Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ... Nature biotechnology 35 (12), 1179-1187, 2017 | 536 | 2017 |
Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ... Human gene therapy 26 (7), 432-442, 2015 | 417 | 2015 |
Interaction between AIF and CHCHD4 regulates respiratory chain biogenesis E Hangen, O Feraud, S Lachkar, H Mou, N Doti, GM Fimia, N Lam, C Zhu, ... Molecular cell 58 (6), 1001-1014, 2015 | 229 | 2015 |
Resveratrol differentially modulates inflammatory responses of microglia and astrocytes X Lu, L Ma, L Ruan, Y Kong, H Mou, Z Zhang, Z Wang, JM Wang, Y Le Journal of neuroinflammation 7, 1-14, 2010 | 222 | 2010 |
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion H Mou, JL Smith, L Peng, H Yin, J Moore, XO Zhang, CQ Song, A Sheel, ... Genome biology 18, 1-8, 2017 | 203 | 2017 |
Oncogenic activation of the RNA binding protein NELFE and MYC signaling in hepatocellular carcinoma H Dang, A Takai, M Forgues, Y Pomyen, H Mou, W Xue, D Ray, KCH Ha, ... Cancer cell 32 (1), 101-114. e8, 2017 | 143 | 2017 |
Precision cancer mouse models through genome editing with CRISPR-Cas9 H Mou, Z Kennedy, DG Anderson, H Yin, W Xue Genome medicine 7, 1-11, 2015 | 135 | 2015 |
Genome-wide CRISPR screen identifies regulators of mitogen-activated protein kinase as suppressors of liver tumors in mice CQ Song, Y Li, H Mou, J Moore, A Park, Y Pomyen, S Hough, Z Kennedy, ... Gastroenterology 152 (5), 1161-1173. e1, 2017 | 131 | 2017 |
Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis S Beyaz, C Chung, H Mou, KE Bauer-Rowe, ME Xifaras, I Ergin, ... Cell Stem Cell 28 (11), 1922-1935. e5, 2021 | 115 | 2021 |
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins J Lee, H Mou, R Ibraheim, SQ Liang, P Liu, W Xue, EJ Sontheimer Rna 25 (11), 1421-1431, 2019 | 101 | 2019 |
Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cell growth through the formyl peptide receptor 1 Y Yang, Y Liu, X Yao, Y Ping, T Jiang, Q Liu, S Xu, J Huang, H Mou, ... The American journal of pathology 179 (3), 1504-1512, 2011 | 100 | 2011 |
Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans DM Özata, T Yu, H Mou, I Gainetdinov, C Colpan, K Cecchini, Y Kaymaz, ... Nature ecology & evolution 4 (1), 156-168, 2020 | 98 | 2020 |
A versatile reporter system for CRISPR-mediated chromosomal rearrangements Y Li, AI Park, H Mou, C Colpan, A Bizhanova, E Akama-Garren, N Joshi, ... Genome biology 16, 1-11, 2015 | 78 | 2015 |
Depletion of TRRAP induces p53‐independent senescence in liver cancer by down‐regulating mitotic genes SY Kwan, A Sheel, CQ Song, XO Zhang, T Jiang, H Dang, Y Cao, ... Hepatology 71 (1), 275-290, 2020 | 63 | 2020 |
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice D Wang, J Li, CQ Song, K Tran, H Mou, PH Wu, PWL Tai, CA Mendonca, ... Nature biotechnology 36 (9), 839-842, 2018 | 50 | 2018 |
A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression Z Li, H Mou, T Wang, J Xue, B Deng, L Qian, Y Zhou, W Gong, JM Wang, ... Cancer letters 328 (2), 278-284, 2013 | 45 | 2013 |
Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis H Mou, J Moore, SK Malonia, Y Li, DM Ozata, S Hough, CQ Song, ... Proceedings of the National Academy of Sciences 114 (14), 3648-3653, 2017 | 41 | 2017 |
Biologically active peptides interacting with the G protein-coupled formylpeptide receptors Y Le, JM Wang, X Liu, Y Kong, X Hou, L Ruan, H Mou Protein and Peptide Letters 14 (9), 846-853, 2007 | 37 | 2007 |
A path to translation: How 3D patient tumor avatars enable next generation precision oncology S Bose, M Barroso, MG Chheda, H Clevers, E Elez, S Kaochar, SE Kopetz, ... Cancer cell 40 (12), 1448-1453, 2022 | 36 | 2022 |
Associations of amylin with inflammatory markers and metabolic syndrome in apparently healthy Chinese X Hou, L Sun, Z Li, H Mou, Z Yu, H Li, P Jiang, D Yu, H Wu, X Ye, X Lin, ... PloS one 6 (9), e24815, 2011 | 35 | 2011 |