Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ... Cell 178 (6), 1313-1328. e13, 2019 | 538 | 2019 |
Interleukin-10 directly inhibits CD8+ T cell function by enhancing N-glycan branching to decrease antigen sensitivity LK Smith, GM Boukhaled, SA Condotta, S Mazouz, JJ Guthmiller, R Vijay, ... Immunity 48 (2), 299-312. e5, 2018 | 270 | 2018 |
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets HL Dugan, CT Stamper, L Li, S Changrob, NW Asby, PJ Halfmann, ... Immunity, 2021 | 154* | 2021 |
Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial DI Bernstein, J Guptill, A Naficy, R Nachbagauer, F Berlanda-Scorza, ... The Lancet Infectious Diseases 20 (1), 80-91, 2020 | 143 | 2020 |
Broadly neutralizing antibodies target a haemagglutinin anchor epitope JJ Guthmiller, J Han, HA Utset, L Li, LYL Lan, C Henry, CT Stamper, ... Nature 602 (7896), 314-320, 2022 | 122 | 2022 |
PD-1 co-inhibitory and OX40 co-stimulatory crosstalk regulates helper T cell differentiation and anti-Plasmodium humoral immunity RA Zander, N Obeng-Adjei, JJ Guthmiller, DI Kulu, J Li, A Ongoiba, ... Cell host & microbe 17 (5), 628-641, 2015 | 118 | 2015 |
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans HL Dugan, JJ Guthmiller, P Arevalo, M Huang, YQ Chen, KE Neu, ... Science translational medicine 12 (573), eabd3601, 2020 | 109 | 2020 |
SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike JJ Guthmiller, O Stovicek, J Wang, S Changrob, L Li, P Halfmann, ... Mbio 12 (1), 2021 | 108 | 2021 |
Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria R Vijay, JJ Guthmiller, AJ Sturtz, FA Surette, KJ Rogers, RR Sompallae, ... Nature immunology 21 (7), 790-801, 2020 | 103 | 2020 |
Cutting edge: IL-10 is essential for the generation of germinal center B cell responses and anti-plasmodium humoral immunity JJ Guthmiller, AC Graham, RA Zander, RL Pope, NS Butler The Journal of Immunology 198 (2), 617-622, 2017 | 97 | 2017 |
Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria J Rivera-Correa, JJ Guthmiller, R Vijay, C Fernandez-Arias, ... Nature communications 8 (1), 1282, 2017 | 92 | 2017 |
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses JJ Guthmiller, LYL Lan, ML Fernández-Quintero, J Han, HA Utset, DJ Bitar, ... Immunity 53 (6), 1230-1244. e5, 2020 | 86 | 2020 |
Type I interferons induce T regulatory 1 responses and restrict humoral immunity during experimental malaria RA Zander, JJ Guthmiller, AC Graham, RL Pope, BE Burke, DJJ Carr, ... PLoS pathogens 12 (10), e1005945, 2016 | 78 | 2016 |
Harnessing immune history to combat influenza viruses JJ Guthmiller, PC Wilson Current opinion in immunology 53, 187-195, 2018 | 70 | 2018 |
Th1-like plasmodium-specific memory CD4+ T cells support humoral immunity RA Zander, R Vijay, AD Pack, JJ Guthmiller, AC Graham, SE Lindner, ... Cell reports 21 (7), 1839-1852, 2017 | 62 | 2017 |
Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID‐19 convalescent plasma clinical trial MLL Madariaga, JJ Guthmiller, S Schrantz, MO Jansen, C Christensen, ... Journal of internal medicine 289 (4), 559-573, 2021 | 60 | 2021 |
First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes JJ Guthmiller, J Han, L Li, AW Freyn, STH Liu, O Stovicek, CT Stamper, ... Science Translational Medicine 13 (596), eabg4535, 2021 | 58 | 2021 |
B Cell Responses against Influenza Viruses: Short-Lived Humoral Immunity against a Life-Long Threat JJ Guthmiller, HA Utset, PC Wilson Viruses 13 (6), 965, 2021 | 54 | 2021 |
An efficient method to generate monoclonal antibodies from human B cells JJ Guthmiller, HL Dugan, KE Neu, LYL Lan, PC Wilson Human Monoclonal Antibodies: Methods and Protocols, 109-145, 2019 | 54 | 2019 |
Biochemical patterns of antibody polyreactivity revealed through a bioinformatics-based analysis of CDR loops CT Boughter, MT Borowska, JJ Guthmiller, A Bendelac, PC Wilson, ... Elife 9, e61393, 2020 | 47 | 2020 |