Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3814 | 2013 |
Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages EM Palsson-McDermott, AM Curtis, G Goel, MAR Lauterbach, FJ Sheedy, ... Cell metabolism 21 (1), 65-80, 2015 | 1276 | 2015 |
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis RD Rudic, P McNamara, AM Curtis, RC Boston, S Panda, JB Hogenesch, ... PLoS biology 2 (11), e377, 2004 | 1241 | 2004 |
Circadian clock proteins and immunity AM Curtis, MM Bellet, P Sassone-Corsi, LAJ O’Neill Immunity 40 (2), 178-186, 2014 | 639 | 2014 |
Circadian variation of blood pressure and the vascular response to asynchronous stress AM Curtis, Y Cheng, S Kapoor, D Reilly, TS Price, GA FitzGerald Proceedings of the National Academy of Sciences 104 (9), 3450-3455, 2007 | 471 | 2007 |
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 JO Early, D Menon, CA Wyse, MP Cervantes-Silva, Z Zaslona, RG Carroll, ... Proceedings of the National Academy of Sciences 115 (36), E8460-E8468, 2018 | 329 | 2018 |
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1 AM Curtis, CT Fagundes, G Yang, EM Palsson-McDermott, P Wochal, ... Proceedings of the National Academy of Sciences 112 (23), 7231-7236, 2015 | 317 | 2015 |
Histone acetyltransferase-dependent chromatin remodeling and the vascular clock AM Curtis, S Seo, EJ Westgate, RD Rudic, EM Smyth, D Chakravarti, ... Journal of Biological Chemistry 279 (8), 7091-7097, 2004 | 249 | 2004 |
Bioinformatic analysis of circadian gene oscillation in mouse aorta RD Rudic, P McNamara, D Reilly, T Grosser, AM Curtis, TS Price, ... Circulation 112 (17), 2716-2724, 2005 | 182 | 2005 |
p38 mitogen-activated protein kinase targets the production of proinflammatory endothelial microparticles AM Curtis, PF Wilkinson, M Gui, TL Gales, E Hu, JM Edelberg Journal of Thrombosis and Haemostasis 7 (4), 701-709, 2009 | 180 | 2009 |
Endothelial microparticles: sophisticated vesicles modulating vascular function AM Curtis, J Edelberg, R Jonas, WT Rogers, JS Moore, W Syed, ... Vascular medicine 18 (4), 204-214, 2013 | 135 | 2013 |
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages JK Dowling, R Afzal, LJ Gearing, MP Cervantes-Silva, S Annett, GM Davis, ... Nature communications 12 (1), 1460, 2021 | 132 | 2021 |
Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease CE Sutton, CM Finlay, M Raverdeau, JO Early, J DeCourcey, Z Zaslona, ... Nature communications 8 (1), 1923, 2017 | 127 | 2017 |
Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank CA Wyse, CA Celis Morales, N Graham, Y Fan, J Ward, AM Curtis, ... Annals of medicine 49 (5), 411-420, 2017 | 125 | 2017 |
Association of NOD2 with Crohn's disease in a homogenous Irish population E Bairead, DL Harmon, AM Curtis, Y Kelly, C O'Leary, M Gardner, ... European journal of human genetics 11 (3), 237-244, 2003 | 103 | 2003 |
A Sperm-Associated WD Repeat Protein Orthologous to Chlamydomonas PF20 Associates with Spag6, the Mammalian Orthologue of Chlamydomonas PF16 Z Zhang, R Sapiro, D Kapfhamer, M Bucan, J Bray, V Chennathukuzhi, ... Molecular and Cellular Biology 22 (22), 7993-8004, 2002 | 96 | 2002 |
Post-transcriptional circadian regulation in macrophages organizes temporally distinct immunometabolic states EJ Collins, MP Cervantes-Silva, GA Timmons, JR O'Siorain, AM Curtis, ... Genome research 31 (2), 171-185, 2021 | 82 | 2021 |
Innate rhythms: clocks at the center of monocyte and macrophage function GA Timmons, JR O'Siorain, OD Kennedy, AM Curtis, JO Early Frontiers in immunology 11, 1743, 2020 | 71 | 2020 |
Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease RA Colas, PR Souza, ME Walker, M Burton, Z Zasłona, AM Curtis, ... Circulation research 122 (6), 855-863, 2018 | 69 | 2018 |
Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling DF Reilly, AM Curtis, Y Cheng, EJ Westgate, RD Rudic, G Paschos, ... Arteriosclerosis, thrombosis, and vascular biology 28 (1), 121-126, 2008 | 67 | 2008 |