Theo dõi
Paul A. Wadsworth
Paul A. Wadsworth
Resident Pathologist, Stanford University
Email được xác minh tại stanford.edu
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Intracellular fibroblast growth factor 14: emerging risk factor for brain disorders
J Di Re, PA Wadsworth, F Laezza
Frontiers in Cellular Neuroscience 11, 103, 2017
752017
Systematic identification of single amino acid variants in glioma stem-cell-derived chromosome 19 proteins
CF Lichti, E Mostovenko, PA Wadsworth, GC Lynch, BM Pettitt, ...
Journal of proteome research 14 (2), 778-786, 2015
262015
JAK2 regulates Nav1. 6 channel function via FGF14Y158 phosphorylation
PA Wadsworth, AK Singh, N Nguyen, NM Dvorak, CM Tapia, WK Russell, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (10), 118786, 2020
192020
High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na+ channel …
PA Wadsworth, O Folorunso, N Nguyen, AK Singh, D D’Amico, RT Powell, ...
Scientific reports 9 (1), 16890, 2019
182019
Sex-specific proteomic changes induced by genetic deletion of fibroblast growth factor 14 (FGF14), a regulator of neuronal ion channels
ML Sowers, J Di Re, PA Wadsworth, AS Shavkunov, C Lichti, K Zhang, ...
Proteomes 7 (1), 5, 2019
152019
Mapping of the FGF14: Nav1. 6 complex interface reveals FLPK as a functionally active peptide modulating excitability
AK Singh, PA Wadsworth, CM Tapia, G Aceto, SR Ali, H Chen, ...
Physiological reports 8 (14), e14505, 2020
112020
Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1. 6) protein-protein …
Z Liu, P Wadsworth, AK Singh, H Chen, P Wang, O Folorunso, P Scaduto, ...
Bioorganic & medicinal chemistry letters 29 (3), 413-419, 2019
112019
Bidirectional modulation of the voltage-gated sodium (Nav1. 6) channel by rationally designed peptidomimetics
NM Dvorak, PA Wadsworth, P Wang, H Chen, J Zhou, F Laezza
Molecules 25 (15), 3365, 2020
102020
Design, synthesis, and pharmacological evaluation of analogues derived from the PLEV tetrapeptide as protein–protein interaction modulators of voltage-gated sodium channel 1.6
P Wang, PA Wadsworth, NM Dvorak, AK Singh, H Chen, Z Liu, R Zhou, ...
Journal of medicinal chemistry 63 (20), 11522-11547, 2020
92020
Development of allosteric modulators of voltage-gated Na+ channels: A novel approach for an old target
NM Dvorak, PA Wadsworth, P Wang, J Zhou, F Laezza
Current topics in medicinal chemistry 21 (10), 841-848, 2021
72021
TNFR1 signaling converging on FGF14 controls neuronal hyperactivity and sickness behavior in experimental cerebral malaria
NM Dvorak, ND Domingo, CM Tapia, PA Wadsworth, M Marosi, ...
Journal of neuroinflammation 20 (1), 306, 2023
62023
Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na+ Channel 1.6 Enables Isoform-Selective Modulation
NM Dvorak, CM Tapia, AK Singh, TJ Baumgartner, P Wang, H Chen, ...
International journal of molecular sciences 22 (24), 13541, 2021
52021
Mobility but not balance limitations are associated with cognitive decline among older Hispanics
PA Wadsworth, NW Chen, M Raji, KS Markides, B Downer
Gerontology and geriatric medicine 6, 2333721420947952, 2020
42020
Bioluminescence Methodology for Ion Channel Studies
PA Wadsworth, AK Singh, N Nguyen, C Stephan, F Laezza
Patch Clamp Electrophysiology: Methods and Protocols, 191-228, 2021
22021
Enhanced motivated behavior mediated by pharmacological targeting of the FGF14/Nav1.6 complex in nucleus accumbens neurons
NM Dvorak, PA Wadsworth, G Aquino-Miranda, P Wang, DS Engelke, ...
Nature Communications 16 (1), 110, 2025
2025
Intraoperative Kinetics of Pro-Inflammatory Markers and Delayed-Graft Function During Kidney Transplantation.
PA Wadsworth, HL Stevenson, ML Kueht
AMERICAN JOURNAL OF TRANSPLANTATION 22, 514-514, 2022
2022
Functional evidence of a novel mechanism of allosteric modulation of the voltage gated sodium channel
NM Dvorak, P Wadsworth, AK Singh, C Tapia, P Wang, H Chen, J Zhou, ...
Biophysical Journal 121 (3), 503a, 2022
2022
Elucidating the Structural Constituents of Fibroblast Growth Factor 14 that Confer its Modulatory Effects on the Voltage-Gated Sodium Channel 1.6
NM Dvorak, P Wadsworth, P Wang, H Chen, J Zhou, F Laezza
Biophysical Journal 120 (3), 156a, 2021
2021
Developing Pharmacological Probes for Interrogation of the Circuitry of the Nucleus Accumbens
PA Wadsworth, A Singh, NM Dvorak, N Nguyen, G Aceto, E Troendle, ...
NEUROPSYCHOPHARMACOLOGY 45 (SUPPL 1), 93-93, 2020
2020
Regulation of signaling and function of the voltage-gated sodium channel complex by protein: protein interactions
PA Wadsworth
2020
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Bài viết 1–20