| The mutational landscape of lethal castration-resistant prostate cancer CS Grasso, YM Wu, DR Robinson, X Cao, SM Dhanasekaran, AP Khan, ... Nature 487 (7406), 239-243, 2012 | 2829 | 2012 |
| Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations DS Shin, JM Zaretsky, H Escuin-Ordinas, A Garcia-Diaz, S Hu-Lieskovan, ... Cancer discovery 7 (2), 188-201, 2017 | 1253 | 2017 |
| Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression JR Prensner, MK Iyer, OA Balbin, SM Dhanasekaran, Q Cao, JC Brenner, ... Nature biotechnology 29 (8), 742-749, 2011 | 1166 | 2011 |
| Multiple sequence alignment using partial order graphs C Lee, C Grasso, MF Sharlow Bioinformatics 18 (3), 452-464, 2002 | 984 | 2002 |
| Genome-wide detection of alternative splicing in expressed sequences of human genes B Modrek, A Resch, C Grasso, C Lee Nucleic acids research 29 (13), 2850-2859, 2001 | 817 | 2001 |
| Multi-stage differentiation defines melanoma subtypes with differential vulnerability to drug-induced iron-dependent oxidative stress J Tsoi, L Robert, K Paraiso, C Galvan, KM Sheu, J Lay, DJL Wong, M Atefi, ... Cancer cell 33 (5), 890-904. e5, 2018 | 800 | 2018 |
| Functionally defined therapeutic targets in diffuse intrinsic pontine glioma CS Grasso, Y Tang, N Truffaux, NE Berlow, L Liu, MA Debily, MJ Quist, ... Nature medicine 21 (6), 555-559, 2015 | 681 | 2015 |
| Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma KR Taylor, A Mackay, N Truffaux, YS Butterfield, O Morozova, C Philippe, ... Nature genetics 46 (5), 457-461, 2014 | 529 | 2014 |
| Genetic mechanisms of immune evasion in colorectal cancer CS Grasso, M Giannakis, DK Wells, T Hamada, XJ Mu, M Quist, JA Nowak, ... Cancer discovery 8 (6), 730-749, 2018 | 469 | 2018 |
| Chimeric transcript discovery by paired-end transcriptome sequencing CA Maher, N Palanisamy, JC Brenner, X Cao, S Kalyana-Sundaram, ... Proceedings of the National Academy of Sciences 106 (30), 12353-12358, 2009 | 427 | 2009 |
| Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer DR Robinson, S Kalyana-Sundaram, YM Wu, S Shankar, X Cao, B Ateeq, ... Nature medicine 17 (12), 1646-1651, 2011 | 403 | 2011 |
| Differential protein expression profiling by iTRAQ− 2DLC− MS/MS of lung Cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype VG Keshamouni, G Michailidis, CS Grasso, S Anthwal, JR Strahler, ... Journal of proteome research 5 (5), 1143-1154, 2006 | 344 | 2006 |
| Conserved interferon-γ signaling drives clinical response to immune checkpoint blockade therapy in melanoma CS Grasso, J Tsoi, M Onyshchenko, G Abril-Rodriguez, ... Cancer cell 38 (4), 500-515. e3, 2020 | 335 | 2020 |
| Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma A Ribas, D Lawrence, V Atkinson, S Agarwal, WH Miller Jr, MS Carlino, ... Nature medicine 25 (6), 936-940, 2019 | 332 | 2019 |
| Primary resistance to PD-1 blockade mediated by JAK1/2 mutations. Cancer Discov. 2017; 7: 188–201. doi: 10.1158/2159-8290 DS Shin, JM Zaretsky, H Escuin-Ordinas, A Garcia-Diaz, S Hu-Lieskovan, ... CD-16-1223, 0 | 237 | |
| Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors DH Hovelson, AS McDaniel, AK Cani, B Johnson, K Rhodes, PD Williams, ... Neoplasia 17 (4), 385-399, 2015 | 234 | 2015 |
| Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer JH Kim, SM Dhanasekaran, JR Prensner, X Cao, D Robinson, ... Genome research 21 (7), 1028-1041, 2011 | 223 | 2011 |
| FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer X Fu, R Jeselsohn, R Pereira, EF Hollingsworth, CJ Creighton, F Li, ... Proceedings of the National Academy of Sciences 113 (43), E6600-E6609, 2016 | 170 | 2016 |
| Combining partial order alignment and progressive multiple sequence alignment increases alignment speed and scalability to very large alignment problems C Grasso, C Lee Bioinformatics 20 (10), 1546-1556, 2004 | 169 | 2004 |
| Next-Gen Sequencing Exposes Frequent MED12 Mutations and Actionable Therapeutic Targets in Phyllodes Tumors AK Cani, DH Hovelson, AS McDaniel, S Sadis, MJ Haller, V Yadati, ... Molecular Cancer Research 13 (4), 613-619, 2015 | 147 | 2015 |
