Підписатись
Garrett M Frampton
Garrett M Frampton
Foundation Medicine Inc.
Підтверджена електронна адреса в foundationmedicine.com
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Посилання
Рік
Histone H3K27ac separates active from poised enhancers and predicts developmental state
MP Creyghton, AW Cheng, GG Welstead, T Kooistra, BW Carey, ...
Proceedings of the National Academy of Sciences 107 (50), 21931-21936, 2010
46712010
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm …
JE Rosenberg, J Hoffman-Censits, T Powles, MS Van Der Heijden, ...
The Lancet 387 (10031), 1909-1920, 2016
39092016
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ...
Genome medicine 9, 1-14, 2017
32212017
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
GM Frampton, A Fichtenholtz, GA Otto, K Wang, SR Downing, J He, ...
Nature biotechnology 31 (11), 1023-1031, 2013
23062013
Tumor mutational burden as an independent predictor of response to immunotherapy in diverse cancers
AM Goodman, S Kato, L Bazhenova, SP Patel, GM Frampton, V Miller, ...
Molecular cancer therapeutics 16 (11), 2598-2608, 2017
22242017
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
A Marson, SS Levine, MF Cole, GM Frampton, T Brambrink, S Johnstone, ...
cell 134 (3), 521-533, 2008
17882008
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ...
Cancer discovery 8 (7), 822-835, 2018
14012018
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
D Lipson, M Capelletti, R Yelensky, G Otto, A Parker, M Jarosz, JA Curran, ...
Nature medicine 18 (3), 382-384, 2012
10942012
Densely interconnected transcriptional circuits control cell states in human hematopoiesis
N Novershtern, A Subramanian, LN Lawton, RH Mak, WN Haining, ...
Cell 144 (2), 296-309, 2011
10942011
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
A Marson, K Kretschmer, GM Frampton, ES Jacobsen, JK Polansky, ...
Nature 445 (7130), 931-935, 2007
9752007
Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic …
F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou, P Tong, J Izzo, ...
Cancer discovery 5 (8), 860-877, 2015
8632015
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ...
Cancer discovery 5 (8), 850-859, 2015
8152015
Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor–positive breast cancer
R Jeselsohn, R Yelensky, G Buchwalter, G Frampton, F Meric-Bernstam, ...
Clinical cancer research 20 (7), 1757-1767, 2014
7222014
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
WA Whyte, S Bilodeau, DA Orlando, HA Hoke, GM Frampton, CT Foster, ...
Nature 482 (7384), 221-225, 2012
6662012
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells
MG Guenther, GM Frampton, F Soldner, D Hockemeyer, M Mitalipova, ...
Cell stem cell 7 (2), 249-257, 2010
5722010
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity
H Beltran, R Yelensky, GM Frampton, K Park, SR Downing, ...
European urology 63 (5), 920-926, 2013
5672013
Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ...
Nature 580 (7804), 517-523, 2020
5612020
PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers
M Yarchoan, LA Albacker, AC Hopkins, M Montesion, K Murugesan, ...
JCI insight 4 (6), e126908, 2019
4922019
Targeted next generation sequencing identifies markers of response to PD-1 blockade
DB Johnson, GM Frampton, MJ Rioth, E Yusko, Y Xu, X Guo, RC Ennis, ...
Cancer immunology research 4 (11), 959-967, 2016
4842016
Association of patient characteristics and tumor genomics with clinical outcomes among patients with non–small cell lung cancer using a clinicogenomic database
G Singal, PG Miller, V Agarwala, G Li, G Kaushik, D Backenroth, A Gossai, ...
Jama 321 (14), 1391-1399, 2019
4832019
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