| Immunology of age-related macular degeneration J Ambati, JP Atkinson, BD Gelfand Nature Reviews Immunology 13 (6), 438-451, 2013 | 718 | 2013 |
| DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration H Kaneko, S Dridi, V Tarallo, BD Gelfand, BJ Fowler, WG Cho, ... Nature 471 (7338), 325-330, 2011 | 715 | 2011 |
| DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88 V Tarallo, Y Hirano, BD Gelfand, S Dridi, N Kerur, Y Kim, WG Cho, ... Cell, 2012 | 675 | 2012 |
| cGAS drives noncanonical-inflammasome activation in age-related macular degeneration N Kerur, S Fukuda, D Banerjee, Y Kim, D Fu, I Apicella, A Varshney, ... Nature medicine 24 (1), 50-61, 2018 | 252 | 2018 |
| Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity BJ Fowler, BD Gelfand, Y Kim, N Kerur, V Tarallo, Y Hirano, S Amarnath, ... Science 346 (6212), 1000-1003, 2014 | 244 | 2014 |
| TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy N Kerur, Y Hirano, V Tarallo, BJ Fowler, A Bastos-Carvalho, T Yasuma, ... Investigative ophthalmology & visual science 54 (12), 7395-7401, 2013 | 189 | 2013 |
| Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice BL Harry, JM Sanders, RE Feaver, M Lansey, TL Deem, A Zarbock, ... Arteriosclerosis, thrombosis, and vascular biology 28 (11), 2003-2008, 2008 | 174 | 2008 |
| Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation RE Feaver, BD Gelfand, C Wang, MA Schwartz, BR Blackman Circulation research 106 (11), 1703-1711, 2010 | 148 | 2010 |
| ERK1/2 activation is a therapeutic target in age-related macular degeneration S Dridi, Y Hirano, V Tarallo, Y Kim, BJ Fowler, BK Ambati, S Bogdanovich, ... Proceedings of the National Academy of Sciences 109 (34), 13781-13786, 2012 | 119 | 2012 |
| Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3 ME Kleinman, H Kaneko, WG Cho, S Dridi, BJ Fowler, AD Blandford, ... Molecular therapy 20 (1), 101-108, 2012 | 115 | 2012 |
| Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells RE Feaver, BD Gelfand, BR Blackman Nature communications 4 (1), 1525, 2013 | 113 | 2013 |
| DICER1/Alu RNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration Y Kim, V Tarallo, N Kerur, T Yasuma, BD Gelfand, A Bastos-Carvalho, ... Proceedings of the National Academy of Sciences 111 (45), 16082-16087, 2014 | 106 | 2014 |
| Iron toxicity in the retina requires Alu RNA and the NLRP3 inflammasome BD Gelfand, CB Wright, Y Kim, T Yasuma, R Yasuma, S Li, BJ Fowler, ... Cell reports 11 (11), 1686-1693, 2015 | 101 | 2015 |
| Hemodynamic activation of β-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression BD Gelfand, J Meller, AW Pryor, M Kahn, PDS Bortz, BR Wamhoff, ... Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1625-1633, 2011 | 80 | 2011 |
| Spatial and spectral heterogeneity of time‐varying shear stress profiles in the carotid bifurcation by phase‐contrast MRI BD Gelfand, FH Epstein, BR Blackman Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2006 | 68 | 2006 |
| Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration M Ambati, I Apicella, S Wang, S Narendran, H Leung, F Pereira, ... Proceedings of the National Academy of Sciences 118 (41), e2102975118, 2021 | 64 | 2021 |
| A revised hemodynamic theory of age-related macular degeneration BD Gelfand, J Ambati Trends in molecular medicine 22 (8), 656-670, 2016 | 63 | 2016 |
| Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration S Fukuda, A Varshney, BJ Fowler, S Wang, S Narendran, K Ambati, ... Proceedings of the National Academy of Sciences 118 (6), e2022751118, 2021 | 53 | 2021 |
| A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling D Banerjee, K Langberg, S Abbas, E Odermatt, P Yerramothu, M Volaric, ... Nature Communications 12 (1), 6207, 2021 | 51 | 2021 |
| Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development J Ambati, J Magagnoli, H Leung, S Wang, CA Andrews, D Fu, A Pandey, ... Nature communications 11 (1), 4737, 2020 | 50 | 2020 |
Benjamin FowlerMD, PhD, Maine Eye Center, Portland, MEEmail được xác minh tại maineeyecenter.com