MME gene in fetomaternal alloimmunisation and antenatal glomerulopathies H Debiec, J Nauta, F Coulet, M Van Der Burg, V Guigonisy, T Schurmans, ... The Lancet 364 (9441), 1252-1259, 2004 | 272 | 2004 |
Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood E Blanco, M Pérez-Andrés, S Arriba-Méndez, T Contreras-Sanfeliciano, ... Journal of Allergy and Clinical Immunology 141 (6), 2208-2219. e16, 2018 | 262 | 2018 |
Non-homologous end-joining, a sticky affair DC Van Gent, M Van Der Burg Oncogene 26 (56), 7731-7740, 2007 | 227 | 2007 |
Educational paper: The expanding clinical and immunological spectrum of severe combined immunodeficiency M van der Burg, AR Gennery European journal of pediatrics 170, 561-571, 2011 | 214 | 2011 |
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression MC Van Zelm, M Van Der Burg, D De Ridder, BH Barendregt, ... The Journal of Immunology 175 (9), 5912-5922, 2005 | 214 | 2005 |
A new type of radiosensitive T–B–NK+ severe combined immunodeficiency caused by a LIG4 mutation M van der Burg, LR van Veelen, NS Verkaik, WW Wiegant, NG Hartwig, ... The Journal of clinical investigation 116 (1), 137-145, 2006 | 212 | 2006 |
Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B–ALL provides improved strategies for selection of stable PCR targets … T Szczepanski, MJ Willemse, B Brinkhof, ER van Wering, M van der Burg, ... Blood, The Journal of the American Society of Hematology 99 (7), 2315-2323, 2002 | 211 | 2002 |
Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2 JC De Greef, J Wang, J Balog, JT Den Dunnen, RR Frants, ... The American Journal of Human Genetics 88 (6), 796-804, 2011 | 206 | 2011 |
TREC based newborn screening for severe combined immunodeficiency disease: a systematic review J van der Spek, RHH Groenwold, M van der Burg, JM van Montfrans Journal of clinical immunology 35, 416-430, 2015 | 191 | 2015 |