Mechanism of tissue‐specific farnesoid X receptor in suppressing the expression of genes in bile‐acid synthesis in mice B Kong, L Wang, JYL Chiang, Y Zhang, CD Klaassen, GL Guo Hepatology 56 (3), 1034-1043, 2012 | 450 | 2012 |
Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis T Li, M Matozel, S Boehme, B Kong, LM Nilsson, G Guo, E Ellis, ... Hepatology 53 (3), 996-1006, 2011 | 261 | 2011 |
Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet B Kong, JP Luyendyk, O Tawfik, GL Guo The Journal of pharmacology and experimental therapeutics 328 (1), 116-122, 2009 | 243 | 2009 |
Genome‐wide tissue‐specific farnesoid X receptor binding in mouse liver and intestine AM Thomas, SN Hart, B Kong, J Fang, X Zhong, GL Guo Hepatology 51 (4), 1410-1419, 2010 | 217 | 2010 |
Orally administered berberine modulates hepatic lipid metabolism by altering microbial bile acid metabolism and the intestinal FXR signaling pathway R Sun, N Yang, B Kong, B Cao, D Feng, X Yu, C Ge, J Huang, J Shen, ... Molecular pharmacology 91 (2), 110-122, 2017 | 182 | 2017 |
Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet S Feng, Z Dai, AB Liu, J Huang, N Narsipur, G Guo, B Kong, K Reuhl, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 174 | 2018 |
Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal J Schmitt, B Kong, B Stieger, O Tschopp, SM Schultze, M Rau, A Weber, ... Liver International 35 (4), 1133-1144, 2015 | 144 | 2015 |
Fibroblast growth factor 15 deficiency impairs liver regeneration in mice BO Kong, J Huang, Y Zhu, G Li, J Williams, S Shen, LM Aleksunes, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (10 …, 2014 | 123 | 2014 |
E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr‐1/SHP/EID1 network Y Zhang, N Xu, J Xu, B Kong, B Copple, GL Guo, L Wang Hepatology 60 (3), 919-930, 2014 | 122 | 2014 |
Hepatocyte‐specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice P Borude, G Edwards, C Walesky, F Li, X Ma, B Kong, GL Guo, U Apte Hepatology 56 (6), 2344-2352, 2012 | 113 | 2012 |
Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis S Byun, DH Kim, D Ryerson, YC Kim, H Sun, BO Kong, P Yau, G Guo, ... Nature communications 9 (1), 2590, 2018 | 80 | 2018 |
Soluble expression of disulfide bond containing proteins FGF15 and FGF19 in the cytoplasm of Escherichia coli B Kong, GL Guo PloS one 9 (1), e85890, 2014 | 74 | 2014 |
Bile acid homeostasis in a cholesterol 7α‐hydroxylase and sterol 27‐hydroxylase double knockout mouse model D Rizzolo, K Buckley, B Kong, L Zhan, J Shen, M Stofan, A Brinker, ... Hepatology 70 (1), 389-402, 2019 | 73 | 2019 |
Direct and indirect effects of fibroblast growth factor (FGF) 15 and FGF19 on liver fibrosis development JD Schumacher, BO Kong, J Wu, D Rizzolo, LE Armstrong, MD Chow, ... Hepatology 71 (2), 670-685, 2020 | 72 | 2020 |
Suppression of Autophagic Flux by Bile Acids in Hepatocytes S Manley, HM Ni, B Kong, U Apte, G Guo, WX Ding Toxicological Sciences 137 (2), 478-490, 2013 | 71 | 2013 |
Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes L Zhan, HX Liu, Y Fang, B Kong, Y He, X Zhong, J Fang, YJY Wan, ... PloS one 9 (9), e105930, 2014 | 65 | 2014 |
Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity S Manley, HM Ni, JA Williams, B Kong, L DiTacchio, G Guo, WX Ding Redox biology 2, 991-1002, 2014 | 64 | 2014 |
FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury B Kong, M Zhang, M Huang, D Rizzolo, LE Armstrong, JD Schumacher, ... Digestive and Liver Disease 51 (4), 570-576, 2019 | 62 | 2019 |
Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A YC Kim, S Seok, Y Zhang, J Ma, B Kong, G Guo, B Kemper, JK Kemper Nature communications 11 (1), 5969, 2020 | 61 | 2020 |
Bile acid homeostasis in female mice deficient in Cyp7a1 and Cyp27a1 D Rizzolo, B Kong, RE Taylor, A Brinker, M Goedken, B Buckley, GL Guo Acta Pharmaceutica Sinica B 11 (12), 3847-3856, 2021 | 60 | 2021 |